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Activation of the Arp2/3 complex by N-WASp is required for actin polymerization and contraction in smooth muscle.

Zhang W, Wu Y, Du L, Tang DD, Gunst SJ.

Am J Physiol Cell Physiol. 2005 May;288(5):C1145-60. Epub 2004 Dec 29.


Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP.

Martinez-Quiles N, Ho HY, Kirschner MW, Ramesh N, Geha RS.

Mol Cell Biol. 2004 Jun;24(12):5269-80.


Interaction of cortactin and N-WASp with Arp2/3 complex.

Weaver AM, Heuser JE, Karginov AV, Lee WL, Parsons JT, Cooper JA.

Curr Biol. 2002 Aug 6;12(15):1270-8.


A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42.

Fukuoka M, Suetsugu S, Miki H, Fukami K, Endo T, Takenawa T.

J Cell Biol. 2001 Feb 5;152(3):471-82.


Different WASP family proteins stimulate different Arp2/3 complex-dependent actin-nucleating activities.

Zalevsky J, Lempert L, Kranitz H, Mullins RD.

Curr Biol. 2001 Dec 11;11(24):1903-13.


The verprolin-like central (vc) region of Wiskott-Aldrich syndrome protein induces Arp2/3 complex-dependent actin nucleation.

H├╝fner K, Higgs HN, Pollard TD, Jacobi C, Aepfelbacher M, Linder S.

J Biol Chem. 2001 Sep 21;276(38):35761-7. Epub 2001 Jul 17.


Enhancement of branching efficiency by the actin filament-binding activity of N-WASP/WAVE2.

Suetsugu S, Miki H, Yamaguchi H, Obinata T, Takenawa T.

J Cell Sci. 2001 Dec;114(Pt 24):4533-42.


Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3.

Rozelle AL, Machesky LM, Yamamoto M, Driessens MH, Insall RH, Roth MG, Luby-Phelps K, Marriott G, Hall A, Yin HL.

Curr Biol. 2000 Mar 23;10(6):311-20.


Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp2/3 complex on actin polymerization.

Higgs HN, Blanchoin L, Pollard TD.

Biochemistry. 1999 Nov 16;38(46):15212-22.


Interaction of HSP90 to N-WASP leads to activation and protection from proteasome-dependent degradation.

Park SJ, Suetsugu S, Takenawa T.

EMBO J. 2005 Apr 20;24(8):1557-70. Epub 2005 Mar 24.


GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex.

Carlier MF, Nioche P, Broutin-L'Hermite I, Boujemaa R, Le Clainche C, Egile C, Garbay C, Ducruix A, Sansonetti P, Pantaloni D.

J Biol Chem. 2000 Jul 21;275(29):21946-52.


Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex.

Prehoda KE, Scott JA, Mullins RD, Lim WA.

Science. 2000 Oct 27;290(5492):801-6.

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