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Items: 1 to 20 of 104

1.

CDR3 loop flexibility contributes to the degeneracy of TCR recognition.

Reiser JB, Darnault C, Grégoire C, Mosser T, Mazza G, Kearney A, van der Merwe PA, Fontecilla-Camps JC, Housset D, Malissen B.

Nat Immunol. 2003 Mar;4(3):241-7. Epub 2003 Feb 3.

PMID:
12563259
2.

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition.

Borg NA, Ely LK, Beddoe T, Macdonald WA, Reid HH, Clements CS, Purcell AW, Kjer-Nielsen L, Miles JJ, Burrows SR, McCluskey J, Rossjohn J.

Nat Immunol. 2005 Feb;6(2):171-80. Epub 2005 Jan 9.

PMID:
15640805
3.

Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry.

Sami M, Rizkallah PJ, Dunn S, Molloy P, Moysey R, Vuidepot A, Baston E, Todorov P, Li Y, Gao F, Boulter JM, Jakobsen BK.

Protein Eng Des Sel. 2007 Aug;20(8):397-403. Epub 2007 Jul 20.

PMID:
17644531
4.

Crystal structure of a T cell receptor bound to an allogeneic MHC molecule.

Reiser JB, Darnault C, Guimezanes A, Grégoire C, Mosser T, Schmitt-Verhulst AM, Fontecilla-Camps JC, Malissen B, Housset D, Mazza G.

Nat Immunol. 2000 Oct;1(4):291-7. Erratum in: Nat Immunol 2000 Nov;1(5):447.

PMID:
11017099
5.
6.

High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3.

Chlewicki LK, Holler PD, Monti BC, Clutter MR, Kranz DM.

J Mol Biol. 2005 Feb 11;346(1):223-39. Epub 2004 Dec 22.

PMID:
15663940
7.

A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex.

Reiser JB, Grégoire C, Darnault C, Mosser T, Guimezanes A, Schmitt-Verhulst AM, Fontecilla-Camps JC, Mazza G, Malissen B, Housset D.

Immunity. 2002 Mar;16(3):345-54.

8.

How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides?

Mazza C, Auphan-Anezin N, Gregoire C, Guimezanes A, Kellenberger C, Roussel A, Kearney A, van der Merwe PA, Schmitt-Verhulst AM, Malissen B.

EMBO J. 2007 Apr 4;26(7):1972-83. Epub 2007 Mar 15.

9.

TCR scanning of peptide/MHC through complementary matching of receptor and ligand molecular flexibility.

Hawse WF, De S, Greenwood AI, Nicholson LK, Zajicek J, Kovrigin EL, Kranz DM, Garcia KC, Baker BM.

J Immunol. 2014 Mar 15;192(6):2885-91. doi: 10.4049/jimmunol.1302953. Epub 2014 Feb 12.

10.

Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor.

Hare BJ, Wyss DF, Osburne MS, Kern PS, Reinherz EL, Wagner G.

Nat Struct Biol. 1999 Jun;6(6):574-81.

PMID:
10360364
11.

Comparison of CDR3 length among thymocyte subpopulations: impacts of MHC and BV segment on the CDR3 shortening.

Matsutani T, Ohmori T, Ogata M, Soga H, Kasahara S, Yoshioka T, Suzuki R, Itoh T.

Mol Immunol. 2007 Mar;44(9):2378-87. Epub 2006 Dec 6.

PMID:
17156844
12.

Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.

Velloso LM, Michaëlsson J, Ljunggren HG, Schneider G, Achour A.

J Immunol. 2004 May 1;172(9):5504-11.

13.

T cell receptors: affinities, cross-reactivities, and a conformer model.

Holler PD, Kranz DM.

Mol Immunol. 2004 Feb;40(14-15):1027-31. Review.

PMID:
15036906
14.

Antigen recognition determinants of gammadelta T cell receptors.

Shin S, El-Diwany R, Schaffert S, Adams EJ, Garcia KC, Pereira P, Chien YH.

Science. 2005 Apr 8;308(5719):252-5.

15.

Conformational changes and flexibility in T-cell receptor recognition of peptide-MHC complexes.

Armstrong KM, Piepenbrink KH, Baker BM.

Biochem J. 2008 Oct 15;415(2):183-96. doi: 10.1042/BJ20080850. Review.

16.
17.

Structural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by Vα CDR3.

Deng L, Langley RJ, Wang Q, Topalian SL, Mariuzza RA.

Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14960-5. doi: 10.1073/pnas.1207186109. Epub 2012 Aug 28.

18.

T cell receptor recognition via cooperative conformational plasticity.

Gagnon SJ, Borbulevych OY, Davis-Harrison RL, Turner RV, Damirjian M, Wojnarowicz A, Biddison WE, Baker BM.

J Mol Biol. 2006 Oct 13;363(1):228-43. Epub 2006 Aug 22.

PMID:
16962135
19.

Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor.

Rudolph MG, Huang M, Teyton L, Wilson IA.

J Mol Biol. 2001 Nov 16;314(1):1-8.

PMID:
11724527
20.

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