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Items: 1 to 20 of 266

1.

Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene.

Mikkola HK, Klintman J, Yang H, Hock H, Schlaeger TM, Fujiwara Y, Orkin SH.

Nature. 2003 Jan 30;421(6922):547-51. Epub 2003 Jan 19.

PMID:
12540851
2.

Selective rescue of early haematopoietic progenitors in Scl(-/-) mice by expressing Scl under the control of a stem cell enhancer.

Sánchez MJ, Bockamp EO, Miller J, Gambardella L, Green AR.

Development. 2001 Dec;128(23):4815-27.

3.

SCL is required for normal function of short-term repopulating hematopoietic stem cells.

Curtis DJ, Hall MA, Van Stekelenburg LJ, Robb L, Jane SM, Begley CG.

Blood. 2004 May 1;103(9):3342-8. Epub 2004 Jan 15.

4.

Stem cell leukemia protein directs hematopoietic stem cell fate.

Kunisato A, Chiba S, Saito T, Kumano K, Nakagami-Yamaguchi E, Yamaguchi T, Hirai H.

Blood. 2004 May 1;103(9):3336-41. Epub 2004 Jan 15.

5.

SCL expression at critical points in human hematopoietic lineage commitment.

Zhang Y, Payne KJ, Zhu Y, Price MA, Parrish YK, Zielinska E, Barsky LW, Crooks GM.

Stem Cells. 2005 Jun-Jul;23(6):852-60.

6.
7.

Enforced TAL-1 expression stimulates primitive, erythroid and megakaryocytic progenitors but blocks the granulopoietic differentiation program.

Valtieri M, Tocci A, Gabbianelli M, Luchetti L, Masella B, Vitelli L, Botta R, Testa U, Condorelli GL, Peschle C.

Cancer Res. 1998 Feb 1;58(3):562-9.

8.

Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1)-dependent window during hematopoietic stem-cell development.

Schlaeger TM, Mikkola HK, Gekas C, Helgadottir HB, Orkin SH.

Blood. 2005 May 15;105(10):3871-4. Epub 2005 Jan 27.

9.

An SCL 3' enhancer targets developing endothelium together with embryonic and adult haematopoietic progenitors.

Sánchez M, Göttgens B, Sinclair AM, Stanley M, Begley CG, Hunter S, Green AR.

Development. 1999 Sep;126(17):3891-904.

10.
11.

Opposing effects of the basic helix-loop-helix transcription factor SCL on erythroid and monocytic differentiation.

Hoang T, Paradis E, Brady G, Billia F, Nakahara K, Iscove NN, Kirsch IR.

Blood. 1996 Jan 1;87(1):102-11.

12.

The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages.

Porcher C, Swat W, Rockwell K, Fujiwara Y, Alt FW, Orkin SH.

Cell. 1996 Jul 12;86(1):47-57.

13.
14.

Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1.

Zeuner A, Eramo A, Testa U, Felli N, Pelosi E, Mariani G, Srinivasula SM, Alnemri ES, Condorelli G, Peschle C, De Maria R.

Cell Death Differ. 2003 Aug;10(8):905-13.

15.

Distinct mechanisms direct SCL/tal-1 expression in erythroid cells and CD34 positive primitive myeloid cells.

Bockamp EO, McLaughlin F, Göttgens B, Murrell AM, Elefanty AG, Green AR.

J Biol Chem. 1997 Mar 28;272(13):8781-90.

16.

The SCL/TAL1 gene: roles in normal and malignant haematopoiesis.

Robb L, Begley CG.

Bioessays. 1997 Jul;19(7):607-13. Review.

PMID:
9230693
17.

Expression of tal-1 and GATA-binding proteins during human hematopoiesis.

Mouthon MA, Bernard O, Mitjavila MT, Romeo PH, Vainchenker W, Mathieu-Mahul D.

Blood. 1993 Feb 1;81(3):647-55.

18.

The scl +18/19 stem cell enhancer is not required for hematopoiesis: identification of a 5' bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1.

Göttgens B, Broccardo C, Sanchez MJ, Deveaux S, Murphy G, Göthert JR, Kotsopoulou E, Kinston S, Delaney L, Piltz S, Barton LM, Knezevic K, Erber WN, Begley CG, Frampton J, Green AR.

Mol Cell Biol. 2004 Mar;24(5):1870-83.

20.

Ectopic expression of TAL-1 protein in Ly-6E.1-htal-1 transgenic mice induces defects in B- and T-lymphoid differentiation.

Goardon N, Schuh A, Hajar I, Ma X, Jouault H, Dzierzak E, Roméo PH, Maouche-Chrétien L.

Blood. 2002 Jul 15;100(2):491-500.

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