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Items: 1 to 20 of 86

1.

Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover.

Lund EG, Xie C, Kotti T, Turley SD, Dietschy JM, Russell DW.

J Biol Chem. 2003 Jun 20;278(25):22980-8. Epub 2003 Apr 9.

2.

Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain.

Russell DW, Halford RW, Ramirez DM, Shah R, Kotti T.

Annu Rev Biochem. 2009;78:1017-40. doi: 10.1146/annurev.biochem.78.072407.103859. Review.

3.

Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse.

Meljon A, Wang Y, Griffiths WJ.

Biochem Biophys Res Commun. 2014 Apr 11;446(3):768-74. doi: 10.1016/j.bbrc.2014.01.153. Epub 2014 Jan 31.

4.

Studies on the transcriptional regulation of cholesterol 24-hydroxylase (CYP46A1): marked insensitivity toward different regulatory axes.

Ohyama Y, Meaney S, Heverin M, Ekström L, Brafman A, Shafir M, Andersson U, Olin M, Eggertsen G, Diczfalusy U, Feinstein E, Björkhem I.

J Biol Chem. 2006 Feb 17;281(7):3810-20. Epub 2005 Nov 30.

5.

Disruption of the oxysterol 7alpha-hydroxylase gene in mice.

Li-Hawkins J, Lund EG, Turley SD, Russell DW.

J Biol Chem. 2000 Jun 2;275(22):16536-42.

7.

Brain cholesterol turnover required for geranylgeraniol production and learning in mice.

Kotti TJ, Ramirez DM, Pfeiffer BE, Huber KM, Russell DW.

Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3869-74. Epub 2006 Feb 27.

9.

Marked change in the balance between CYP27A1 and CYP46A1 mediated elimination of cholesterol during differentiation of human neuronal cells.

Milagre I, Olin M, Nunes MJ, Moutinho M, Lövgren-Sandblom A, Gama MJ, Björkhem I, Rodrigues E.

Neurochem Int. 2012 Jan;60(2):192-8. doi: 10.1016/j.neuint.2011.12.003. Epub 2011 Dec 13.

PMID:
22185844
10.

Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in primary cultures of rat hepatocytes.

Pandak WM, Hylemon PB, Ren S, Marques D, Gil G, Redford K, Mallonee D, Vlahcevic ZR.

Hepatology. 2002 Jun;35(6):1400-8.

PMID:
12029625
11.

Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding.

Repa JJ, Lund EG, Horton JD, Leitersdorf E, Russell DW, Dietschy JM, Turley SD.

J Biol Chem. 2000 Dec 15;275(50):39685-92.

12.

Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in the rat.

Ren S, Marques D, Redford K, Hylemon PB, Gil G, Vlahcevic ZR, Pandak WM.

Metabolism. 2003 May;52(5):636-42.

PMID:
12759897
14.

Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA.

Schwarz M, Lund EG, Lathe R, Björkhem I, Russell DW.

J Biol Chem. 1997 Sep 19;272(38):23995-4001.

16.

cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain.

Lund EG, Guileyardo JM, Russell DW.

Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7238-43.

17.
18.

Altered lipid metabolism in apolipoprotein E-deficient mice does not affect cholesterol balance across the liver.

Kuipers F, van Ree JM, Hofker MH, Wolters H, In't Veld G, Havinga R, Vonk RJ, Princen HM, Havekes LM.

Hepatology. 1996 Jul;24(1):241-7.

PMID:
8707269
19.
20.

Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol.

Li-Hawkins J, Lund EG, Bronson AD, Russell DW.

J Biol Chem. 2000 Jun 2;275(22):16543-9.

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