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L-SIGN (CD 209L) is a liver-specific capture receptor for hepatitis C virus.

Gardner JP, Durso RJ, Arrigale RR, Donovan GP, Maddon PJ, Dragic T, Olson WC.

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4498-503. Epub 2003 Apr 3.


L-SIGN (CD209L) isoforms differently mediate trans-infection of hepatoma cells by hepatitis C virus pseudoparticles.

Falkowska E, Durso RJ, Gardner JP, Cormier EG, Arrigale RA, Ogawa RN, Donovan GP, Maddon PJ, Olson WC, Dragic T.

J Gen Virol. 2006 Sep;87(Pt 9):2571-6.


Hepatitis C virus targets DC-SIGN and L-SIGN to escape lysosomal degradation.

Ludwig IS, Lekkerkerker AN, Depla E, Bosman F, Musters RJ, Depraetere S, van Kooyk Y, Geijtenbeek TB.

J Virol. 2004 Aug;78(15):8322-32.


A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection.

Bashirova AA, Geijtenbeek TB, van Duijnhoven GC, van Vliet SJ, Eilering JB, Martin MP, Wu L, Martin TD, Viebig N, Knolle PA, KewalRamani VN, van Kooyk Y, Carrington M.

J Exp Med. 2001 Mar 19;193(6):671-8.


DC-SIGN: binding receptors for hepatitis C virus.

Wang QC, Feng ZH, Nie QH, Zhou YX.

Chin Med J (Engl). 2004 Sep;117(9):1395-400. Review.


L-SIGN (CD209L) and DC-SIGN (CD209) mediate transinfection of liver cells by hepatitis C virus.

Cormier EG, Durso RJ, Tsamis F, Boussemart L, Manix C, Olson WC, Gardner JP, Dragic T.

Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14067-72. Epub 2004 Sep 15.


Analysis of the interaction of Ebola virus glycoprotein with DC-SIGN (dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin) and its homologue DC-SIGNR.

Marzi A, Möller P, Hanna SL, Harrer T, Eisemann J, Steinkasserer A, Becker S, Baribaud F, Pöhlmann S.

J Infect Dis. 2007 Nov 15;196 Suppl 2:S237-46.


Role of N-linked glycans in the interactions of recombinant HCV envelope glycoproteins with cellular receptors.

Chen PC, Chuang PK, Chen CH, Chan YT, Chen JR, Lin SW, Ma C, Hsu TL, Wong CH.

ACS Chem Biol. 2014 Jul 18;9(7):1437-43. doi: 10.1021/cb500121c. Epub 2014 May 15.


Molecular basis of the differences in binding properties of the highly related C-type lectins DC-SIGN and L-SIGN to Lewis X trisaccharide and Schistosoma mansoni egg antigens.

Van Liempt E, Imberty A, Bank CM, Van Vliet SJ, Van Kooyk Y, Geijtenbeek TB, Van Die I.

J Biol Chem. 2004 Aug 6;279(32):33161-7. Epub 2004 Jun 7.


Structural requirements for multimerization of the pathogen receptor dendritic cell-specific ICAM3-grabbing non-integrin (CD209) on the cell surface.

Serrano-Gómez D, Sierra-Filardi E, Martínez-Nuñez RT, Caparrós E, Delgado R, Muñoz-Fernández MA, Abad MA, Jimenez-Barbero J, Leal M, Corbí AL.

J Biol Chem. 2008 Feb 15;283(7):3889-903. Epub 2007 Dec 11.


The C-type lectin L-SIGN differentially recognizes glycan antigens on egg glycosphingolipids and soluble egg glycoproteins from Schistosoma mansoni.

Meyer S, Tefsen B, Imberty A, Geyer R, van Die I.

Glycobiology. 2007 Oct;17(10):1104-19. Epub 2007 Jul 9.


C-type lectins L-SIGN and DC-SIGN capture and transmit infectious hepatitis C virus pseudotype particles.

Lozach PY, Amara A, Bartosch B, Virelizier JL, Arenzana-Seisdedos F, Cosset FL, Altmeyer R.

J Biol Chem. 2004 Jul 30;279(31):32035-45. Epub 2004 May 27.


Role of DC-SIGN in the activation of dendritic cells by HPV-16 L1 virus-like particle vaccine.

García-Piñeres AJ, Hildesheim A, Trivett M, Williams M, Wu L, Kewalramani VN, Pinto LA.

Eur J Immunol. 2006 Feb;36(2):437-45.


Uptake and presentation of hepatitis C virus-like particles by human dendritic cells.

Barth H, Ulsenheimer A, Pape GR, Diepolder HM, Hoffmann M, Neumann-Haefelin C, Thimme R, Henneke P, Klein R, Paranhos-Baccalà G, Depla E, Liang TJ, Blum HE, Baumert TF.

Blood. 2005 May 1;105(9):3605-14. Epub 2005 Jan 18.


DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2.

Lozach PY, Lortat-Jacob H, de Lacroix de Lavalette A, Staropoli I, Foung S, Amara A, Houles C, Fieschi F, Schwartz O, Virelizier JL, Arenzana-Seisdedos F, Altmeyer R.

J Biol Chem. 2003 May 30;278(22):20358-66. Epub 2003 Feb 27.


Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4+ T lymphocytes.

van Montfort T, Nabatov AA, Geijtenbeek TB, Pollakis G, Paxton WA.

J Immunol. 2007 Mar 1;178(5):3177-85.


Proteomic analysis of DC-SIGN on dendritic cells detects tetramers required for ligand binding but no association with CD4.

Bernhard OK, Lai J, Wilkinson J, Sheil MM, Cunningham AL.

J Biol Chem. 2004 Dec 10;279(50):51828-35. Epub 2004 Sep 22.


Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR.

Feinberg H, Mitchell DA, Drickamer K, Weis WI.

Science. 2001 Dec 7;294(5549):2163-6.


Isolation and characterization of the human DC-SIGN and DC-SIGNR promoters.

Liu H, Yu W, Liou LY, Rice AP.

Gene. 2003 Aug 14;313:149-59.


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