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Items: 1 to 20 of 303

1.

BeKm-1 is a HERG-specific toxin that shares the structure with ChTx but the mechanism of action with ErgTx1.

Zhang M, Korolkova YV, Liu J, Jiang M, Grishin EV, Tseng GN.

Biophys J. 2003 May;84(5):3022-36.

2.

Mapping the binding site of a human ether-a-go-go-related gene-specific peptide toxin (ErgTx) to the channel's outer vestibule.

Pardo-Lopez L, Zhang M, Liu J, Jiang M, Possani LD, Tseng GN.

J Biol Chem. 2002 May 10;277(19):16403-11. Epub 2002 Feb 25.

3.

New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1.

Korolkova YV, Bocharov EV, Angelo K, Maslennikov IV, Grinenko OV, Lipkin AV, Nosyreva ED, Pluzhnikov KA, Olesen SP, Arseniev AS, Grishin EV.

J Biol Chem. 2002 Nov 8;277(45):43104-9. Epub 2002 Jul 31.

4.

Preferential closed channel blockade of HERG potassium currents by chemically synthesised BeKm-1 scorpion toxin.

Milnes JT, Dempsey CE, Ridley JM, Crociani O, Arcangeli A, Hancox JC, Witchel HJ.

FEBS Lett. 2003 Jul 17;547(1-3):20-6.

5.

An ERG channel inhibitor from the scorpion Buthus eupeus.

Korolkova YV, Kozlov SA, Lipkin AV, Pluzhnikov KA, Hadley JK, Filippov AK, Brown DA, Angelo K, Strøbaek D, Jespersen T, Olesen SP, Jensen BS, Grishin EV.

J Biol Chem. 2001 Mar 30;276(13):9868-76. Epub 2001 Jan 2.

6.

Probing the outer mouth structure of the HERG channel with peptide toxin footprinting and molecular modeling.

Tseng GN, Sonawane KD, Korolkova YV, Zhang M, Liu J, Grishin EV, Guy HR.

Biophys J. 2007 May 15;92(10):3524-40. Epub 2007 Feb 9.

7.

Unique interaction of scorpion toxins with the hERG channel.

Korolkova YV, Tseng GN, Grishin EV.

J Mol Recognit. 2004 May-Jun;17(3):209-17. Review.

PMID:
15137031
8.

Influence of amino-terminal structures on kinetic transitions between several closed and open states in human erg K+ channels.

Gómez-Varela D, de la Peña P, García J, Giráldez T, Barros F.

J Membr Biol. 2002 May 15;187(2):117-33.

PMID:
12029369
9.
10.
11.

Structural and functional role of the extracellular s5-p linker in the HERG potassium channel.

Liu J, Zhang M, Jiang M, Tseng GN.

J Gen Physiol. 2002 Nov;120(5):723-37.

12.

Altered gating of HERG potassium channels by cobalt and lanthanum.

Sanchez-Chapula JA, Sanguinetti MC.

Pflugers Arch. 2000 Jun;440(2):264-74.

PMID:
10898527
13.

Ultrafast inactivation causes inward rectification in a voltage-gated K(+) channel from Caenorhabditis elegans.

Fleischhauer R, Davis MW, Dzhura I, Neely A, Avery L, Joho RH.

J Neurosci. 2000 Jan 15;20(2):511-20.

14.
15.

Saxitoxin is a gating modifier of HERG K+ channels.

Wang J, Salata JJ, Bennett PB.

J Gen Physiol. 2003 Jun;121(6):583-98.

16.

Molecular determinants of voltage-dependent human ether-a-go-go related gene (HERG) K+ channel block.

Sánchez-Chapula JA, Navarro-Polanco RA, Culberson C, Chen J, Sanguinetti MC.

J Biol Chem. 2002 Jun 28;277(26):23587-95. Epub 2002 Apr 17.

17.

Single HERG delayed rectifier K+ channels expressed in Xenopus oocytes.

Zou A, Curran ME, Keating MT, Sanguinetti MC.

Am J Physiol. 1997 Mar;272(3 Pt 2):H1309-14.

PMID:
9087606
18.

Regulation of deactivation by an amino terminal domain in human ether-à-go-go-related gene potassium channels.

Wang J, Trudeau MC, Zappia AM, Robertson GA.

J Gen Physiol. 1998 Nov;112(5):637-47. Erratum in: J Gen Physiol 1999 Feb;113(2):359.

19.

RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies.

Anantharam A, Lewis A, Panaghie G, Gordon E, McCrossan ZA, Lerner DJ, Abbott GW.

J Biol Chem. 2003 Apr 4;278(14):11739-45. Epub 2003 Jan 15.

20.

Open channel block of HERG K(+) channels by vesnarinone.

Kamiya K, Mitcheson JS, Yasui K, Kodama I, Sanguinetti MC.

Mol Pharmacol. 2001 Aug;60(2):244-53.

PMID:
11455010

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