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12589052,17299140,12374793,12545162,15684397,11438700,15143069,15480895,11598109,12029621,15069087,12538652,12853969,12760970,11840268,12560323,15811853,11744690,16183734,12947087,15743758,14500648,10480932,11278290,12829618,11716483,15132952,10748100,14576166,11401854,15708859,11477069,15133024,10801443,15922743,11453551,11907271,18758450,10850453,17096210,15203191,24096742,11134003,15728539,10571779,12734193,10527909,16157589,10504490,35184673,12206715,15075243,11448947,15300592,15067346,12646044,10413589,15107418,12219008,11376873,11560950,11516623,10874022,22641218,18299321,11737269,14722617,15208664,15153551,12130649,12384504,15078890,15632190,20978232,11290520,10627526,10514514,10064600,11564875,12151339,11477097,12876289,10846060,11948180,15567067,14678985,15187003,10871205,11181412,14718543,12556533,12081893,15716330,12821934,11886529,12097262,12456654,33148869,9278437,15277532,15294900,11964407,25451097,10570156,11278814,25849436,12601065,16914898,11745435,12893825,14561830,15247230,12728250,15273249,12019309,11904165,11208641,12110587,12637505,20599490,11679966,11857403,15609398,12377770,11585905,14634666,10636915,12118074,29705706,9430721,11358848,11960349,12839928,10757800,15980430,12589053,15447977,10085140,14595120,16246848,9786930,15201140,12933797,10862759,16624629,11795877,10585406,16051607,12270924,19556242,11848492,11590169,10995749,15905080,11799106,9435505,11773065,10085121,12393612,12459458,15068691,14970210,16407830,12712406,12376363,10363999,17173073,15647284,14521923,12118366,15579469,11104763,14514699,14512875,29893818,12947156,12419465,12234288,11937560,11762872,14988821,9162092,15647278,10644681,17172861,10835427,11495898,20551513,8663074,10661401,11309380,15184388,11712667,24072697,28674186,14630909,11741826,12670941,10580747,14993265,14633627,12639893,21931165,15546505,15831522,10878008,11053476,10625669,12381518,19352540,13679851,14709549,12894225,14672918,29661023,15761973,20959347,29229918,15213232,12815042,15737997,11668037,12082091,14642090,12200968,16908447,12121971,11707697,15274293,12370186,28445989,10757786,10748131,15657037,19201899,12480183,14517210,16000313,23546880,12679868,24728340,16924420,14688282,12058028,14510976,16831683,15964803,12376555,12783777,12054652,14691160,20392803,9442057,16781040,24482239,11888934,12021267,15001534,10838074,11980910,23242502,16125722,12473108,9735409,11865055,16120811,10196228,11842088,9374491,17513491,21303922,22496417,11278251,15797859,10842172,12859960,10997691,11912247,26888387,10224067,10801843,19544470,14657019,18922473,23391818,12876385,21030067,11593045,15921779,8663331,14600158,16139919,11718727,12208955,19074436,11855979,14688258,28628118,22525462,19875456,29504713,10925306,12226090,9335507,15004007,32594651,20511342,10542264,33799767,11046029,16598785,27048361,25035980,15911626,14617800,20730577,11309387,14741692,19224920,12600835,18586026,9038352,16849316,32777238,23760366,18922143,11513480,18413810,28821620,31545406,15743788,12889600,11397816,15946939,15368444,12429732,19047046,15192088,16251192,14592977,9712726,10713669,14732719,15240683,10986282,10075017,11536048,11312036,26573508,12888549,12139758,11287182,34455616,10075149,12473651,17932218,12127716,22696064,16236272,20023695,15767673,12407115,12878171,15084590,16360132,12624112,20980434,23468994,22751114,17276978,27322208,16807361,12649123,11511516,11683954,29124661,20659902,10224135,11927620,8638164,12733703,26205654,16845370,15448476,28209993,22522454,15128733,10819748,15894542,12270637,11322385,15590691,21371434,29145973,10549623,23331010,11847191,12239215,25483191,11884518,21980489,12244047,19115422,31077183,10617642,22337877,11978861,18762808,12189134,33111211,26858265,18974393,16257974,10048449,34560609,32820312,31419505,26491199,14556849,24958208,25028512,10899902,16930512,12814935,11880276,11790788,35460836,15917296,11599127,15661223,17828308,19427893,15778378,14705642,14742254,35637967,14676202,28224764,17382930,18562633,30523245,33327477,30953345,22351764,32096184,9722602,21371426,29423686,28433746,17327237,26658711,30250565,14765985,19995910,18189266,18156442,32460580,12151385,10644746,12089430,15218018,30161000,29777109,12435397,24863656,12719431,17631503,27026702,30081740,32034714,10702308,12665513,16709837,29171240,12464953,17079228,32543140,12860278,28739872,30111748,10525544,26919443,21625229,28732737,12643470,12811827,34537073,11836244,12771931,12972603,32343849,22529104,16778458,10903068,30626936,14514014,31387937,24466111,35442672,22649101,17088559,36583708,17332363,8533096,27426734,15514103,31028803,15383266,23926672,16690609,22656308,19961337,11099781,9210400,23664135,29414666,19455458,14612410,24343358,15055198,22805309,29467907,17098745,12133618,18087998,23565059,12747808,22989755,26823762,14670949,23688753,30720101,12048196,16141544,27679858,12185267,11305107,17680340,17406030,18332137,12464436,20339548,15260968,27402796,27161454,36870282,19631696,7753711,12086621,36008477,14642781,12711537,12037130,33068010,30530226,31461795,14981536,19482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Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3.

Edlund S, Bu S, Schuster N, Aspenström P, Heuchel R, Heldin NE, ten Dijke P, Heldin CH, Landström M. Edlund S, et al. Mol Biol Cell. 2003 Feb;14(2):529-44. doi: 10.1091/mbc.02-03-0037. Mol Biol Cell. 2003. PMID: 12589052 Free PMC article.

TGF-beta-activated kinase 1 and TAK1-binding protein 1 cooperate to mediate TGF-beta1-induced MKK3-p38 MAPK activation and stimulation of type I collagen.

Kim SI, Kwak JH, Zachariah M, He Y, Wang L, Choi ME. Kim SI, et al. Am J Physiol Renal Physiol. 2007 May;292(5):F1471-8. doi: 10.1152/ajprenal.00485.2006. Epub 2007 Feb 13. Am J Physiol Renal Physiol. 2007. PMID: 17299140 Free article.

Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for activation of p38alpha and p38delta MAPK isoforms by TGF-beta 1 in murine mesangial cells.

Wang L, Ma R, Flavell RA, Choi ME. Wang L, et al. J Biol Chem. 2002 Dec 6;277(49):47257-62. doi: 10.1074/jbc.M208573200. Epub 2002 Oct 8. J Biol Chem. 2002. PMID: 12374793 Free article.

Transient activation of NF-kappaB through a TAK1/IKK kinase pathway by TGF-beta1 inhibits AP-1/SMAD signaling and apoptosis: implications in liver tumor formation.

Arsura M, Panta GR, Bilyeu JD, Cavin LG, Sovak MA, Oliver AA, Factor V, Heuchel R, Mercurio F, Thorgeirsson SS, Sonenshein GE. Arsura M, et al. Oncogene. 2003 Jan 23;22(3):412-25. doi: 10.1038/sj.onc.1206132. Oncogene. 2003. PMID: 12545162

Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis.

Edlund S, Lee SY, Grimsby S, Zhang S, Aspenström P, Heldin CH, Landström M. Edlund S, et al. Mol Cell Biol. 2005 Feb;25(4):1475-88. doi: 10.1128/MCB.25.4.1475-1488.2005. Mol Cell Biol. 2005. PMID: 15684397 Free PMC article.

Activation of NF-kappa B by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK-IKK alpha /beta-I kappa B alpha and MKK3/6-p38 MAP kinase signaling pathways in epithelial cells.

Shuto T, Xu H, Wang B, Han J, Kai H, Gu XX, Murphy TF, Lim DJ, Li JD. Shuto T, et al. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8774-9. doi: 10.1073/pnas.151236098. Epub 2001 Jul 3. Proc Natl Acad Sci U S A. 2001. PMID: 11438700 Free PMC article.

Transforming growth factor-beta1 stimulates vascular endothelial growth factor 164 via mitogen-activated protein kinase kinase 3-p38alpha and p38delta mitogen-activated protein kinase-dependent pathway in murine mesangial cells.

Wang L, Kwak JH, Kim SI, He Y, Choi ME. Wang L, et al. J Biol Chem. 2004 Aug 6;279(32):33213-9. doi: 10.1074/jbc.M403758200. Epub 2004 May 13. J Biol Chem. 2004. PMID: 15143069 Free article.

Role of mitogen-activated protein kinase in the regulation of transforming growth factor-beta-induced fibronectin accumulation in cultured renal interstitial fibroblasts.

Suzuki H, Uchida K, Nitta K, Nihei H. Suzuki H, et al. Clin Exp Nephrol. 2004 Sep;8(3):188-95. doi: 10.1007/s10157-004-0297-8. Clin Exp Nephrol. 2004. PMID: 15480895

Transforming growth factor-beta inhibition of insulin-like growth factor-binding protein-5 synthesis in skeletal muscle cells involves a c-Jun N-terminal kinase-dependent pathway.

Rousse S, Lallemand F, Montarras D, Pinset C, Mazars A, Prunier C, Atfi A, Dubois C. Rousse S, et al. J Biol Chem. 2001 Dec 14;276(50):46961-7. doi: 10.1074/jbc.M104440200. Epub 2001 Oct 11. J Biol Chem. 2001. PMID: 11598109 Free article.

Role of MAP kinases and their cross-talk in TGF-beta1-induced apoptosis in FaO rat hepatoma cell line.

Park HJ, Kim BC, Kim SJ, Choi KS. Park HJ, et al. Hepatology. 2002 Jun;35(6):1360-71. doi: 10.1053/jhep.2002.33205. Hepatology. 2002. PMID: 12029621

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