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Items: 1 to 20 of 656

1.

Transgenic rat hearts overexpressing SERCA2a show improved contractility under baseline conditions and pressure overload.

Müller OJ, Lange M, Rattunde H, Lorenzen HP, Müller M, Frey N, Bittner C, Simonides W, Katus HA, Franz WM.

Cardiovasc Res. 2003 Aug 1;59(2):380-9.

PMID:
12909321
2.

Overexpression of the sarcoplasmic reticulum Ca(2+)-ATPase improves myocardial contractility in diabetic cardiomyopathy.

Trost SU, Belke DD, Bluhm WF, Meyer M, Swanson E, Dillmann WH.

Diabetes. 2002 Apr;51(4):1166-71.

3.

[Treatment of chronic heart failure by overexpressing sarcoplasmic reticulum calcium ATPase through gene therapy: an experiment with rats].

Li XY, Hui HP, Lu XC, Guo YT.

Zhonghua Yi Xue Za Zhi. 2006 May 9;86(17):1174-8. Chinese.

PMID:
16796857
4.

Increased SR Ca2+ cycling contributes to improved contractile performance in SERCA2a-overexpressing transgenic rats.

Maier LS, Wahl-Schott C, Horn W, Weichert S, Pagel C, Wagner S, Dybkova N, Müller OJ, Näbauer M, Franz WM, Pieske B.

Cardiovasc Res. 2005 Sep 1;67(4):636-46.

PMID:
15932750
5.

Restoration of diastolic function in senescent rat hearts through adenoviral gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase.

Schmidt U, del Monte F, Miyamoto MI, Matsui T, Gwathmey JK, Rosenzweig A, Hajjar RJ.

Circulation. 2000 Feb 22;101(7):790-6.

6.

Doxycycline inducible expression of SERCA2a improves calcium handling and reverts cardiac dysfunction in pressure overload-induced cardiac hypertrophy.

Suarez J, Gloss B, Belke DD, Hu Y, Scott B, Dieterle T, Kim YK, Valencik ML, McDonald JA, Dillmann WH.

Am J Physiol Heart Circ Physiol. 2004 Nov;287(5):H2164-72. Epub 2004 Jul 15.

PMID:
15256372
7.

Targeted overexpression of the sarcoplasmic reticulum Ca2+-ATPase increases cardiac contractility in transgenic mouse hearts.

Baker DL, Hashimoto K, Grupp IL, Ji Y, Reed T, Loukianov E, Grupp G, Bhagwhat A, Hoit B, Walsh R, Marban E, Periasamy M.

Circ Res. 1998 Dec 14-28;83(12):1205-14.

8.

Comparative analysis of parvalbumin and SERCA2a cardiac myocyte gene transfer in a large animal model of diastolic dysfunction.

Hirsch JC, Borton AR, Albayya FP, Russell MW, Ohye RG, Metzger JM.

Am J Physiol Heart Circ Physiol. 2004 Jun;286(6):H2314-21.

PMID:
15148059
9.

[Adeno-associated viral gene transfer of SERCA2a improves heart function in chronic congestive heart failure rats].

Hui HP, Li XY, Liu XH, Sun S, Lu XC, Liu T, Yang W.

Zhonghua Xin Xue Guan Bing Za Zhi. 2006 Apr;34(4):357-62. Chinese.

PMID:
16776934
10.

Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure.

Kawase Y, Ly HQ, Prunier F, Lebeche D, Shi Y, Jin H, Hadri L, Yoneyama R, Hoshino K, Takewa Y, Sakata S, Peluso R, Zsebo K, Gwathmey JK, Tardif JC, Tanguay JF, Hajjar RJ.

J Am Coll Cardiol. 2008 Mar 18;51(11):1112-9. doi: 10.1016/j.jacc.2007.12.014.

11.

Improvement in cardiac function after sarcoplasmic reticulum Ca2+-ATPase gene transfer in a beagle heart failure model.

Mi YF, Li XY, Tang LJ, Lu XC, Fu ZQ, Ye WH.

Chin Med J (Engl). 2009 Jun 20;122(12):1423-8.

PMID:
19567165
12.

Compromised myocardial energetics in hypertrophied mouse hearts diminish the beneficial effect of overexpressing SERCA2a.

Pinz I, Tian R, Belke D, Swanson E, Dillmann W, Ingwall JS.

J Biol Chem. 2011 Mar 25;286(12):10163-8. doi: 10.1074/jbc.M110.210757. Epub 2011 Jan 29.

13.

Enhanced myocardial contractility and increased Ca2+ transport function in transgenic hearts expressing the fast-twitch skeletal muscle sarcoplasmic reticulum Ca2+-ATPase.

Loukianov E, Ji Y, Grupp IL, Kirkpatrick DL, Baker DL, Loukianova T, Grupp G, Lytton J, Walsh RA, Periasamy M.

Circ Res. 1998 Nov 2;83(9):889-97.

14.

Sarcoplasmic reticulum Ca2+-ATPase modulates cardiac contraction and relaxation.

Frank KF, Bölck B, Erdmann E, Schwinger RH.

Cardiovasc Res. 2003 Jan;57(1):20-7. Review.

PMID:
12504810
15.

[Overexpression of sarcoplasmic reticulum calcium ATPase induced hemodynamic and proteomic changes in a dog model of heart failure].

Fu ZQ, Li XY, Liu XH, Sun S, Liu T, Mi YF, Zhou SA, Ye WH, Wang QS.

Zhonghua Xin Xue Guan Bing Za Zhi. 2008 Mar;36(3):260-5. Chinese.

PMID:
19099986
16.

Rescue of Ca2+ overload-induced left ventricular dysfunction by targeted ablation of phospholamban.

Tsuji T, Del Monte F, Yoshikawa Y, Abe T, Shimizu J, Nakajima-Takenaka C, Taniguchi S, Hajjar RJ, Takaki M.

Am J Physiol Heart Circ Physiol. 2009 Feb;296(2):H310-7. doi: 10.1152/ajpheart.00975.2008. Epub 2008 Dec 12.

PMID:
19074672
17.

Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure.

Miyamoto MI, del Monte F, Schmidt U, DiSalvo TS, Kang ZB, Matsui T, Guerrero JL, Gwathmey JK, Rosenzweig A, Hajjar RJ.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):793-8.

18.
19.

SERCA2A overexpression decreases the incidence of aftercontractions in adult rabbit ventricular myocytes.

Davia K, Bernobich E, Ranu HK, del Monte F, Terracciano CM, MacLeod KT, Adamson DL, Chaudhri B, Hajjar RJ, Harding SE.

J Mol Cell Cardiol. 2001 May;33(5):1005-15.

PMID:
11343422
20.

Overexpression of SERCA2b in the heart leads to an increase in sarcoplasmic reticulum calcium transport function and increased cardiac contractility.

Greene AL, Lalli MJ, Ji Y, Babu GJ, Grupp I, Sussman M, Periasamy M.

J Biol Chem. 2000 Aug 11;275(32):24722-7.

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