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Items: 1 to 20 of 102

1.

Improved in planta expression of the human islet autoantigen glutamic acid decarboxylase (GAD65).

Avesani L, Falorni A, Tornielli GB, Marusic C, Porceddu A, Polverari A, Faleri C, Calcinaro F, Pezzotti M.

Transgenic Res. 2003 Apr;12(2):203-12.

PMID:
12739888
2.

Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets.

Kim J, Richter W, Aanstoot HJ, Shi Y, Fu Q, Rajotte R, Warnock G, Baekkeskov S.

Diabetes. 1993 Dec;42(12):1799-808.

PMID:
8243826
3.

Induction of oral tolerance to prevent diabetes with transgenic plants requires glutamic acid decarboxylase (GAD) and IL-4.

Ma S, Huang Y, Yin Z, Menassa R, Brandle JE, Jevnikar AM.

Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5680-5. Epub 2004 Mar 31.

4.

Identification of glutamic acid decarboxylase autoantibody heterogeneity and epitope regions in type I diabetes.

Ujihara N, Daw K, Gianani R, Boel E, Yu L, Powers AC.

Diabetes. 1994 Aug;43(8):968-75.

PMID:
8039604
5.

Autoantibodies in IDDM primarily recognize the 65,000-M(r) rather than the 67,000-M(r) isoform of glutamic acid decarboxylase.

Hagopian WA, Michelsen B, Karlsen AE, Larsen F, Moody A, Grubin CE, Rowe R, Petersen J, McEvoy R, Lernmark A.

Diabetes. 1993 Apr;42(4):631-6.

PMID:
8454115
6.

Differential protection in two transgenic lines of NOD/Lt mice hyperexpressing the autoantigen GAD65 in pancreatic beta-cells.

Bridgett M, Cetkovic-Cvrlje M, O'Rourke R, Shi Y, Narayanswami S, Lambert J, Ramiya V, Baekkeskov S, Leiter EH.

Diabetes. 1998 Dec;47(12):1848-56.

PMID:
9836515
7.

Recombinant human GAD65 accumulates to high levels in transgenic tobacco plants when expressed as an enzymatically inactive mutant.

Avesani L, Vitale A, Pedrazzini E, Devirgilio M, Pompa A, Barbante A, Gecchele E, Dominici P, Morandini F, Brozzetti A, Falorni A, Pezzotti M.

Plant Biotechnol J. 2010 Oct;8(8):862-72. doi: 10.1111/j.1467-7652.2010.00514.x.

8.

Glutamic acid decarboxylase-67 (GAD67): expression relative to GAD65 in human islets and mapping of autoantibody epitopes.

Cram DS, Faulkner-Jones B, Kun J, Harrison LC.

Endocrinology. 1995 Mar;136(3):1111-9.

PMID:
7532577
9.

Baculovirus-mediated expression of human 65 kDa and 67 kDa glutamic acid decarboxylases in SF9 insect cells and their relevance in diagnosis of insulin-dependent diabetes mellitus.

Mauch L, Seissler J, Haubruck H, Cook NJ, Abney CC, Berthold H, Wirbelauer C, Liedvogel B, Scherbaum WA, Northemann W.

J Biochem. 1993 Jun;113(6):699-704.

10.
11.

Processing and presentation of the islet autoantigen GAD by vascular endothelial cells promotes transmigration of autoreactive T-cells.

Greening JE, Tree TI, Kotowicz KT, van Halteren AG, Roep BO, Klein NJ, Peakman M.

Diabetes. 2003 Mar;52(3):717-25.

12.

Molecular cloning of full-length glutamic acid decarboxylase 67 from human pancreas and islets.

Yamashita K, Cram DS, Harrison LC.

Biochem Biophys Res Commun. 1993 May 14;192(3):1347-52.

PMID:
8507202
13.

Detection of GAD65 antibodies in diabetes and other autoimmune diseases using a simple radioligand assay.

Petersen JS, Hejnaes KR, Moody A, Karlsen AE, Marshall MO, Høier-Madsen M, Boel E, Michelsen BK, Dyrberg T.

Diabetes. 1994 Mar;43(3):459-67.

PMID:
8314020
15.

Transgenic plants expressing autoantigens fed to mice to induce oral immune tolerance.

Ma SW, Zhao DL, Yin ZQ, Mukherjee R, Singh B, Qin HY, Stiller CR, Jevnikar AM.

Nat Med. 1997 Jul;3(7):793-6.

PMID:
9212110
16.

Murine monoclonal glutamic acid decarboxylase (GAD)65 antibodies recognize autoimmune-associated GAD epitope regions targeted in patients with type 1 diabetes mellitus and stiff-man syndrome.

Ziegler B, Schlosser M, Lühder F, Strebelow M, Augstein P, Northemann W, Powers AC, Ziegler M.

Acta Diabetol. 1996 Sep;33(3):225-31.

PMID:
8904930
17.

Non-food/feed seeds as biofactories for the high-yield production of recombinant pharmaceuticals.

Morandini F, Avesani L, Bortesi L, Van Droogenbroeck B, De Wilde K, Arcalis E, Bazzoni F, Santi L, Brozzetti A, Falorni A, Stoger E, Depicker A, Pezzotti M.

Plant Biotechnol J. 2011 Oct;9(8):911-21. doi: 10.1111/j.1467-7652.2011.00605.x. Epub 2011 Apr 11.

18.

Evaluation of a novel radioimmunoassay using 125I-labelled human recombinant GAD65 for the determination of glutamic acid decarboxylase (GAD65) autoantibodies.

Marcovina SM, Landin-Olsson M, Essen-Möller A, Palmer JP, Lernmark A.

Int J Clin Lab Res. 2000;30(1):21-6.

PMID:
10984128
19.

Cloning and expression of large isoform of glutamic acid decarboxylase from human pancreatic islet.

Kawasaki E, Moriuchi R, Watanabe M, Saitoh K, Brunicardi FC, Watt PC, Yamaguchi T, Mullen Y, Akazawa S, Miyamoto T, et al.

Biochem Biophys Res Commun. 1993 May 14;192(3):1353-9.

PMID:
8507203
20.

Recombinant glutamic acid decarboxylase (representing the single isoform expressed in human islets) detects IDDM-associated 64,000-M(r) autoantibodies.

Karlsen AE, Hagopian WA, Petersen JS, Boel E, Dyrberg T, Grubin CE, Michelsen BK, Madsen OD, Lernmark A.

Diabetes. 1992 Oct;41(10):1355-9.

PMID:
1397711

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