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Items: 1 to 20 of 94

1.

Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption.

Ke HZ, Qi H, Weidema AF, Zhang Q, Panupinthu N, Crawford DT, Grasser WA, Paralkar VM, Li M, Audoly LP, Gabel CA, Jee WS, Dixon SJ, Sims SM, Thompson DD.

Mol Endocrinol. 2003 Jul;17(7):1356-67. Epub 2003 Apr 3.

PMID:
12677010
2.
3.

Blockade of the pore-forming P2X7 receptor inhibits formation of multinucleated human osteoclasts in vitro.

Gartland A, Buckley KA, Bowler WB, Gallagher JA.

Calcif Tissue Int. 2003 Oct;73(4):361-9. Epub 2003 Jul 24.

PMID:
12874700
4.

Disruption of the insulin-like growth factor-1 gene in osteocytes impairs developmental bone growth in mice.

Sheng MH, Zhou XD, Bonewald LF, Baylink DJ, Lau KH.

Bone. 2013 Jan;52(1):133-44. doi: 10.1016/j.bone.2012.09.027. Epub 2012 Sep 29.

PMID:
23032105
5.

The P2Y13 receptor regulates phosphate metabolism and FGF-23 secretion with effects on skeletal development.

Wang N, Robaye B, Gossiel F, Boeynaems JM, Gartland A.

FASEB J. 2014 May;28(5):2249-59. doi: 10.1096/fj.13-243626. Epub 2014 Jan 31.

6.

Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development.

Okamoto M, Murai J, Yoshikawa H, Tsumaki N.

J Bone Miner Res. 2006 Jul;21(7):1022-33.

7.

Disordered osteoclast formation and function in a CD38 (ADP-ribosyl cyclase)-deficient mouse establishes an essential role for CD38 in bone resorption.

Sun L, Iqbal J, Dolgilevich S, Yuen T, Wu XB, Moonga BS, Adebanjo OA, Bevis PJ, Lund F, Huang CL, Blair HC, Abe E, Zaidi M.

FASEB J. 2003 Mar;17(3):369-75.

PMID:
12631576
8.

IL-1 plays an important role in the bone metabolism under physiological conditions.

Lee YM, Fujikado N, Manaka H, Yasuda H, Iwakura Y.

Int Immunol. 2010 Oct;22(10):805-16. doi: 10.1093/intimm/dxq431. Epub 2010 Aug 2.

PMID:
20679512
9.

Osteopenia and impaired fracture healing in aged EP4 receptor knockout mice.

Li M, Healy DR, Li Y, Simmons HA, Crawford DT, Ke HZ, Pan LC, Brown TA, Thompson DD.

Bone. 2005 Jul;37(1):46-54.

PMID:
15869929
10.

Proteinase-activated receptor-2 is required for normal osteoblast and osteoclast differentiation during skeletal growth and repair.

Georgy SR, Pagel CN, Ghasem-Zadeh A, Zebaze RM, Pike RN, Sims NA, Mackie EJ.

Bone. 2012 Mar;50(3):704-12. doi: 10.1016/j.bone.2011.11.023. Epub 2011 Dec 7.

PMID:
22173052
11.

P2X7 nucleotide receptors mediate blebbing in osteoblasts through a pathway involving lysophosphatidic acid.

Panupinthu N, Zhao L, Possmayer F, Ke HZ, Sims SM, Dixon SJ.

J Biol Chem. 2007 Feb 2;282(5):3403-12. Epub 2006 Nov 29.

12.

Multinucleated osteoclast formation in vivo and in vitro by P2X7 receptor-deficient mice.

Gartland A, Buckley KA, Hipskind RA, Perry MJ, Tobias JH, Buell G, Chessell I, Bowler WB, Gallagher JA.

Crit Rev Eukaryot Gene Expr. 2003;13(2-4):243-53.

PMID:
14696971
13.

Expression of either NF-kappaB p50 or p52 in osteoclast precursors is required for IL-1-induced bone resorption.

Xing L, Carlson L, Story B, Tai Z, Keng P, Siebenlist U, Boyce BF.

J Bone Miner Res. 2003 Feb;18(2):260-9.

14.

Glycoprotein130 (Gp130)/interleukin-6 (IL-6) signalling in osteoclasts promotes bone formation in periosteal and trabecular bone.

Johnson RW, McGregor NE, Brennan HJ, Crimeen-Irwin B, Poulton IJ, Martin TJ, Sims NA.

Bone. 2015 Dec;81:343-51. doi: 10.1016/j.bone.2015.08.005. Epub 2015 Aug 7.

PMID:
26255596
15.

Inducible nitric oxide synthase mediates bone development and P. gingivalis-induced alveolar bone loss.

Gyurko R, Shoji H, Battaglino RA, Boustany G, Gibson FC 3rd, Genco CA, Stashenko P, Van Dyke TE.

Bone. 2005 Mar;36(3):472-9.

PMID:
15777672
16.

Severe developmental bone phenotype in ClC-7 deficient mice.

Neutzsky-Wulff AV, Sims NA, Supanchart C, Kornak U, Felsenberg D, Poulton IJ, Martin TJ, Karsdal MA, Henriksen K.

Dev Biol. 2010 Aug 15;344(2):1001-10. doi: 10.1016/j.ydbio.2010.06.018. Epub 2010 Jun 22.

17.

A comparison of osteoclast-rich and osteoclast-poor osteopetrosis in adult mice sheds light on the role of the osteoclast in coupling bone resorption and bone formation.

Thudium CS, Moscatelli I, Flores C, Thomsen JS, BrĂ¼el A, Gudmann NS, Hauge EM, Karsdal MA, Richter J, Henriksen K.

Calcif Tissue Int. 2014 Jul;95(1):83-93. doi: 10.1007/s00223-014-9865-4. Epub 2014 May 18.

PMID:
24838599
18.

The P2X7 nucleotide receptor mediates skeletal mechanotransduction.

Li J, Liu D, Ke HZ, Duncan RL, Turner CH.

J Biol Chem. 2005 Dec 30;280(52):42952-9. Epub 2005 Nov 3.

19.

Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function.

Udagawa N, Takahashi N, Yasuda H, Mizuno A, Itoh K, Ueno Y, Shinki T, Gillespie MT, Martin TJ, Higashio K, Suda T.

Endocrinology. 2000 Sep;141(9):3478-84.

PMID:
10965921
20.

Bone phenotypes of P2 receptor knockout mice.

Orriss I, Syberg S, Wang N, Robaye B, Gartland A, Jorgensen N, Arnett T, Boeynaems JM.

Front Biosci (Schol Ed). 2011 Jun 1;3:1038-46.

PMID:
21622253

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