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Items: 1 to 20 of 131

1.

Structural determinants of integrin recognition by talin.

García-Alvarez B, de Pereda JM, Calderwood DA, Ulmer TS, Critchley D, Campbell ID, Ginsberg MH, Liddington RC.

Mol Cell. 2003 Jan;11(1):49-58.

2.

An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding.

Oxley CL, Anthis NJ, Lowe ED, Vakonakis I, Campbell ID, Wegener KL.

J Biol Chem. 2008 Feb 29;283(9):5420-6. Epub 2007 Dec 21.

3.

The extreme C-terminal region of kindlin-2 is critical to its regulation of integrin activation.

Hirbawi J, Bialkowska K, Bledzka KM, Liu J, Fukuda K, Qin J, Plow EF.

J Biol Chem. 2017 Aug 25;292(34):14258-14269. doi: 10.1074/jbc.M117.776195. Epub 2017 Jun 26.

PMID:
28652408
4.

The phosphotyrosine binding-like domain of talin activates integrins.

Calderwood DA, Yan B, de Pereda JM, Alvarez BG, Fujioka Y, Liddington RC, Ginsberg MH.

J Biol Chem. 2002 Jun 14;277(24):21749-58. Epub 2002 Apr 3.

5.

A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.

Song X, Yang J, Hirbawi J, Ye S, Perera HD, Goksoy E, Dwivedi P, Plow EF, Zhang R, Qin J.

Cell Res. 2012 Nov;22(11):1533-45. doi: 10.1038/cr.2012.97. Epub 2012 Jun 19.

6.

Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment.

Moore DT, Nygren P, Jo H, Boesze-Battaglia K, Bennett JS, DeGrado WF.

Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):793-8. doi: 10.1073/pnas.1117220108. Epub 2011 Dec 30.

7.

Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit.

Ulmer TS, Calderwood DA, Ginsberg MH, Campbell ID.

Biochemistry. 2003 Jul 15;42(27):8307-12.

PMID:
12846579
8.

Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.

Calderwood DA, Fujioka Y, de Pereda JM, García-Alvarez B, Nakamoto T, Margolis B, McGlade CJ, Liddington RC, Ginsberg MH.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2272-7. Epub 2003 Feb 26.

9.

The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins.

Bouaouina M, Lad Y, Calderwood DA.

J Biol Chem. 2008 Mar 7;283(10):6118-25. doi: 10.1074/jbc.M709527200. Epub 2007 Dec 28.

10.

The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation.

Goult BT, Bouaouina M, Harburger DS, Bate N, Patel B, Anthis NJ, Campbell ID, Calderwood DA, Barsukov IL, Roberts GC, Critchley DR.

J Mol Biol. 2009 Dec 18;394(5):944-56. doi: 10.1016/j.jmb.2009.09.061. Epub 2009 Oct 3.

11.

Structural basis of integrin activation by talin.

Wegener KL, Partridge AW, Han J, Pickford AR, Liddington RC, Ginsberg MH, Campbell ID.

Cell. 2007 Jan 12;128(1):171-82.

12.

The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges.

Rodius S, Chaloin O, Moes M, Schaffner-Reckinger E, Landrieu I, Lippens G, Lin M, Zhang J, Kieffer N.

J Biol Chem. 2008 Aug 29;283(35):24212-23. doi: 10.1074/jbc.M709704200. Epub 2008 Jun 23.

13.

Epigallocatechin gallate has pleiotropic effects on transmembrane signaling by altering the embedding of transmembrane domains.

Ye F, Yang C, Kim J, MacNevin CJ, Hahn KM, Park D, Ginsberg MH, Kim C.

J Biol Chem. 2017 Jun 16;292(24):9858-9864. doi: 10.1074/jbc.C117.787309. Epub 2017 May 9.

PMID:
28487468
14.

Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain.

Yan B, Calderwood DA, Yaspan B, Ginsberg MH.

J Biol Chem. 2001 Jul 27;276(30):28164-70. Epub 2001 May 29.

15.

Vinculin regulates assembly of talin: β3 integrin complexes.

Nanda SY, Hoang T, Patel P, Zhang H.

J Cell Biochem. 2014 Jun;115(6):1206-16. doi: 10.1002/jcb.24772.

PMID:
24446374
16.

The molecular basis of filamin binding to integrins and competition with talin.

Kiema T, Lad Y, Jiang P, Oxley CL, Baldassarre M, Wegener KL, Campbell ID, Ylänne J, Calderwood DA.

Mol Cell. 2006 Feb 3;21(3):337-47.

17.

Talin controls integrin activation.

Calderwood DA.

Biochem Soc Trans. 2004 Jun;32(Pt3):434-7. Review.

PMID:
15157154
18.

Structural diversity in integrin/talin interactions.

Anthis NJ, Wegener KL, Critchley DR, Campbell ID.

Structure. 2010 Dec 8;18(12):1654-66. doi: 10.1016/j.str.2010.09.018.

19.

Beta integrin tyrosine phosphorylation is a conserved mechanism for regulating talin-induced integrin activation.

Anthis NJ, Haling JR, Oxley CL, Memo M, Wegener KL, Lim CJ, Ginsberg MH, Campbell ID.

J Biol Chem. 2009 Dec 25;284(52):36700-10. doi: 10.1074/jbc.M109.061275. Epub 2009 Oct 20.

20.

Crystal structure of the talin integrin binding domain 2.

Cheung TY, Fairchild MJ, Zarivach R, Tanentzapf G, Van Petegem F.

J Mol Biol. 2009 Apr 10;387(4):787-93.

PMID:
19340939

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