Similar articles for PMID: 12538454

Year	Number of Results
1944	1
1987	1
1988	1
1990	3
1991	3
1992	6
1993	3
1994	2
1995	5
1996	8
1997	7
1998	9
1999	9
2000	18
2001	13
2002	13
2003	16
2004	8
2005	9
2006	8
2007	12
2008	4
2009	8
2010	4
2011	7
2012	3
2013	1
2014	2
2015	3
2016	2
2017	1
2018	2
2020	4
2021	2
2022	4
2023	2
2024	0

1

Repeated administrations of interleukin (IL)-12 are associated with persistently elevated plasma levels of IL-10 and declining IFN-gamma, tumor necrosis factor-alpha, IL-6, and IL-8 responses.

Portielje JE, Lamers CH, Kruit WH, Sparreboom A, Bolhuis RL, Stoter G, Huber C, Gratama JW. Portielje JE, et al. Clin Cancer Res. 2003 Jan;9(1):76-83. Clin Cancer Res. 2003. PMID: 12538454 Clinical Trial.

2

Circulating cytokines in patients with metastatic cancer treated with recombinant interleukin 2 and lymphokine-activated killer cells.

Gemlo BT, Palladino MA Jr, Jaffe HS, Espevik TP, Rayner AA. Gemlo BT, et al. Cancer Res. 1988 Oct 15;48(20):5864-7. Cancer Res. 1988. PMID: 3139285 Clinical Trial.

3

Hypercytokinemia and hyperactivation of phospho-p38 mitogen-activated protein kinase in severe human influenza A virus infection.

Lee N, Wong CK, Chan PK, Lun SW, Lui G, Wong B, Hui DS, Lam CW, Cockram CS, Choi KW, Yeung AC, Tang JW, Sung JJ. Lee N, et al. Clin Infect Dis. 2007 Sep 15;45(6):723-31. doi: 10.1086/520981. Epub 2007 Aug 8. Clin Infect Dis. 2007. PMID: 17712756

4

Down-regulation of the pharmacokinetic-pharmacodynamic response to interleukin-12 during long-term administration to patients with renal cell carcinoma and evaluation of the mechanism of this "adaptive response" in mice.

Rakhit A, Yeon MM, Ferrante J, Fettner S, Nadeau R, Motzer R, Bukowski R, Carvajal DM, Wilkinson VL, Presky DH, Magram J, Gately MK. Rakhit A, et al. Clin Pharmacol Ther. 1999 Jun;65(6):615-29. doi: 10.1016/S0009-9236(99)90083-8. Clin Pharmacol Ther. 1999. PMID: 10391667 Clinical Trial.

5

Depressed interleukin-12-producing activity by monocytes correlates with adverse clinical course and a shift toward Th2-type lymphocyte pattern in severely injured male trauma patients.

Spolarics Z, Siddiqi M, Siegel JH, Garcia ZC, Stein DS, Denny T, Deitch EA. Spolarics Z, et al. Crit Care Med. 2003 Jun;31(6):1722-9. doi: 10.1097/01.CCM.0000063579.43470.AA. Crit Care Med. 2003. PMID: 12794411

6

A dose-escalation and pharmacokinetic study of subcutaneously administered recombinant human interleukin 12 and its biological effects in Japanese patients with advanced malignancies.

Ohno R, Yamaguchi Y, Toge T, Kinouchi T, Kotake T, Shibata M, Kiyohara Y, Ikeda S, Fukui I, Gohchi A, Sugiyama Y, Saji S, Hazama S, Oka M, Ohnishi K, Ohhashi Y, Tsukagoshi S, Taguchi T. Ohno R, et al. Clin Cancer Res. 2000 Jul;6(7):2661-9. Clin Cancer Res. 2000. PMID: 10914707 Clinical Trial.

7

TH1/TH2 serum cytokine profiles and soluble TNF-receptor response in patients with chronic hepatitis C during recombinant human interleukin-12 (rHuIL-12) treatment.

Teuber G, Rossol S, Lee JH, Dietrich CF, Zeuzem S. Teuber G, et al. Z Gastroenterol. 2002 Jul;40(7):487-95. doi: 10.1055/s-2002-32804. Z Gastroenterol. 2002. PMID: 12122596

8

Functional analysis of tumor-infiltrating leukocytes in breast cancer patients.

Wong PY, Staren ED, Tereshkova N, Braun DP. Wong PY, et al. J Surg Res. 1998 Apr;76(1):95-103. doi: 10.1006/jsre.1998.5301. J Surg Res. 1998. PMID: 9695747

9

Phase I study of subcutaneously administered recombinant human interleukin 12 in patients with advanced renal cell cancer.

Portielje JE, Kruit WH, Schuler M, Beck J, Lamers CH, Stoter G, Huber C, de Boer-Dennert M, Rakhit A, Bolhuis RL, Aulitzky WE. Portielje JE, et al. Clin Cancer Res. 1999 Dec;5(12):3983-9. Clin Cancer Res. 1999. PMID: 10632329 Clinical Trial.

10

Phase I trial of twice-weekly intravenous interleukin 12 in patients with metastatic renal cell cancer or malignant melanoma: ability to maintain IFN-gamma induction is associated with clinical response.

Gollob JA, Mier JW, Veenstra K, McDermott DF, Clancy D, Clancy M, Atkins MB. Gollob JA, et al. Clin Cancer Res. 2000 May;6(5):1678-92. Clin Cancer Res. 2000. PMID: 10815886 Clinical Trial.

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