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Items: 1 to 20 of 156

1.

Indole-3-carbinol and 3,3'-diindolylmethane induce apoptosis in human prostate cancer cells.

Nachshon-Kedmi M, Yannai S, Haj A, Fares FA.

Food Chem Toxicol. 2003 Jun;41(6):745-52.

PMID:
12738179
2.

Translocation of Bax to mitochondria induces apoptotic cell death in indole-3-carbinol (I3C) treated breast cancer cells.

Rahman KM, Aranha O, Glazyrin A, Chinni SR, Sarkar FH.

Oncogene. 2000 Nov 23;19(50):5764-71.

3.

Bcl-2 family-mediated apoptotic effects of 3,3'-diindolylmethane (DIM) in human breast cancer cells.

Hong C, Firestone GL, Bjeldanes LF.

Biochem Pharmacol. 2002 Mar 15;63(6):1085-97.

PMID:
11931841
5.

Induction of apoptosis in MCF-7 cells by indole-3-carbinol is independent of p53 and bax.

Ge X, Fares FA, Yannai S.

Anticancer Res. 1999 Jul-Aug;19(4B):3199-203.

PMID:
10652612
6.

3,3'-diindolylmethane and paclitaxel act synergistically to promote apoptosis in HER2/Neu human breast cancer cells.

McGuire KP, Ngoubilly N, Neavyn M, Lanza-Jacoby S.

J Surg Res. 2006 May 15;132(2):208-13. Epub 2006 Mar 31.

PMID:
16580691
7.
8.

3,3'-Diindolylmethane downregulates pro-survival pathway in hormone independent prostate cancer.

Garikapaty VP, Ashok BT, Tadi K, Mittelman A, Tiwari RK.

Biochem Biophys Res Commun. 2006 Feb 10;340(2):718-25. Epub 2005 Dec 20.

PMID:
16380095
9.

Activation of caspase-8 contributes to 3,3'-Diindolylmethane-induced apoptosis in colon cancer cells.

Kim EJ, Park SY, Shin HK, Kwon DY, Surh YJ, Park JH.

J Nutr. 2007 Jan;137(1):31-6.

10.

3,3'-Diindolylmethane, a cruciferous vegetable derived synthetic anti-proliferative compound in thyroid disease.

Tadi K, Chang Y, Ashok BT, Chen Y, Moscatello A, Schaefer SD, Schantz SP, Policastro AJ, Geliebter J, Tiwari RK.

Biochem Biophys Res Commun. 2005 Nov 25;337(3):1019-25. Epub 2005 Oct 3.

PMID:
16219298
11.

3,3'-diindolylmethane induction of p75NTR-dependent cell death via the p38 mitogen-activated protein kinase pathway in prostate cancer cells.

Khwaja FS, Wynne S, Posey I, Djakiew D.

Cancer Prev Res (Phila). 2009 Jun;2(6):566-71. doi: 10.1158/1940-6207.CAPR-08-0202. Epub 2009 May 26.

12.

Indole-3-carbinol (I3C)-induced apoptosis in nasopharyngeal cancer cells through Fas/FasL and MAPK pathway.

Xu Y, Zhang J, Dong WG.

Med Oncol. 2011 Dec;28(4):1343-8. doi: 10.1007/s12032-010-9619-8. Epub 2010 Jul 14.

PMID:
20628834
14.

Inhibition of proliferation and modulation of estradiol metabolism: novel mechanisms for breast cancer prevention by the phytochemical indole-3-carbinol.

Telang NT, Katdare M, Bradlow HL, Osborne MP, Fishman J.

Proc Soc Exp Biol Med. 1997 Nov;216(2):246-52.

PMID:
9349693
16.

Indole-3-carbinol enhances ultraviolet B-induced apoptosis by sensitizing human melanoma cells.

Kim DS, Jeong YM, Moon SI, Kim SY, Kwon SB, Park ES, Youn SW, Park KC.

Cell Mol Life Sci. 2006 Nov;63(22):2661-8.

PMID:
17086378
17.
18.

Depsipeptide (FR901228) inhibits proliferation and induces apoptosis in primary and metastatic human uveal melanoma cell lines.

Klisovic DD, Katz SE, Effron D, Klisovic MI, Wickham J, Parthun MR, Guimond M, Marcucci G.

Invest Ophthalmol Vis Sci. 2003 Jun;44(6):2390-8.

PMID:
12766035
20.

The dietary phytochemical 3,3'-diindolylmethane induces G2/M arrest and apoptosis in oral squamous cell carcinoma by modulating Akt-NF-κB, MAPK, and p53 signaling.

Weng JR, Bai LY, Chiu CF, Wang YC, Tsai MH.

Chem Biol Interact. 2012 Feb 5;195(3):224-30. doi: 10.1016/j.cbi.2012.01.003. Epub 2012 Jan 24.

PMID:
22290291

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