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Items: 1 to 20 of 192

1.

From pro defensins to defensins: synthesis and characterization of human neutrophil pro alpha-defensin-1 and its mature domain.

Wu Z, Prahl A, Powell R, Ericksen B, Lubkowski J, Lu W.

J Pept Res. 2003 Aug;62(2):53-62.

PMID:
12823617
2.

Productive folding of human neutrophil alpha-defensins in vitro without the pro-peptide.

Wu Z, Powell R, Lu W.

J Am Chem Soc. 2003 Mar 5;125(9):2402-3.

PMID:
12603122
3.

Impact of pro segments on the folding and function of human neutrophil alpha-defensins.

Wu Z, Li X, Ericksen B, de Leeuw E, Zou G, Zeng P, Xie C, Li C, Lubkowski J, Lu WY, Lu W.

J Mol Biol. 2007 Apr 27;368(2):537-49. Epub 2007 Feb 22.

4.

Why is the Arg5-Glu13 salt bridge conserved in mammalian alpha-defensins?

Wu Z, Li X, de Leeuw E, Ericksen B, Lu W.

J Biol Chem. 2005 Dec 30;280(52):43039-47. Epub 2005 Oct 24.

5.

Chemical synthesis, characterization and activity of RK-1, a novel alpha-defensin-related peptide.

Dawson NF, Craik DJ, McManus AM, Dashper SG, Reynolds EC, Tregear GW, Otvos L Jr, Wade JD.

J Pept Sci. 2000 Jan;6(1):19-25.

PMID:
10674716
6.

High fidelity processing and activation of the human α-defensin HNP1 precursor by neutrophil elastase and proteinase 3.

Tongaonkar P, Golji AE, Tran P, Ouellette AJ, Selsted ME.

PLoS One. 2012;7(3):e32469. doi: 10.1371/journal.pone.0032469. Epub 2012 Mar 20.

7.

Denatured human alpha-defensin attenuates the bactericidal activity and the stability against enzymatic digestion.

Tanabe H, Ayabe T, Maemoto A, Ishikawa C, Inaba Y, Sato R, Moriichi K, Okamoto K, Watari J, Kono T, Ashida T, Kohgo Y.

Biochem Biophys Res Commun. 2007 Jun 22;358(1):349-55. Epub 2007 Apr 30.

PMID:
17482139
8.

Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.

Xie C, Prahl A, Ericksen B, Wu Z, Zeng P, Li X, Lu WY, Lubkowski J, Lu W.

J Biol Chem. 2005 Sep 23;280(38):32921-9. Epub 2005 May 13.

9.

Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3.

Wu Z, Hoover DM, Yang D, Boulègue C, Santamaria F, Oppenheim JJ, Lubkowski J, Lu W.

Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8880-5. Epub 2003 Jul 2.

10.
11.

Molecular determinants for the interaction of human neutrophil alpha defensin 1 with its propeptide.

Zou G, de Leeuw E, Lubkowski J, Lu W.

J Mol Biol. 2008 Sep 19;381(5):1281-91. doi: 10.1016/j.jmb.2008.06.066. Epub 2008 Jun 28.

13.

Isolation and sequence determination of 6- and 8-kDa precursors of human neutrophil peptides from bone marrow, plasma and peripheral blood neutrophils.

Nakazato M, Shiomi K, Date Y, Matsukura S, Kangawa K, Minamino N, Matsuo H.

Biochem Biophys Res Commun. 1995 Jun 26;211(3):1053-62.

PMID:
7598692
14.

Characterization of defensin precursors in mature human neutrophils.

Harwig SS, Park AS, Lehrer RI.

Blood. 1992 Mar 15;79(6):1532-7.

15.

Differential Processing of {alpha}- and {beta}-Defensin Precursors by Matrix Metalloproteinase-7 (MMP-7).

Wilson CL, Schmidt AP, Pirilä E, Valore EV, Ferri N, Sorsa T, Ganz T, Parks WC.

J Biol Chem. 2009 Mar 27;284(13):8301-11. doi: 10.1074/jbc.M809744200. Epub 2009 Jan 30.

16.
17.

Engineered salt-insensitive alpha-defensins with end-to-end circularized structures.

Yu Q, Lehrer RI, Tam JP.

J Biol Chem. 2000 Feb 11;275(6):3943-9.

18.

Synthesis and characterization of human alpha-defensins 4-6.

Wu Z, Ericksen B, Tucker K, Lubkowski J, Lu W.

J Pept Res. 2004 Sep;64(3):118-25.

PMID:
15317502
19.

Prodefensins are matrix proteins of specific granules in human neutrophils.

Faurschou M, Kamp S, Cowland JB, Udby L, Johnsen AH, Calafat J, Winther H, Borregaard N.

J Leukoc Biol. 2005 Sep;78(3):785-93. Epub 2005 Jun 8.

PMID:
15944211
20.

Human antimicrobial peptides: defensins, cathelicidins and histatins.

De Smet K, Contreras R.

Biotechnol Lett. 2005 Sep;27(18):1337-47. Review.

PMID:
16215847

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