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Items: 1 to 20 of 43

1.

Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1).

Kondo S, Lu Y, Debbas M, Lin AW, Sarosi I, Itie A, Wakeham A, Tuan J, Saris C, Elliott G, Ma W, Benchimol S, Lowe SW, Mak TW, Thukral SK.

Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5431-6.

2.

Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals.

Isono K, Nemoto K, Li Y, Takada Y, Suzuki R, Katsuki M, Nakagawara A, Koseki H.

Mol Cell Biol. 2006 Apr;26(7):2758-71. Erratum in: Mol Cell Biol. 2014 Jul;34(14):2772.

3.

Homeodomain-interacting protein kinase (HIPK)-1 is required for splenic B cell homeostasis and optimal T-independent type 2 humoral response.

Guerra FM, Gommerman JL, Corfe SA, Paige CJ, Rottapel R.

PLoS One. 2012;7(4):e35533. doi: 10.1371/journal.pone.0035533.

4.
6.

HIPK1 drives p53 activation to limit colorectal cancer cell growth.

Rey C, Soubeyran I, Mahouche I, Pedeboscq S, Bessede A, Ichas F, De Giorgi F, Lartigue L.

Cell Cycle. 2013 Jun 15;12(12):1879-91. doi: 10.4161/cc.24927.

7.

SENP1 mediates TNF-induced desumoylation and cytoplasmic translocation of HIPK1 to enhance ASK1-dependent apoptosis.

Li X, Luo Y, Yu L, Lin Y, Luo D, Zhang H, He Y, Kim YO, Kim Y, Tang S, Min W.

Cell Death Differ. 2008 Apr;15(4):739-50. doi: 10.1038/sj.cdd.4402303.

8.

Homeodomain-interacting protein kinase 2 regulates DNA damage response through interacting with heterochromatin protein 1γ.

Akaike Y, Kuwano Y, Nishida K, Kurokawa K, Kajita K, Kano S, Masuda K, Rokutan K.

Oncogene. 2015 Jun;34(26):3463-73. doi: 10.1038/onc.2014.278.

PMID:
25151962
9.

The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase.

Passer BJ, Nancy-Portebois V, Amzallag N, Prieur S, Cans C, Roborel de Climens A, Fiucci G, Bouvard V, Tuynder M, Susini L, Morchoisne S, Crible V, Lespagnol A, Dausset J, Oren M, Amson R, Telerman A.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2284-9.

10.

Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation.

Aikawa Y, Nguyen LA, Isono K, Takakura N, Tagata Y, Schmitz ML, Koseki H, Kitabayashi I.

EMBO J. 2006 Sep 6;25(17):3955-65.

11.

Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiation.

Hattangadi SM, Burke KA, Lodish HF.

Blood. 2010 Jun 10;115(23):4853-61. doi: 10.1182/blood-2009-07-235093.

12.

Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP.

Zhang Q, Yoshimatsu Y, Hildebrand J, Frisch SM, Goodman RH.

Cell. 2003 Oct 17;115(2):177-86.

13.

Mice deficient in poly(C)-binding protein 4 are susceptible to spontaneous tumors through increased expression of ZFP871 that targets p53 for degradation.

Yan W, Scoumanne A, Jung YS, Xu E, Zhang J, Zhang Y, Ren C, Sun P, Chen X.

Genes Dev. 2016 Mar 1;30(5):522-34. doi: 10.1101/gad.271890.115.

14.

Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner.

Hirao A, Cheung A, Duncan G, Girard PM, Elia AJ, Wakeham A, Okada H, Sarkissian T, Wong JA, Sakai T, De Stanchina E, Bristow RG, Suda T, Lowe SW, Jeggo PA, Elledge SJ, Mak TW.

Mol Cell Biol. 2002 Sep;22(18):6521-32.

15.

Enhanced phosphorylation of p53 serine 18 following DNA damage in DNA-dependent protein kinase catalytic subunit-deficient cells.

Araki R, Fukumura R, Fujimori A, Taya Y, Shiloh Y, Kurimasa A, Burma S, Li GC, Chen DJ, Sato K, Hoki Y, Tatsumi K, Abe M.

Cancer Res. 1999 Aug 1;59(15):3543-6.

16.

Regulation of genotoxic stress response by homeodomain-interacting protein kinase 2 through phosphorylation of cyclic AMP response element-binding protein at serine 271.

Sakamoto K, Huang BW, Iwasaki K, Hailemariam K, Ninomiya-Tsuji J, Tsuji Y.

Mol Biol Cell. 2010 Aug 15;21(16):2966-74. doi: 10.1091/mbc.E10-01-0015.

17.

The Tyrosine Kinase c-Abl Promotes Homeodomain-interacting Protein Kinase 2 (HIPK2) Accumulation and Activation in Response to DNA Damage.

Reuven N, Adler J, Porat Z, Polonio-Vallon T, Hofmann TG, Shaul Y.

J Biol Chem. 2015 Jul 3;290(27):16478-88. doi: 10.1074/jbc.M114.628982.

18.

Mdm2 associates with Ras effector NORE1 to induce the degradation of oncoprotein HIPK1.

Lee D, Park SJ, Sung KS, Park J, Lee SB, Park SY, Lee HJ, Ahn JW, Choi SJ, Lee SG, Kim SH, Kim DH, Kim J, Kim Y, Choi CY.

EMBO Rep. 2012 Feb 1;13(2):163-9. doi: 10.1038/embor.2011.235.

19.

DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation.

Raveh T, Droguett G, Horwitz MS, DePinho RA, Kimchi A.

Nat Cell Biol. 2001 Jan;3(1):1-7.

PMID:
11146619
20.
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