Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 61

1.

Gene silencing--a new theory of aging.

Burzynski SR.

Med Hypotheses. 2003 Apr;60(4):578-83.

PMID:
12615527
2.

Aging: gene silencing or gene activation?

Burzynski SR.

Med Hypotheses. 2005;64(1):201-8.

PMID:
15533642
4.

DNA methyltransferase 1 knock down induces gene expression by a mechanism independent of DNA methylation and histone deacetylation.

Milutinovic S, Brown SE, Zhuang Q, Szyf M.

J Biol Chem. 2004 Jul 2;279(27):27915-27. Epub 2004 Apr 15.

5.

Reversal of gene silencing as a therapeutic target for cancer--roles for DNA methylation and its interdigitation with chromatin.

Baylin SB.

Novartis Found Symp. 2004;259:226-33; discussion 234-7, 285-8. Review.

PMID:
15171257
6.

Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines.

Ou JN, Torrisani J, Unterberger A, Provençal N, Shikimi K, Karimi M, Ekström TJ, Szyf M.

Biochem Pharmacol. 2007 May 1;73(9):1297-307. Epub 2007 Jan 5.

PMID:
17276411
7.
8.

Inhibitors of DNA methylation and histone deacetylation activate cytomegalovirus promoter-controlled reporter gene expression in human glioblastoma cell line U87.

Grassi G, Maccaroni P, Meyer R, Kaiser H, D'Ambrosio E, Pascale E, Grassi M, Kuhn A, Di Nardo P, Kandolf R, Küpper JH.

Carcinogenesis. 2003 Oct;24(10):1625-35. Epub 2003 Jul 17.

9.

Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation.

Pruitt K, Zinn RL, Ohm JE, McGarvey KM, Kang SH, Watkins DN, Herman JG, Baylin SB.

PLoS Genet. 2006 Mar;2(3):e40. Epub 2006 Mar 31.

10.

Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation.

Kondo Y, Shen L, Yan PS, Huang TH, Issa JP.

Proc Natl Acad Sci U S A. 2004 May 11;101(19):7398-403. Epub 2004 May 3.

11.

Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation.

Jacinto FV, Ballestar E, Esteller M.

Oncogene. 2009 Nov 26;28(47):4212-24. doi: 10.1038/onc.2009.267. Epub 2009 Sep 7.

PMID:
19734945
12.
13.

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation.

Kondo Y, Shen L, Cheng AS, Ahmed S, Boumber Y, Charo C, Yamochi T, Urano T, Furukawa K, Kwabi-Addo B, Gold DL, Sekido Y, Huang TH, Issa JP.

Nat Genet. 2008 Jun;40(6):741-50. doi: 10.1038/ng.159. Epub 2008 May 18.

PMID:
18488029
14.

Epigenetic interplay between histone modifications and DNA methylation in gene silencing.

Vaissière T, Sawan C, Herceg Z.

Mutat Res. 2008 Jul-Aug;659(1-2):40-8. doi: 10.1016/j.mrrev.2008.02.004. Epub 2008 Feb 29. Review.

PMID:
18407786
15.

Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer.

Wang LG, Beklemisheva A, Liu XM, Ferrari AC, Feng J, Chiao JW.

Mol Carcinog. 2007 Jan;46(1):24-31.

PMID:
16921492
16.

Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter.

Strunnikova M, Schagdarsurengin U, Kehlen A, Garbe JC, Stampfer MR, Dammann R.

Mol Cell Biol. 2005 May;25(10):3923-33.

17.

Analysis of specific lysine histone H3 and H4 acetylation and methylation status in clones of cells with a gene silenced by nickel exposure.

Yan Y, Kluz T, Zhang P, Chen HB, Costa M.

Toxicol Appl Pharmacol. 2003 Aug 1;190(3):272-7.

PMID:
12902198
18.

Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter.

Wu LP, Wang X, Li L, Zhao Y, Lu S, Yu Y, Zhou W, Liu X, Yang J, Zheng Z, Zhang H, Feng J, Yang Y, Wang H, Zhu WG.

Mol Cell Biol. 2008 May;28(10):3219-35. doi: 10.1128/MCB.01516-07. Epub 2008 Mar 10.

19.

Halogenated thymidine analogues restore the expression of silenced genes without demethylation.

Fan J, Kodama E, Koh Y, Nakao M, Matsuoka M.

Cancer Res. 2005 Aug 1;65(15):6927-33.

20.

Dominant-negative histone H3 lysine 27 mutant derepresses silenced tumor suppressor genes and reverses the drug-resistant phenotype in cancer cells.

Abbosh PH, Montgomery JS, Starkey JA, Novotny M, Zuhowski EG, Egorin MJ, Moseman AP, Golas A, Brannon KM, Balch C, Huang TH, Nephew KP.

Cancer Res. 2006 Jun 1;66(11):5582-91.

Items per page

Supplemental Content

Write to the Help Desk