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Items: 1 to 20 of 1765

1.
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Combined effects of tamoxifen and a chimeric humanized single chain antibody against the type I IGF receptor on breast tumor growth in vivo.

Ye JJ, Liang SJ, Guo N, Li SL, Wu AM, Giannini S, Sachdev D, Yee D, Brünner N, Ikle D, Fujita-Yamaguchi Y.

Horm Metab Res. 2003 Nov-Dec;35(11-12):836-42.

PMID:
14710366
4.
5.

A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.

Burtrum D, Zhu Z, Lu D, Anderson DM, Prewett M, Pereira DS, Bassi R, Abdullah R, Hooper AT, Koo H, Jimenez X, Johnson D, Apblett R, Kussie P, Bohlen P, Witte L, Hicklin DJ, Ludwig DL.

Cancer Res. 2003 Dec 15;63(24):8912-21.

6.

Mechanisms of antibody-mediated insulin-like growth factor I receptor (IGF-IR) down-regulation in MCF-7 breast cancer cells.

Ohtani M, Numazaki M, Yajima Y, Fujita-Yamaguchi Y.

Biosci Trends. 2009 Aug;3(4):131-8.

7.

Single-chain antibodies against human insulin-like growth factor I receptor: expression, purification, and effect on tumor growth.

Li SL, Liang SJ, Guo N, Wu AM, Fujita-Yamaguchi Y.

Cancer Immunol Immunother. 2000 Jul;49(4-5):243-52.

PMID:
10941907
9.

Re-expression of estrogen receptor alpha in estrogen receptor alpha-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth.

Oesterreich S, Zhang P, Guler RL, Sun X, Curran EM, Welshons WV, Osborne CK, Lee AV.

Cancer Res. 2001 Aug 1;61(15):5771-7.

10.
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Effects of insulin-like growth factors (IGFs) and IGF receptor antibodies on the proliferation of human breast cancer cells.

De Leon DD, Wilson DM, Powers M, Rosenfeld RG.

Growth Factors. 1992;6(4):327-36.

PMID:
1340210
12.
13.

Recombinant insulin-like growth factor binding protein-1 inhibits IGF-I, serum, and estrogen-dependent growth of MCF-7 human breast cancer cells.

Figueroa JA, Sharma J, Jackson JG, McDermott MJ, Hilsenbeck SG, Yee D.

J Cell Physiol. 1993 Nov;157(2):229-36.

PMID:
7693722
14.
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Growth-inhibitory effects of human anti-insulin-like growth factor-I receptor antibody (A12) in an orthotopic nude mouse model of anaplastic thyroid carcinoma.

Wang Z, Chakravarty G, Kim S, Yazici YD, Younes MN, Jasser SA, Santillan AA, Bucana CD, El-Naggar AK, Myers JN.

Clin Cancer Res. 2006 Aug 1;12(15):4755-65.

17.

Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells.

Lee AV, Weng CN, Jackson JG, Yee D.

J Endocrinol. 1997 Jan;152(1):39-47.

PMID:
9014838
19.

An inhibitory function for JNK in the regulation of IGF-I signaling in breast cancer.

Mamay CL, Mingo-Sion AM, Wolf DM, Molina MD, Van Den Berg CL.

Oncogene. 2003 Jan 30;22(4):602-14.

PMID:
12555073

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