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Items: 1 to 20 of 86

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Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo.

Shih AY, Imbeault S, Barakauskas V, Erb H, Jiang L, Li P, Murphy TH.

J Biol Chem. 2005 Jun 17;280(24):22925-36. Epub 2005 Apr 19.

4.

Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress.

Leung L, Kwong M, Hou S, Lee C, Chan JY.

J Biol Chem. 2003 Nov 28;278(48):48021-9. Epub 2003 Sep 10.

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An important role of Nrf2-ARE pathway in the cellular defense mechanism.

Lee JM, Johnson JA.

J Biochem Mol Biol. 2004 Mar 31;37(2):139-43. Review.

PMID:
15469687
7.

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.

Itoh K, Chiba T, Takahashi S, Ishii T, Igarashi K, Katoh Y, Oyake T, Hayashi N, Satoh K, Hatayama I, Yamamoto M, Nabeshima Y.

Biochem Biophys Res Commun. 1997 Jul 18;236(2):313-22.

PMID:
9240432
10.

Neuronal sensitivity to kainic acid is dependent on the Nrf2-mediated actions of the antioxidant response element.

Kraft AD, Lee JM, Johnson DA, Kan YW, Johnson JA.

J Neurochem. 2006 Sep;98(6):1852-65.

11.

Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones.

Pietsch EC, Chan JY, Torti FM, Torti SV.

J Biol Chem. 2003 Jan 24;278(4):2361-9. Epub 2002 Nov 14.

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Nrf2 activation involves an oxidative-stress independent pathway in tetrafluoroethylcysteine-induced cytotoxicity.

Ho HK, White CC, Fernandez C, Fausto N, Kavanagh TJ, Nelson SD, Bruschi SA.

Toxicol Sci. 2005 Aug;86(2):354-64. Epub 2005 May 18.

PMID:
15901913
14.

NADPH oxidase and ERK signaling regulates hyperoxia-induced Nrf2-ARE transcriptional response in pulmonary epithelial cells.

Papaiahgari S, Kleeberger SR, Cho HY, Kalvakolanu DV, Reddy SP.

J Biol Chem. 2004 Oct 1;279(40):42302-12. Epub 2004 Jul 29.

16.

The Nrf2-ARE cytoprotective pathway in astrocytes.

Vargas MR, Johnson JA.

Expert Rev Mol Med. 2009 Jun 3;11:e17. doi: 10.1017/S1462399409001094. Review.

PMID:
19490732
17.

Ascorbic acid restores sensitivity to imatinib via suppression of Nrf2-dependent gene expression in the imatinib-resistant cell line.

Tarumoto T, Nagai T, Ohmine K, Miyoshi T, Nakamura M, Kondo T, Mitsugi K, Nakano S, Muroi K, Komatsu N, Ozawa K.

Exp Hematol. 2004 Apr;32(4):375-81.

PMID:
15050748
18.

Dietary flavonoid (-)epicatechin stimulates phosphatidylinositol 3-kinase-dependent anti-oxidant response element activity and up-regulates glutathione in cortical astrocytes.

Bahia PK, Rattray M, Williams RJ.

J Neurochem. 2008 Sep;106(5):2194-204. doi: 10.1111/j.1471-4159.2008.05542.x. Epub 2008 Jul 4.

19.

Gene expression profiling of NRF2-mediated protection against oxidative injury.

Cho HY, Reddy SP, Debiase A, Yamamoto M, Kleeberger SR.

Free Radic Biol Med. 2005 Feb 1;38(3):325-43.

PMID:
15629862
20.

Nrf2 and antioxidant defense against CYP2E1 toxicity.

Cederbaum A.

Expert Opin Drug Metab Toxicol. 2009 Oct;5(10):1223-44. doi: 10.1517/17425250903143769. Review.

PMID:
19671018

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