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Items: 1 to 20 of 1357

1.
2.

Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

Fryer JD, Simmons K, Parsadanian M, Bales KR, Paul SM, Sullivan PM, Holtzman DM.

J Neurosci. 2005 Mar 16;25(11):2803-10.

3.

Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease.

Hartman RE, Laurer H, Longhi L, Bales KR, Paul SM, McIntosh TK, Holtzman DM.

J Neurosci. 2002 Dec 1;22(23):10083-7.

4.

Macrophage-mediated degradation of beta-amyloid via an apolipoprotein E isoform-dependent mechanism.

Zhao L, Lin S, Bales KR, Gelfanova V, Koger D, Delong C, Hale J, Liu F, Hunter JM, Paul SM.

J Neurosci. 2009 Mar 18;29(11):3603-12. doi: 10.1523/JNEUROSCI.5302-08.2009.

5.

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation.

Mucke L, Masliah E, Yu GQ, Mallory M, Rockenstein EM, Tatsuno G, Hu K, Kholodenko D, Johnson-Wood K, McConlogue L.

J Neurosci. 2000 Jun 1;20(11):4050-8.

6.
7.

Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.

Brecht WJ, Harris FM, Chang S, Tesseur I, Yu GQ, Xu Q, Dee Fish J, Wyss-Coray T, Buttini M, Mucke L, Mahley RW, Huang Y.

J Neurosci. 2004 Mar 10;24(10):2527-34.

8.

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.

Fagan AM, Watson M, Parsadanian M, Bales KR, Paul SM, Holtzman DM.

Neurobiol Dis. 2002 Apr;9(3):305-18.

PMID:
11950276
9.

Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology.

Baum L, Chen L, Ng HK, Pang CP.

Microsc Res Tech. 2000 Aug 15;50(4):278-81. Review.

PMID:
10936880
10.

Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits.

Yao J, Petanceska SS, Montine TJ, Holtzman DM, Schmidt SD, Parker CA, Callahan MJ, Lipinski WJ, Bisgaier CL, Turner BA, Nixon RA, Martins RN, Ouimet C, Smith JD, Davies P, Laska E, Ehrlich ME, Walker LC, Mathews PM, Gandy S.

J Neurochem. 2004 Aug;90(4):1011-8.

11.

Human apolipoprotein E4 accelerates beta-amyloid deposition in APPsw transgenic mouse brain.

Carter DB, Dunn E, McKinley DD, Stratman NC, Boyle TP, Kuiper SL, Oostveen JA, Weaver RJ, Boller JA, Gurney ME.

Ann Neurol. 2001 Oct;50(4):468-75.

PMID:
11601499
12.
13.

Apolipoprotein E4 decreases whereas apolipoprotein E3 increases the level of secreted amyloid precursor protein after closed head injury.

Ezra Y, Oron L, Moskovich L, Roses AD, Beni SM, Shohami E, Michaelson DM.

Neuroscience. 2003;121(2):315-25.

PMID:
14521991
14.
15.

Cholinergic neuropathology in a mouse model of Alzheimer's disease.

German DC, Yazdani U, Speciale SG, Pasbakhsh P, Games D, Liang CL.

J Comp Neurol. 2003 Aug 4;462(4):371-81.

PMID:
12811807
16.

The interaction of amyloid-beta with ApoE.

Carter DB.

Subcell Biochem. 2005;38:255-72. Review.

PMID:
15709483
17.

Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration.

Buttini M, Orth M, Bellosta S, Akeefe H, Pitas RE, Wyss-Coray T, Mucke L, Mahley RW.

J Neurosci. 1999 Jun 15;19(12):4867-80.

18.

Selective cholinergic denervation, independent from oxidative stress, in a mouse model of Alzheimer's disease.

Aucoin JS, Jiang P, Aznavour N, Tong XK, Buttini M, Descarries L, Hamel E.

Neuroscience. 2005;132(1):73-86.

PMID:
15780468
19.

Modeling Alzheimer's disease in transgenic mice: effect of age and of presenilin1 on amyloid biochemistry and pathology in APP/London mice.

Dewachter I, van Dorpe J, Spittaels K, Tesseur I, Van Den Haute C, Moechars D, Van Leuven F.

Exp Gerontol. 2000 Sep;35(6-7):831-41. Review.

PMID:
11053674
20.

ApoE isoform-specific effects on LTP: blockade by oligomeric amyloid-beta1-42.

Trommer BL, Shah C, Yun SH, Gamkrelidze G, Pasternak ES, Stine WB, Manelli A, Sullivan P, Pasternak JF, LaDu MJ.

Neurobiol Dis. 2005 Feb;18(1):75-82.

PMID:
15649697

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