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Items: 1 to 20 of 129

1.

The structural basis of a conserved P2 threonine in canonical serine proteinase inhibitors.

Brauer AB, Nievo M, McBride JD, Leatherbarrow RJ.

J Biomol Struct Dyn. 2003 Apr;20(5):645-56.

PMID:
12643767
2.
3.

The absolute structural requirement for a proline in the P3'-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold.

Daly NL, Chen YK, Foley FM, Bansal PS, Bharathi R, Clark RJ, Sommerhoff CP, Craik DJ.

J Biol Chem. 2006 Aug 18;281(33):23668-75. Epub 2006 Jun 9.

4.

The conserved P1' Ser of Bowman-Birk-type proteinase inhibitors is not essential for the integrity of the reactive site loop.

Brauer AB, Leatherbarrow RJ.

Biochem Biophys Res Commun. 2003 Aug 22;308(2):300-5.

PMID:
12901868
5.
6.

A conserved cis peptide bond is necessary for the activity of Bowman-Birk inhibitor protein.

Brauer AB, Domingo GJ, Cooke RM, Matthews SJ, Leatherbarrow RJ.

Biochemistry. 2002 Aug 27;41(34):10608-15.

PMID:
12186545
7.
8.

Synthetic peptide mimics of the Bowman-Birk inhibitor protein.

McBride JD, Leatherbarrow RJ.

Curr Med Chem. 2001 Jul;8(8):909-17. Review.

PMID:
11375759
9.

Homologous proteins with different folds: the three-dimensional structures of domains 1 and 6 of the multiple Kazal-type inhibitor LEKTI.

Lauber T, Schulz A, Schweimer K, Adermann K, Marx UC.

J Mol Biol. 2003 Apr 18;328(1):205-19.

PMID:
12684009
10.

Biological significance of polymorphism in legume protease inhibitors from the Bowman-Birk family.

Clementea A, Domoney C.

Curr Protein Pept Sci. 2006 Jun;7(3):201-16. Review.

PMID:
16787260
11.

Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution.

Tsunemi M, Matsuura Y, Sakakibara S, Katsube Y.

Biochemistry. 1996 Sep 10;35(36):11570-6.

PMID:
8794736
12.

Selective removal of individual disulfide bonds within a potato type II serine proteinase inhibitor from Nicotiana alata reveals differential stabilization of the reactive-site loop.

Schirra HJ, Guarino RF, Anderson MA, Craik DJ.

J Mol Biol. 2010 Jan 22;395(3):609-26. doi: 10.1016/j.jmb.2009.11.031. Epub 2009 Nov 17.

PMID:
19925809
13.

Identification of chymotrypsin inhibitors from a second-generation template assisted combinatorial peptide library.

McBride JD, Freeman HN, Leatherbarrow RJ.

J Pept Sci. 2000 Sep;6(9):446-52.

PMID:
11016881
14.

Selection of chymotrypsin inhibitors from a conformationally-constrained combinatorial peptide library.

McBride JD, Freeman N, Domingo GJ, Leatherbarrow RJ.

J Mol Biol. 1996 Jun 21;259(4):819-27.

PMID:
8683585
15.

Extended intermolecular interactions in a serine protease-canonical inhibitor complex account for strong and highly specific inhibition.

Fodor K, Harmat V, Hetényi C, Kardos J, Antal J, Perczel A, Patthy A, Katona G, Gráf L.

J Mol Biol. 2005 Jul 1;350(1):156-69.

PMID:
15922357
16.

Probing intermolecular backbone H-bonding in serine proteinase-protein inhibitor complexes.

Lu W, Randal M, Kossiakoff A, Kent SB.

Chem Biol. 1999 Jul;6(7):419-27.

17.

Synthesis of a mixture of cyclic peptides based on the Bowman-Birk reactive site loop to screen for serine protease inhibitors.

Domingo GJ, Leatherbarrow RJ, Freeman N, Patel S, Weir M.

Int J Pept Protein Res. 1995 Jul;46(1):79-87.

PMID:
7558601
18.

Design of serine proteinase inhibitors by combinatorial chemistry using trypsin inhibitor SFTI-1 as a starting structure.

Zabłotna E, Jaśkiewicz A, Łegowska A, Miecznikowska H, Lesner A, Rolka K.

J Pept Sci. 2007 Nov;13(11):749-55.

PMID:
17828796
19.

Thrombin receptor-activating peptides (TRAPs): investigation of bioactive conformations via structure-activity, spectroscopic, and computational studies.

Ceruso MA, McComsey DF, Leo GC, Andrade-Gordon P, Addo MF, Scarborough RM, Oksenberg D, Maryanoff BE.

Bioorg Med Chem. 1999 Nov;7(11):2353-71.

PMID:
10632045
20.

Thermodynamic criterion for the conformation of P1 residues of substrates and of inhibitors in complexes with serine proteinases.

Qasim MA, Lu SM, Ding J, Bateman KS, James MN, Anderson S, Song J, Markley JL, Ganz PJ, Saunders CW, Laskowski M Jr.

Biochemistry. 1999 Jun 1;38(22):7142-50.

PMID:
10353824

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