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Items: 1 to 20 of 82

1.

Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization.

Viglietto G, Motti ML, Fusco A.

Cell Cycle. 2002 Nov-Dec;1(6):394-400. Review.

PMID:
12548012
2.

Are p27 and p21 cytoplasmic oncoproteins?

Blagosklonny MV.

Cell Cycle. 2002 Nov-Dec;1(6):391-3. Review.

PMID:
12548011
3.

p27(kip1) functional regulation in human cancer: a potential target for therapeutic designs.

Belletti B, Nicoloso MS, Schiappacassi M, Chimienti E, Berton S, Lovat F, Colombatti A, Baldassarre G.

Curr Med Chem. 2005;12(14):1589-605. Review.

PMID:
16022660
4.

Keeping p27(Kip1) in the cytoplasm: a second front in cancer's war on p27.

Reed SI.

Cell Cycle. 2002 Nov-Dec;1(6):389-90. Review. No abstract available.

PMID:
12548010
5.

Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1).

Martín A, Odajima J, Hunt SL, Dubus P, Ortega S, Malumbres M, Barbacid M.

Cancer Cell. 2005 Jun;7(6):591-8.

6.

Overexpression of p27(Kip1) induces growth arrest and apoptosis in an oral cancer cell line.

Supriatno, Harada K, Hoque MO, Bando T, Yoshida H, Sato M.

Oral Oncol. 2002 Oct;38(7):730-6.

PMID:
12167427
7.

p27kip1 contributions to cancer.

Nho RS, Sheaff RJ.

Prog Cell Cycle Res. 2003;5:249-59. Review.

PMID:
14593719
8.

p27 deregulation in breast cancer: prognostic significance and implications for therapy.

Alkarain A, Jordan R, Slingerland J.

J Mammary Gland Biol Neoplasia. 2004 Jan;9(1):67-80. Review.

PMID:
15082919
9.

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.

Viglietto G, Motti ML, Bruni P, Melillo RM, D'Alessio A, Califano D, Vinci F, Chiappetta G, Tsichlis P, Bellacosa A, Fusco A, Santoro M.

Nat Med. 2002 Oct;8(10):1136-44. Epub 2002 Sep 16.

PMID:
12244303
10.

Down-regulation of Cdk inhibitor p27 in oral squamous cell carcinoma.

Kudo Y, Kitajima S, Ogawa I, Miyauchi M, Takata T.

Oral Oncol. 2005 Feb;41(2):105-16. Review.

PMID:
15695111
11.

Cyclin dependent kinase inhibitor p27(Kip1) is upregulated by hypoxia via an ARNT dependent pathway.

Wang G, Reisdorph R, Clark RE Jr, Miskimins R, Lindahl R, Miskimins WK.

J Cell Biochem. 2003 Oct 15;90(3):548-60.

PMID:
14523989
12.

Loss of the cell cycle inhibitors p21(Cip1) and p27(Kip1) enhances tumorigenesis in knockout mouse models.

Jackson RJ, Adnane J, Coppola D, Cantor A, Sebti SM, Pledger WJ.

Oncogene. 2002 Dec 5;21(55):8486-97.

13.

Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells.

Koga H, Harada M, Ohtsubo M, Shishido S, Kumemura H, Hanada S, Taniguchi E, Yamashita K, Kumashiro R, Ueno T, Sata M.

Hepatology. 2003 May;37(5):1086-96.

PMID:
12717389
14.

The function of p27 KIP1 during tumor development.

Lee J, Kim SS.

Exp Mol Med. 2009 Nov 30;41(11):765-71. doi: 10.3858/emm.2009.41.11.102. Review.

15.

p27(kip1) expression in rectal cancer correlates with disease-free survival.

Günther K, Jung A, Völker U, Meyer M, Brabletz T, Matzel KE, Reymond MA, Kirchner T, Hohenberger W.

J Surg Res. 2000 Jul;92(1):78-84.

PMID:
10864486
16.

Deregulated degradation of the cdk inhibitor p27 and malignant transformation.

Bloom J, Pagano M.

Semin Cancer Biol. 2003 Feb;13(1):41-7. Review.

PMID:
12507555
18.

Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions.

McAllister SS, Becker-Hapak M, Pintucci G, Pagano M, Dowdy SF.

Mol Cell Biol. 2003 Jan;23(1):216-28.

19.

Rapid turnover of cell-cycle regulators found in Mirk/dyrk1B transfectants.

Ewton DZ, Lee K, Deng X, Lim S, Friedman E.

Int J Cancer. 2003 Jan 1;103(1):21-8.

20.

Protein profiling: a possible molecular mechanism to mislocalization and down-expression of p27(Kip1) in tumor cells.

Guan X, Chen L, Wang J.

Med Hypotheses. 2007;69(3):580-3. Epub 2007 Mar 13.

PMID:
17360130

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