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Items: 1 to 20 of 136


Vav1 dephosphorylation by the tyrosine phosphatase SHP-1 as a mechanism for inhibition of cellular cytotoxicity.

Stebbins CC, Watzl C, Billadeau DD, Leibson PJ, Burshtyn DN, Long EO.

Mol Cell Biol. 2003 Sep;23(17):6291-9.


Spontaneous clustering and tyrosine phosphorylation of NK cell inhibitory receptor induced by ligand binding.

Faure M, Barber DF, Takahashi SM, Jin T, Long EO.

J Immunol. 2003 Jun 15;170(12):6107-14.


LFA-1 contributes an early signal for NK cell cytotoxicity.

Barber DF, Faure M, Long EO.

J Immunol. 2004 Sep 15;173(6):3653-9.


F-actin dynamics control segregation of the TCR signaling cascade to clustered lipid rafts.

Valensin S, Paccani SR, Ulivieri C, Mercati D, Pacini S, Patrussi L, Hirst T, Lupetti P, Baldari CT.

Eur J Immunol. 2002 Feb;32(2):435-46.


CD94/NKG2A inhibits NK cell activation by disrupting the actin network at the immunological synapse.

Masilamani M, Nguyen C, Kabat J, Borrego F, Coligan JE.

J Immunol. 2006 Sep 15;177(6):3590-6.


Elucidation of the integrin LFA-1-mediated signaling pathway of actin polarization in natural killer cells.

Mace EM, Zhang J, Siminovitch KA, Takei F.

Blood. 2010 Aug 26;116(8):1272-9. doi: 10.1182/blood-2009-12-261487.


In contrast to anti-tumor activity, YT cell and primary NK cell cytotoxicity for Cryptococcus neoformans bypasses LFA-1.

Jones GJ, Wiseman JC, Marr KJ, Wei S, Djeu JY, Mody CH.

Int Immunol. 2009 Apr;21(4):423-32. doi: 10.1093/intimm/dxp010.


Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells.

Villalba M, Bi K, Rodriguez F, Tanaka Y, Schoenberger S, Altman A.

J Cell Biol. 2001 Oct 29;155(3):331-8.


Activation of natural killer cell migration by leukocyte integrin-binding peptide from intracellular adhesion molecule-2 (ICAM-2).

Somersalo K, Carpén O, Saksela E, Gahmberg CG, Nortamo P, Timonen T.

J Biol Chem. 1995 Apr 14;270(15):8629-36.


Vav1 controls DAP10-mediated natural cytotoxicity by regulating actin and microtubule dynamics.

Graham DB, Cella M, Giurisato E, Fujikawa K, Miletic AV, Kloeppel T, Brim K, Takai T, Shaw AS, Colonna M, Swat W.

J Immunol. 2006 Aug 15;177(4):2349-55.


Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects.

Paccani SR, Boncristiano M, Patrussi L, Ulivieri C, Wack A, Valensin S, Hirst TR, Amedei A, Del Prete G, Telford JL, D'Elios MM, Baldari CT.

Blood. 2005 Jul 15;106(2):626-34.


Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1.

Miranti CK, Leng L, Maschberger P, Brugge JS, Shattil SJ.

Curr Biol. 1998 Dec 3;8(24):1289-99.


Tethering of intercellular adhesion molecule on target cells is required for LFA-1-dependent NK cell adhesion and granule polarization.

Gross CC, Brzostowski JA, Liu D, Long EO.

J Immunol. 2010 Sep 1;185(5):2918-26. doi: 10.4049/jimmunol.1000761.

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