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Items: 1 to 20 of 126

1.

Protein kinase C-theta (PKCtheta): it's all about location, location, location.

Altman A, Villalba M.

Immunol Rev. 2003 Apr;192:53-63. Review.

PMID:
12670395
2.

Protein kinase C-theta (PKC theta): a key enzyme in T cell life and death.

Altman A, Villalba M.

J Biochem. 2002 Dec;132(6):841-6. Review.

3.

Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.

Altman A, Kaminski S, Busuttil V, Droin N, Hu J, Tadevosyan Y, Hipskind RA, Villalba M.

Eur J Immunol. 2004 Jul;34(7):2001-11.

4.

Characterization of TCR-induced phosphorylation of PKCtheta in primary murine lymphocytes.

Thebault S, Ochoa-Garay J.

Mol Immunol. 2004 Feb;40(13):931-42.

PMID:
14725789
5.

Filamin A is required for T cell activation mediated by protein kinase C-theta.

Hayashi K, Altman A.

J Immunol. 2006 Aug 1;177(3):1721-8.

6.

Protein kinase C-theta (PKCtheta), a potential drug target for therapeutic intervention with human T cell leukemias.

Villalba M, Altman A.

Curr Cancer Drug Targets. 2002 Jun;2(2):125-37. Review.

PMID:
12188914
7.

Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C.

Villalba M, Bi K, Hu J, Altman Y, Bushway P, Reits E, Neefjes J, Baier G, Abraham RT, Altman A.

J Cell Biol. 2002 Apr 15;157(2):253-63. Epub 2002 Apr 15.

8.

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

Villalba M, Coudronniere N, Deckert M, Teixeiro E, Mas P, Altman A.

Immunity. 2000 Feb;12(2):151-60.

9.

Membrane lipid microdomains and the role of PKCtheta in T cell activation.

Bi K, Altman A.

Semin Immunol. 2001 Apr;13(2):139-46. Review.

PMID:
11308297
10.

SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway.

Li Y, Hu J, Vita R, Sun B, Tabata H, Altman A.

EMBO J. 2004 Mar 10;23(5):1112-22. Epub 2004 Feb 26.

11.

Protein kinase C theta plays a fundamental role in different types of chronic colitis.

Nagahama K, Ogawa A, Shirane K, Shimomura Y, Sugimoto K, Mizoguchi A.

Gastroenterology. 2008 Feb;134(2):459-69. Epub 2007 Nov 5.

PMID:
18155708
12.

Membrane raft association of CD47 is necessary for actin polymerization and protein kinase C theta translocation in its synergistic activation of T cells.

Rebres RA, Green JM, Reinhold MI, Ticchioni M, Brown EJ.

J Biol Chem. 2001 Mar 9;276(10):7672-80. Epub 2000 Dec 12.

13.

Mitogenic signals through CD28 activate the protein kinase Ctheta-NF-kappaB pathway in primary peripheral T cells.

Dennehy KM, Kerstan A, Bischof A, Park JH, Na SY, Hünig T.

Int Immunol. 2003 May;15(5):655-63.

PMID:
12697665
14.

New perspectives on PKCtheta, a member of the novel subfamily of protein kinase C.

Meller N, Altman A, Isakov N.

Stem Cells. 1998;16(3):178-92. Review.

15.

Perspectives on PKCtheta in T cell activation.

Sedwick CE, Altman A.

Mol Immunol. 2004 Jul;41(6-7):675-86. Review.

PMID:
15220003
16.

Dietary docosahexaenoic acid suppresses T cell protein kinase C theta lipid raft recruitment and IL-2 production.

Fan YY, Ly LH, Barhoumi R, McMurray DN, Chapkin RS.

J Immunol. 2004 Nov 15;173(10):6151-60.

17.

Protein kinase C theta cooperates with Vav1 to induce JNK activity in T-cells.

Möller A, Dienz O, Hehner SP, Dröge W, Schmitz ML.

J Biol Chem. 2001 Jun 8;276(23):20022-8. Epub 2001 Mar 23.

18.

Protein kinase Ctheta focusing at the cSMAC is a consequence rather than cause of TCR signaling and is dependent on the MEK/ERK pathway.

Praveen K, Zheng Y, Rivas F, Gajewski TF.

J Immunol. 2009 May 15;182(10):6022-30. doi: 10.4049/jimmunol.0800897.

19.
20.

Protein kinase Ctheta: a new essential superstar on the T-cell stage.

Altman A, Isakov N, Baier G.

Immunol Today. 2000 Nov;21(11):567-73. Review.

PMID:
11094261

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