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Items: 1 to 20 of 95

1.

Human T-cell leukemia virus-I tax oncoprotein functionally targets a subnuclear complex involved in cellular DNA damage-response.

Haoudi A, Daniels RC, Wong E, Kupfer G, Semmes OJ.

J Biol Chem. 2003 Sep 26;278(39):37736-44. Epub 2003 Jul 2.

2.

53BP1, a mediator of the DNA damage checkpoint.

Wang B, Matsuoka S, Carpenter PB, Elledge SJ.

Science. 2002 Nov 15;298(5597):1435-8. Epub 2002 Oct 3.

3.
4.

MDC1 is a mediator of the mammalian DNA damage checkpoint.

Stewart GS, Wang B, Bignell CR, Taylor AM, Elledge SJ.

Nature. 2003 Feb 27;421(6926):961-6.

PMID:
12607005
5.

HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase.

Durkin SS, Guo X, Fryrear KA, Mihaylova VT, Gupta SK, Belgnaoui SM, Haoudi A, Kupfer GM, Semmes OJ.

J Biol Chem. 2008 Dec 26;283(52):36311-20. doi: 10.1074/jbc.M804931200. Epub 2008 Oct 27.

6.

Human T-cell leukemia virus type 1 Tax oncoprotein prevents DNA damage-induced chromatin egress of hyperphosphorylated Chk2.

Gupta SK, Guo X, Durkin SS, Fryrear KF, Ward MD, Semmes OJ.

J Biol Chem. 2007 Oct 5;282(40):29431-40. Epub 2007 Aug 13.

7.

Human T-cell leukemia virus type 1 Tax interacts with Chk1 and attenuates DNA-damage induced G2 arrest mediated by Chk1.

Park HU, Jeong JH, Chung JH, Brady JN.

Oncogene. 2004 Jun 24;23(29):4966-74.

PMID:
15107832
8.

The p53-inducible gene 3 (PIG3) contributes to early cellular response to DNA damage.

Lee JH, Kang Y, Khare V, Jin ZY, Kang MY, Yoon Y, Hyun JW, Chung MH, Cho SI, Jun JY, Chang IY, You HJ.

Oncogene. 2010 Mar 11;29(10):1431-50. doi: 10.1038/onc.2009.438. Epub 2009 Dec 21.

PMID:
20023697
9.

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.

Fernandez-Capetillo O, Chen HT, Celeste A, Ward I, Romanienko PJ, Morales JC, Naka K, Xia Z, Camerini-Otero RD, Motoyama N, Carpenter PB, Bonner WM, Chen J, Nussenzweig A.

Nat Cell Biol. 2002 Dec;4(12):993-7.

PMID:
12447390
10.

Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2.

Adamson AW, Beardsley DI, Kim WJ, Gao Y, Baskaran R, Brown KD.

Mol Biol Cell. 2005 Mar;16(3):1513-26. Epub 2005 Jan 12.

11.

Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding.

Hein J, Boichuk S, Wu J, Cheng Y, Freire R, Jat PS, Roberts TM, Gjoerup OV.

J Virol. 2009 Jan;83(1):117-27. doi: 10.1128/JVI.01515-08. Epub 2008 Oct 15.

12.

CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses.

Yan T, Desai AB, Jacobberger JW, Sramkoski RM, Loh T, Kinsella TJ.

Mol Cancer Ther. 2004 Sep;3(9):1147-57.

13.

Human T-cell leukemia virus type 1 Tax attenuates gamma-irradiation-induced apoptosis through physical interaction with Chk2.

Park HU, Jeong SJ, Jeong JH, Chung JH, Brady JN.

Oncogene. 2006 Jan 19;25(3):438-47.

PMID:
16158050
14.

A DNA damage checkpoint response in telomere-initiated senescence.

d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G, Carter NP, Jackson SP.

Nature. 2003 Nov 13;426(6963):194-8. Epub 2003 Nov 5.

PMID:
14608368
15.
16.

ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis.

Pabla N, Huang S, Mi QS, Daniel R, Dong Z.

J Biol Chem. 2008 Mar 7;283(10):6572-83. Epub 2007 Dec 27. Erratum in: J Biol Chem. 2008 May 30;283(22):15512.

17.

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer.

DiTullio RA Jr, Mochan TA, Venere M, Bartkova J, Sehested M, Bartek J, Halazonetis TD.

Nat Cell Biol. 2002 Dec;4(12):998-1002. Erratum in: Nat Cell Biol. 2003 Jan;5(1):84..

PMID:
12447382
18.

Human T-cell leukemia virus type 1 tax attenuates the ATM-mediated cellular DNA damage response.

Chandhasin C, Ducu RI, Berkovich E, Kastan MB, Marriott SJ.

J Virol. 2008 Jul;82(14):6952-61. doi: 10.1128/JVI.02331-07. Epub 2008 Apr 23.

19.

Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.

Gatei M, Sloper K, Sorensen C, Syljuäsen R, Falck J, Hobson K, Savage K, Lukas J, Zhou BB, Bartek J, Khanna KK.

J Biol Chem. 2003 Apr 25;278(17):14806-11. Epub 2003 Feb 14.

20.

A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint.

van Vugt MA, Gardino AK, Linding R, Ostheimer GJ, Reinhardt HC, Ong SE, Tan CS, Miao H, Keezer SM, Li J, Pawson T, Lewis TA, Carr SA, Smerdon SJ, Brummelkamp TR, Yaffe MB.

PLoS Biol. 2010 Jan 26;8(1):e1000287. doi: 10.1371/journal.pbio.1000287.

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