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Items: 1 to 20 of 250

1.

Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue.

Laffitte BA, Chao LC, Li J, Walczak R, Hummasti S, Joseph SB, Castrillo A, Wilpitz DC, Mangelsdorf DJ, Collins JL, Saez E, Tontonoz P.

Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5419-24. Epub 2003 Apr 15.

2.

Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha.

Dalen KT, Ulven SM, Bamberg K, Gustafsson JA, Nebb HI.

J Biol Chem. 2003 Nov 28;278(48):48283-91. Epub 2003 Sep 11.

3.

Dissection of the insulin-sensitizing effect of liver X receptor ligands.

Commerford SR, Vargas L, Dorfman SE, Mitro N, Rocheford EC, Mak PA, Li X, Kennedy P, Mullarkey TL, Saez E.

Mol Endocrinol. 2007 Dec;21(12):3002-12. Epub 2007 Aug 23.

PMID:
17717069
4.

Tissue-specific autoregulation of the LXRalpha gene facilitates induction of apoE in mouse adipose tissue.

Ulven SM, Dalen KT, Gustafsson JA, Nebb HI.

J Lipid Res. 2004 Nov;45(11):2052-62. Epub 2004 Aug 1.

5.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling.

Ide T, Shimano H, Yoshikawa T, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Yatoh S, Iizuka Y, Tomita S, Ohashi K, Takahashi A, Sone H, Gotoda T, Osuga J, Ishibashi S, Yamada N.

Mol Endocrinol. 2003 Jul;17(7):1255-67. Epub 2003 May 1.

PMID:
12730332
6.

Type II nuclear hormone receptors, coactivator, and target gene repression in adipose tissue in the acute-phase response.

Lu B, Moser AH, Shigenaga JK, Feingold KR, Grunfeld C.

J Lipid Res. 2006 Oct;47(10):2179-90. Epub 2006 Jul 17.

7.

Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression.

Seo JB, Moon HM, Kim WS, Lee YS, Jeong HW, Yoo EJ, Ham J, Kang H, Park MG, Steffensen KR, Stulnig TM, Gustafsson JA, Park SD, Kim JB.

Mol Cell Biol. 2004 Apr;24(8):3430-44.

8.

Autoregulation of the human liver X receptor alpha promoter.

Laffitte BA, Joseph SB, Walczak R, Pei L, Wilpitz DC, Collins JL, Tontonoz P.

Mol Cell Biol. 2001 Nov;21(22):7558-68.

9.
10.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling.

Yoshikawa T, Ide T, Shimano H, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Yatoh S, Kitamine T, Okazaki H, Tamura Y, Sekiya M, Takahashi A, Hasty AH, Sato R, Sone H, Osuga J, Ishibashi S, Yamada N.

Mol Endocrinol. 2003 Jul;17(7):1240-54. Epub 2003 May 1.

PMID:
12730331
11.

Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis.

Zhou J, Febbraio M, Wada T, Zhai Y, Kuruba R, He J, Lee JH, Khadem S, Ren S, Li S, Silverstein RL, Xie W.

Gastroenterology. 2008 Feb;134(2):556-67. doi: 10.1053/j.gastro.2007.11.037. Epub 2007 Nov 28.

PMID:
18242221
12.

The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions.

Laffitte BA, Joseph SB, Chen M, Castrillo A, Repa J, Wilpitz D, Mangelsdorf D, Tontonoz P.

Mol Cell Biol. 2003 Mar;23(6):2182-91.

13.

Differential effects of pharmacological liver X receptor activation on hepatic and peripheral insulin sensitivity in lean and ob/ob mice.

Grefhorst A, van Dijk TH, Hammer A, van der Sluijs FH, Havinga R, Havekes LM, Romijn JA, Groot PH, Reijngoud DJ, Kuipers F.

Am J Physiol Endocrinol Metab. 2005 Nov;289(5):E829-38. Epub 2005 Jun 7.

14.

The nuclear receptor cofactor, receptor-interacting protein 140, is required for the regulation of hepatic lipid and glucose metabolism by liver X receptor.

Herzog B, Hallberg M, Seth A, Woods A, White R, Parker MG.

Mol Endocrinol. 2007 Nov;21(11):2687-97. Epub 2007 Aug 7.

15.

On the role of liver X receptors in lipid accumulation in adipocytes.

Juvet LK, Andresen SM, Schuster GU, Dalen KT, Tobin KA, Hollung K, Haugen F, Jacinto S, Ulven SM, Bamberg K, Gustafsson JA, Nebb HI.

Mol Endocrinol. 2003 Feb;17(2):172-82.

PMID:
12554745
16.

Evidence for an indirect transcriptional regulation of glucose-6-phosphatase gene expression by liver X receptors.

Grempler R, G√ľnther S, Steffensen KR, Nilsson M, Barthel A, Schmoll D, Walther R.

Biochem Biophys Res Commun. 2005 Dec 16;338(2):981-6. Epub 2005 Oct 17.

PMID:
16256938
17.

Activation of the Liver X Receptor by Agonist TO901317 Improves Hepatic Insulin Resistance via Suppressing Reactive Oxygen Species and JNK Pathway.

Dong Y, Gao G, Fan H, Li S, Li X, Liu W.

PLoS One. 2015 Apr 24;10(4):e0124778. doi: 10.1371/journal.pone.0124778. eCollection 2015.

18.

The nuclear receptor LXR is a glucose sensor.

Mitro N, Mak PA, Vargas L, Godio C, Hampton E, Molteni V, Kreusch A, Saez E.

Nature. 2007 Jan 11;445(7124):219-23. Epub 2006 Dec 24.

PMID:
17187055
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