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Items: 1 to 20 of 95

1.

Promoter hypermethylation in cancer silences LDHB, eliminating lactate dehydrogenase isoenzymes 1-4.

Maekawa M, Taniguchi T, Ishikawa J, Sugimura H, Sugano K, Kanno T.

Clin Chem. 2003 Sep;49(9):1518-20. No abstract available.

2.

Electrophoretic variant of a lactate dehydrogenase isoenzyme and selective promoter methylation of the LDHA gene in a human retinoblastoma cell line.

Maekawa M, Inomata M, Sasaki MS, Kaneko A, Ushiama M, Sugano K, Takayama J, Kanno T.

Clin Chem. 2002 Nov;48(11):1938-45.

3.

Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer.

Leiblich A, Cross SS, Catto JW, Phillips JT, Leung HY, Hamdy FC, Rehman I.

Oncogene. 2006 May 11;25(20):2953-60.

PMID:
16547507
4.

Transcriptional silencing of hedgehog-interacting protein by CpG hypermethylation and chromatic structure in human gastrointestinal cancer.

Taniguchi H, Yamamoto H, Akutsu N, Nosho K, Adachi Y, Imai K, Shinomura Y.

J Pathol. 2007 Oct;213(2):131-9.

PMID:
17724792
5.

Homo sapiens lactate dehydrogenase c (Ldhc) gene expression in cancer cells is regulated by transcription factor Sp1, CREB, and CpG island methylation.

Tang H, Goldberg E.

J Androl. 2009 Mar-Apr;30(2):157-67. doi: 10.2164/jandrol.108.005785. Epub 2008 Oct 16.

6.

Inactivation of p16INK4a by CpG hypermethylation is not a frequent event in colorectal cancer.

Norrie MW, Hawkins NJ, Todd AV, Meagher AP, O'Connor TW, Ward RL.

J Surg Oncol. 2003 Nov;84(3):143-50.

PMID:
14598358
7.

Relative mRNA expression of the lactate dehydrogenase A and B subunits as determined by simultaneous amplification and single strand conformation polymorphism. Relation with subunit enzyme activity.

Liu ZJ, Peng WC, Yang X, Huang JF, Zhang XB, Zhang Y, Maekawa M.

J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Aug 15;793(2):405-12.

PMID:
12906915
8.

CpG island hypermethylation is maintained in human colorectal cancer cells after RNAi-mediated depletion of DNMT1.

Ting AH, Jair KW, Suzuki H, Yen RW, Baylin SB, Schuebel KE.

Nat Genet. 2004 Jun;36(6):582-4. Epub 2004 May 23.

PMID:
15156141
9.

The lactate dehydrogenases encoded by the ldh and ldhB genes in Lactococcus lactis exhibit distinct regulation and catalytic properties - comparative modeling to probe the molecular basis.

Gaspar P, Neves AR, Shearman CA, Gasson MJ, Baptista AM, Turner DL, Soares CM, Santos H.

FEBS J. 2007 Nov;274(22):5924-36. Epub 2007 Oct 18.

10.

Decreased lactate dehydrogenase B expression enhances claudin 1-mediated hepatoma cell invasiveness via mitochondrial defects.

Kim JH, Kim EL, Lee YK, Park CB, Kim BW, Wang HJ, Yoon CH, Lee SJ, Yoon G.

Exp Cell Res. 2011 May 1;317(8):1108-18. doi: 10.1016/j.yexcr.2011.02.011. Epub 2011 Feb 26.

PMID:
21356207
11.

CIMPle origin for promoter hypermethylation in colorectal cancer?

Schuebel K, Chen W, Baylin SB.

Nat Genet. 2006 Jul;38(7):738-40. No abstract available.

PMID:
16804535
12.

MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.

Ogino S, Hazra A, Tranah GJ, Kirkner GJ, Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Meyerhardt JA, Hunter DJ, Fuchs CS.

Carcinogenesis. 2007 Sep;28(9):1985-90. Epub 2007 Jul 9.

PMID:
17621591
13.

DNA methylation, field effects, and colorectal cancer.

Giovannucci E, Ogino S.

J Natl Cancer Inst. 2005 Sep 21;97(18):1317-9. No abstract available.

PMID:
16174847
14.

Promoter hypermethylation of multiple genes in early gastric adenocarcinoma and precancerous lesions.

Zou XP, Zhang B, Zhang XQ, Chen M, Cao J, Liu WJ.

Hum Pathol. 2009 Nov;40(11):1534-42. doi: 10.1016/j.humpath.2009.01.029. Epub 2009 Aug 19.

PMID:
19695681
15.

Hypermethylation of O6-methylguanine-DNA methyltransferase promoter may predict nonrecurrence after chemotherapy in colorectal cancer cases.

Nagasaka T, Sharp GB, Notohara K, Kambara T, Sasamoto H, Isozaki H, MacPhee DG, Jass JR, Tanaka N, Matsubara N.

Clin Cancer Res. 2003 Nov 1;9(14):5306-12.

16.

DNA stool test for colorectal cancer: hypermethylation of the secreted frizzled-related protein-1 gene.

Zhang W, Bauer M, Croner RS, Pelz JO, Lodygin D, Hermeking H, St├╝rzl M, Hohenberger W, Matzel KE.

Dis Colon Rectum. 2007 Oct;50(10):1618-26; discussion 1626-7.

PMID:
17762966
17.
18.

Accumulation of DNA methylation is associated with tumor stage in gastric cancer.

Oue N, Mitani Y, Motoshita J, Matsumura S, Yoshida K, Kuniyasu H, Nakayama H, Yasui W.

Cancer. 2006 Mar 15;106(6):1250-9.

19.

Methylation-associated silencing of death-associated protein kinase gene in laryngeal squamous cell cancer.

Kong WJ, Zhang S, Guo C, Zhang S, Wang Y, Zhang D.

Laryngoscope. 2005 Aug;115(8):1395-401.

PMID:
16094112
20.

Promoter hypermethylation profile of kidney cancer.

Dulaimi E, Ibanez de Caceres I, Uzzo RG, Al-Saleem T, Greenberg RE, Polascik TJ, Babb JS, Grizzle WE, Cairns P.

Clin Cancer Res. 2004 Jun 15;10(12 Pt 1):3972-9.

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