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Items: 1 to 20 of 117


The Bcr kinase downregulates Ras signaling by phosphorylating AF-6 and binding to its PDZ domain.

Radziwill G, Erdmann RA, Margelisch U, Moelling K.

Mol Cell Biol. 2003 Jul;23(13):4663-72.


Solution structure and backbone dynamics of the AF-6 PDZ domain/Bcr peptide complex.

Chen Q, Niu X, Xu Y, Wu J, Shi Y.

Protein Sci. 2007 Jun;16(6):1053-62. Epub 2007 May 1.


Solution structure of AF-6 PDZ domain and its interaction with the C-terminal peptides from Neurexin and Bcr.

Zhou H, Xu Y, Yang Y, Huang A, Wu J, Shi Y.

J Biol Chem. 2005 Apr 8;280(14):13841-7. Epub 2005 Jan 31.


Regulation of c-Src by binding to the PDZ domain of AF-6.

Radziwill G, Weiss A, Heinrich J, Baumgartner M, Boisguerin P, Owada K, Moelling K.

EMBO J. 2007 Jun 6;26(11):2633-44. Epub 2007 May 10.


Role of Dok1 in cell signaling mediated by RET tyrosine kinase.

Murakami H, Yamamura Y, Shimono Y, Kawai K, Kurokawa K, Takahashi M.

J Biol Chem. 2002 Sep 6;277(36):32781-90. Epub 2002 Jun 26.


An oncogenic epidermal growth factor receptor signals via a p21-activated kinase-caldesmon-myosin phosphotyrosine complex.

McManus MJ, Boerner JL, Danielsen AJ, Wang Z, Matsumura F, Maihle NJ.

J Biol Chem. 2000 Nov 10;275(45):35328-34.


p160 Bcr mediates platelet-derived growth factor activation of extracellular signal-regulated kinase in vascular smooth muscle cells.

Che W, Abe J, Yoshizumi M, Huang Q, Glassman M, Ohta S, Melaragno MG, Poppa V, Yan C, Lerner-Marmarosh N, Zhang C, Wu Y, Arlinghaus R, Berk BC.

Circulation. 2001 Sep 18;104(12):1399-406.


The role of Hsp90N, a new member of the Hsp90 family, in signal transduction and neoplastic transformation.

Grammatikakis N, Vultur A, Ramana CV, Siganou A, Schweinfest CW, Watson DK, Raptis L.

J Biol Chem. 2002 Mar 8;277(10):8312-20. Epub 2001 Dec 20.


Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway.

Bassermann F, Jahn T, Miething C, Seipel P, Bai RY, Coutinho S, Tybulewicz VL, Peschel C, Duyster J.

J Biol Chem. 2002 Apr 5;277(14):12437-45. Epub 2002 Jan 14.


A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid.

Yart A, Roche S, Wetzker R, Laffargue M, Tonks N, Mayeux P, Chap H, Raynal P.

J Biol Chem. 2002 Jun 14;277(24):21167-78. Epub 2002 Mar 26.


Interesting structural and dynamical behaviors exhibited by the AF-6 PDZ domain upon Bcr peptide binding.

Niu X, Chen Q, Zhang J, Shen W, Shi Y, Wu J.

Biochemistry. 2007 Dec 25;46(51):15042-53. Epub 2007 Dec 4.


Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling.

Liang X, Wisniewski D, Strife A, Shivakrupa, Clarkson B, Resh MD.

J Biol Chem. 2002 Apr 19;277(16):13732-8. Epub 2002 Feb 1.


Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation.

Harada J, Kokura K, Kanei-Ishii C, Nomura T, Khan MM, Kim Y, Ishii S.

J Biol Chem. 2003 Oct 3;278(40):38998-9005. Epub 2003 Jul 21.


Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1.

Ebnet K, Schulz CU, Meyer Zu Brickwedde MK, Pendl GG, Vestweber D.

J Biol Chem. 2000 Sep 8;275(36):27979-88.

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