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Items: 1 to 20 of 117

1.

Smad6 is induced by BMP-2 and modulates chondrocyte differentiation.

Li X, Ionescu AM, Schwarz EM, Zhang X, Drissi H, Puzas JE, Rosier RN, Zuscik MJ, O'Keefe RJ.

J Orthop Res. 2003 Sep;21(5):908-13.

2.

CREB Cooperates with BMP-stimulated Smad signaling to enhance transcription of the Smad6 promoter.

Ionescu AM, Drissi H, Schwarz EM, Kato M, Puzas JE, McCance DJ, Rosier RN, Zuscik MJ, O'Keefe RJ.

J Cell Physiol. 2004 Mar;198(3):428-40.

PMID:
14755548
3.

Functions of transforming growth factor-beta family type I receptors and Smad proteins in the hypertrophic maturation and osteoblastic differentiation of chondrocytes.

Valcourt U, Gouttenoire J, Moustakas A, Herbage D, Mallein-Gerin F.

J Biol Chem. 2002 Sep 13;277(37):33545-58. Epub 2002 Jun 24.

4.

Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes.

Drissi MH, Li X, Sheu TJ, Zuscik MJ, Schwarz EM, Puzas JE, Rosier RN, O'Keefe RJ.

J Cell Biochem. 2003 Dec 15;90(6):1287-98.

PMID:
14635200
5.

BMP signaling stimulates chondrocyte maturation and the expression of Indian hedgehog.

Grimsrud CD, Romano PR, D'Souza M, Puzas JE, Schwarz EM, Reynolds PR, Roiser RN, O'Keefe RJ.

J Orthop Res. 2001 Jan;19(1):18-25.

6.

5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes.

Zuscik MJ, Baden JF, Wu Q, Sheu TJ, Schwarz EM, Drissi H, O'Keefe RJ, Puzas JE, Rosier RN.

J Cell Biochem. 2004 May 15;92(2):316-31.

PMID:
15108358
8.

PTHrP expression in chick sternal chondrocytes is regulated by TGF-beta through Smad-mediated signaling.

Pateder DB, Ferguson CM, Ionescu AM, Schwarz EM, Rosier RN, Puzas JE, O'Keefe RJ.

J Cell Physiol. 2001 Sep;188(3):343-51.

PMID:
11473361
9.

Induction of Smad6 mRNA by bone morphogenetic proteins.

Takase M, Imamura T, Sampath TK, Takeda K, Ichijo H, Miyazono K, Kawabata M.

Biochem Biophys Res Commun. 1998 Mar 6;244(1):26-9.

PMID:
9514869
10.

Bone morphogenetic protein activities are enhanced by 3',5'-cyclic adenosine monophosphate through suppression of Smad6 expression in osteoprogenitor cells.

Sugama R, Koike T, Imai Y, Nomura-Furuwatari C, Takaoka K.

Bone. 2006 Feb;38(2):206-14. Epub 2005 Oct 3.

PMID:
16203197
11.

A BMP responsive transcriptional region in the chicken type X collagen gene.

Volk SW, Luvalle P, Leask T, Leboy PS.

J Bone Miner Res. 1998 Oct;13(10):1521-9.

12.
13.

Retinoic acid stimulates chondrocyte differentiation and enhances bone morphogenetic protein effects through induction of Smad1 and Smad5.

Li X, Schwarz EM, Zuscik MJ, Rosier RN, Ionescu AM, Puzas JE, Drissi H, Sheu TJ, O'Keefe RJ.

Endocrinology. 2003 Jun;144(6):2514-23.

PMID:
12746314
14.

Smad7 Inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways.

Iwai T, Murai J, Yoshikawa H, Tsumaki N.

J Biol Chem. 2008 Oct 3;283(40):27154-64. doi: 10.1074/jbc.M801175200. Epub 2008 Jul 21.

15.

Smad6 functions as an intracellular antagonist of some TGF-beta family members during Xenopus embryogenesis.

Nakayama T, Gardner H, Berg LK, Christian JL.

Genes Cells. 1998 Jun;3(6):387-94.

16.

ATF-2 cooperates with Smad3 to mediate TGF-beta effects on chondrocyte maturation.

Ionescu AM, Schwarz EM, Zuscik MJ, Drissi H, Puzas JE, Rosier RN, O'Keefe RJ.

Exp Cell Res. 2003 Aug 1;288(1):198-207.

PMID:
12878171
17.

BMP-6 is an autocrine stimulator of chondrocyte differentiation.

Grimsrud CD, Romano PR, D'Souza M, Puzas JE, Reynolds PR, Rosier RN, O'Keefe RJ.

J Bone Miner Res. 1999 Apr;14(4):475-82.

18.

Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor.

Dong YF, Soung do Y, Schwarz EM, O'Keefe RJ, Drissi H.

J Cell Physiol. 2006 Jul;208(1):77-86.

PMID:
16575901
19.

Bone morphogenetic protein signaling in articular chondrocyte differentiation.

Nishihara A, Fujii M, Sampath TK, Miyazono K, Reddi AH.

Biochem Biophys Res Commun. 2003 Feb 7;301(2):617-22.

PMID:
12565908
20.

Bone morphogenetic protein-2 inhibits serum deprivation-induced apoptosis of neonatal cardiac myocytes through activation of the Smad1 pathway.

Izumi M, Fujio Y, Kunisada K, Negoro S, Tone E, Funamoto M, Osugi T, Oshima Y, Nakaoka Y, Kishimoto T, Yamauchi-Takihara K, Hirota H.

J Biol Chem. 2001 Aug 17;276(33):31133-41. Epub 2001 Jun 14.

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