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Items: 1 to 20 of 113

1.

Cdk5-mediated inhibition of the protective effects of transcription factor MEF2 in neurotoxicity-induced apoptosis.

Gong X, Tang X, Wiedmann M, Wang X, Peng J, Zheng D, Blair LA, Marshall J, Mao Z.

Neuron. 2003 Apr 10;38(1):33-46.

2.

Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2.

Tang X, Wang X, Gong X, Tong M, Park D, Xia Z, Mao Z.

J Neurosci. 2005 May 11;25(19):4823-34.

3.

Implication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium.

Jordà EG, Verdaguer E, Canudas AM, Jiménez A, Garcia de Arriba S, Allgaier C, Pallàs M, Camins A.

Neuroscience. 2005;134(3):1001-11.

PMID:
15979805
4.

Regulation of neuroprotective activity of myocyte-enhancer factor 2 by cAMP-protein kinase A signaling pathway in neuronal survival.

Wang X, Tang X, Li M, Marshall J, Mao Z.

J Biol Chem. 2005 Apr 29;280(17):16705-13. Epub 2005 Feb 25.

5.

Phosphoproteome and transcriptome analysis of the neuronal response to a CDK5 inhibitor.

Gillardon F, Steinlein P, Bürger E, Hildebrandt T, Gerner C.

Proteomics. 2005 Apr;5(5):1299-307.

PMID:
15712243
6.

Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis.

Okamoto S, Li Z, Ju C, Scholzke MN, Mathews E, Cui J, Salvesen GS, Bossy-Wetzel E, Lipton SA.

Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3974-9.

8.

Neuronal activity-dependent cell survival mediated by transcription factor MEF2.

Mao Z, Bonni A, Xia F, Nadal-Vicens M, Greenberg ME.

Science. 1999 Oct 22;286(5440):785-90.

9.

A myocyte enhancer factor 2D (MEF2D) kinase activated during neuronal apoptosis is a novel target inhibited by lithium.

Linseman DA, Cornejo BJ, Le SS, Meintzer MK, Laessig TA, Bouchard RJ, Heidenreich KA.

J Neurochem. 2003 Jun;85(6):1488-99.

10.

p25/Cdk5-mediated retinoblastoma phosphorylation is an early event in neuronal cell death.

Hamdane M, Bretteville A, Sambo AV, Schindowski K, Bégard S, Delacourte A, Bertrand P, Buée L.

J Cell Sci. 2005 Mar 15;118(Pt 6):1291-8. Epub 2005 Mar 1.

11.

Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2.

Smith PD, Mount MP, Shree R, Callaghan S, Slack RS, Anisman H, Vincent I, Wang X, Mao Z, Park DS.

J Neurosci. 2006 Jan 11;26(2):440-7.

12.
13.

Myocyte enhancer factor 2A and 2D undergo phosphorylation and caspase-mediated degradation during apoptosis of rat cerebellar granule neurons.

Li M, Linseman DA, Allen MP, Meintzer MK, Wang X, Laessig T, Wierman ME, Heidenreich KA.

J Neurosci. 2001 Sep 1;21(17):6544-52.

14.

A Cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons.

Zheng YL, Kesavapany S, Gravell M, Hamilton RS, Schubert M, Amin N, Albers W, Grant P, Pant HC.

EMBO J. 2005 Jan 12;24(1):209-20. Epub 2004 Dec 9.

15.

Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling.

Keshvara L, Magdaleno S, Benhayon D, Curran T.

J Neurosci. 2002 Jun 15;22(12):4869-77.

16.

Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death.

O'Hare MJ, Kushwaha N, Zhang Y, Aleyasin H, Callaghan SM, Slack RS, Albert PR, Vincent I, Park DS.

J Neurosci. 2005 Sep 28;25(39):8954-66.

17.

Cyclin-dependent kinase 5 phosphorylates serine 31 of tyrosine hydroxylase and regulates its stability.

Moy LY, Tsai LH.

J Biol Chem. 2004 Dec 24;279(52):54487-93. Epub 2004 Oct 7.

18.

Anti-apoptotic wild-type Alzheimer amyloid precursor protein signaling involves the p38 mitogen-activated protein kinase/MEF2 pathway.

Burton TR, Dibrov A, Kashour T, Amara FM.

Brain Res Mol Brain Res. 2002 Dec;108(1-2):102-20.

PMID:
12480183
19.

Phosphorylation of neuronal survival factor MEF2D by glycogen synthase kinase 3beta in neuronal apoptosis.

Wang X, She H, Mao Z.

J Biol Chem. 2009 Nov 20;284(47):32619-26. doi: 10.1074/jbc.M109.067785. Epub 2009 Sep 29.

20.

Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity.

Fu AK, Fu WY, Ng AK, Chien WW, Ng YP, Wang JH, Ip NY.

Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6728-33. Epub 2004 Apr 19.

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