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Items: 1 to 20 of 100

1.
2.

NAD+ ameliorates inflammation-induced epithelial barrier dysfunction in cultured enterocytes and mouse ileal mucosa.

Han X, Uchiyama T, Sappington PL, Yaguchi A, Yang R, Fink MP, Delude RL.

J Pharmacol Exp Ther. 2003 Nov;307(2):443-9.

3.

Ethyl pyruvate provides durable protection against inflammation-induced intestinal epithelial barrier dysfunction.

Sappington PL, Fink ME, Yang R, Delude RL, Fink MP.

Shock. 2003 Dec;20(6):521-8.

PMID:
14625476
4.

HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and impairs intestinal barrier function in mice.

Sappington PL, Yang R, Yang H, Tracey KJ, Delude RL, Fink MP.

Gastroenterology. 2002 Sep;123(3):790-802.

PMID:
12198705
5.

Increased iNOS activity is essential for pulmonary epithelial tight junction dysfunction in endotoxemic mice.

Han X, Fink MP, Uchiyama T, Yang R, Delude RL.

Am J Physiol Lung Cell Mol Physiol. 2004 Feb;286(2):L259-67.

6.
7.

Increased iNOS activity is essential for hepatic epithelial tight junction dysfunction in endotoxemic mice.

Han X, Fink MP, Uchiyama T, Yang R, Delude RL.

Am J Physiol Gastrointest Liver Physiol. 2004 Jan;286(1):G126-36.

8.

Cytokine-induced intestinal epithelial hyperpermeability: role of nitric oxide.

Chavez AM, Menconi MJ, Hodin RA, Fink MP.

Crit Care Med. 1999 Oct;27(10):2246-51.

PMID:
10548215
10.

Ethyl pyruvate ameliorates acute alcohol-induced liver injury and inflammation in mice.

Yang R, Han X, Delude RL, Fink MP.

J Lab Clin Med. 2003 Nov;142(5):322-31.

PMID:
14647036
11.

Dose-dependent effects of ethyl pyruvate in mice subjected to mesenteric ischemia and reperfusion.

Uchiyama T, Delude RL, Fink MP.

Intensive Care Med. 2003 Nov;29(11):2050-8.

PMID:
12955182
12.

Ethyl pyruvate modulates inflammatory gene expression in mice subjected to hemorrhagic shock.

Yang R, Gallo DJ, Baust JJ, Uchiyama T, Watkins SK, Delude RL, Fink MP.

Am J Physiol Gastrointest Liver Physiol. 2002 Jul;283(1):G212-21.

13.

Ethyl pyruvate ameliorates liver injury secondary to severe acute pancreatitis.

Yang R, Shaufl AL, Killeen ME, Fink MP.

J Surg Res. 2009 May 15;153(2):302-9. doi: 10.1016/j.jss.2008.04.004.

PMID:
19027919
14.

The ethyl pyruvate analogues, diethyl oxaloproprionate, 2-acetamidoacrylate, and methyl-2-acetamidoacrylate, exhibit anti-inflammatory properties in vivo and/or in vitro.

Sappington PL, Cruz RJ Jr, Harada T, Yang R, Han Y, Englert JA, Ajami AA, Killeen ME, Delude RL, Fink MP.

Biochem Pharmacol. 2005 Nov 25;70(11):1579-92.

PMID:
16226725
16.

Phosphodiesterase inhibition attenuates alterations to the tight junction proteins occludin and ZO-1 in immunostimulated Caco-2 intestinal monolayers.

Costantini TW, Deree J, Loomis W, Putnam JG, Choi S, Baird A, Eliceiri BP, Bansal V, Coimbra R.

Life Sci. 2009 Jan 2;84(1-2):18-22. doi: 10.1016/j.lfs.2008.10.007.

PMID:
18992758
18.

Nitric oxide mediates interferon-gamma-induced hyperpermeability in cultured human intestinal epithelial monolayers.

Unno N, Menconi MJ, Smith M, Fink MP.

Crit Care Med. 1995 Jul;23(7):1170-6.

PMID:
7541323
19.

Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.

Davé SH, Tilstra JS, Matsuoka K, Li F, DeMarco RA, Beer-Stolz D, Sepulveda AR, Fink MP, Lotze MT, Plevy SE.

J Leukoc Biol. 2009 Sep;86(3):633-43. doi: 10.1189/jlb.1008662.

20.

HMGB1 is secreted by immunostimulated enterocytes and contributes to cytomix-induced hyperpermeability of Caco-2 monolayers.

Liu S, Stolz DB, Sappington PL, Macias CA, Killeen ME, Tenhunen JJ, Delude RL, Fink MP.

Am J Physiol Cell Physiol. 2006 Apr;290(4):C990-9.

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