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Items: 1 to 20 of 94


Long-lasting occupancy of central nicotinic acetylcholine receptors after smoking: a PET study in monkeys.

Valette H, Bottlaender M, Dollé F, Coulon C, Ottaviani M, Syrota A.

J Neurochem. 2003 Jan;84(1):105-11.


Brain nicotinic acetylcholine receptor occupancy: effect of smoking a denicotinized cigarette.

Brody AL, Mandelkern MA, Costello MR, Abrams AL, Scheibal D, Farahi J, London ED, Olmstead RE, Rose JE, Mukhin AG.

Int J Neuropsychopharmacol. 2009 Apr;12(3):305-16. doi: 10.1017/S146114570800922X. Epub 2008 Aug 18.


Cigarette smoking saturates brain alpha 4 beta 2 nicotinic acetylcholine receptors.

Brody AL, Mandelkern MA, London ED, Olmstead RE, Farahi J, Scheibal D, Jou J, Allen V, Tiongson E, Chefer SI, Koren AO, Mukhin AG.

Arch Gen Psychiatry. 2006 Aug;63(8):907-15.


Quantification of smoking-induced occupancy of beta2-nicotinic acetylcholine receptors: estimation of nondisplaceable binding.

Esterlis I, Cosgrove KP, Batis JC, Bois F, Stiklus SM, Perkins E, Seibyl JP, Carson RE, Staley JK.

J Nucl Med. 2010 Aug;51(8):1226-33. doi: 10.2967/jnumed.109.072447. Epub 2010 Jul 21.


Validation of an extracerebral reference region approach for the quantification of brain nicotinic acetylcholine receptors in squirrel monkeys with PET and 2-18F-fluoro-A-85380.

Le Foll B, Chefer SI, Kimes AS, Shumway D, Goldberg SR, Stein EA, Mukhin AG.

J Nucl Med. 2007 Sep;48(9):1492-500. Epub 2007 Aug 17.


Brain β2*-nicotinic acetylcholine receptor occupancy after use of a nicotine inhaler.

Esterlis I, Mitsis EM, Batis JC, Bois F, Picciotto MR, Stiklus SM, Kloczynski T, Perry E, Seibyl JP, McKee S, Staley JK, Cosgrove KP.

Int J Neuropsychopharmacol. 2011 Apr;14(3):389-98. doi: 10.1017/S1461145710001227. Epub 2010 Oct 29.


PET imaging of high-affinity α4β2 nicotinic acetylcholine receptors in humans with 18F-AZAN, a radioligand with optimal brain kinetics.

Wong DF, Kuwabara H, Kim J, Brasic JR, Chamroonrat W, Gao Y, Valentine H, Willis W, Mathur A, McCaul ME, Wand G, Gean EG, Dannals RF, Horti AG.

J Nucl Med. 2013 Aug;54(8):1308-14. doi: 10.2967/jnumed.112.108001. Epub 2013 Jun 25.


In vivo imaging of human cerebral nicotinic acetylcholine receptors with 2-18F-fluoro-A-85380 and PET.

Gallezot JD, Bottlaender M, Grégoire MC, Roumenov D, Deverre JR, Coulon C, Ottaviani M, Dollé F, Syrota A, Valette H.

J Nucl Med. 2005 Feb;46(2):240-7.


Effect of secondhand smoke on occupancy of nicotinic acetylcholine receptors in brain.

Brody AL, Mandelkern MA, London ED, Khan A, Kozman D, Costello MR, Vellios EE, Archie MM, Bascom R, Mukhin AG.

Arch Gen Psychiatry. 2011 Sep;68(9):953-60. doi: 10.1001/archgenpsychiatry.2011.51. Epub 2011 May 2.


PET Imaging of nicotinic acetylcholine receptors in baboons with 18F-AZAN, a radioligand with improved brain kinetics.

Kuwabara H, Wong DF, Gao Y, Valentine H, Holt DP, Ravert HT, Dannals RF, Horti AG.

J Nucl Med. 2012 Jan;53(1):121-9. doi: 10.2967/jnumed.111.092338. Epub 2011 Dec 15.


Imaging nicotinic acetylcholine receptors with fluorine-18-FPH, an epibatidine analog.

Villemagne VL, Horti A, Scheffel U, Ravert HT, Finley P, Clough DJ, London ED, Wagner HN Jr, Dannals RF.

J Nucl Med. 1997 Nov;38(11):1737-41.


In vivo brain imaging of human exposure to nicotine and tobacco.

Sharma A, Brody AL.

Handb Exp Pharmacol. 2009;(192):145-71. doi: 10.1007/978-3-540-69248-5_6. Review.


Acute inhibition of cardiac monoamine oxidase A after tobacco smoke inhalation: validation study of [11C]befloxatone in rats followed by a positron emission tomography application in baboons.

Valette H, Bottlaender M, Dollé F, Coulon C, Ottaviani M, Syrota A.

J Pharmacol Exp Ther. 2005 Jul;314(1):431-6. Epub 2005 Apr 15.


Occupancy of brain nicotinic acetylcholine receptors by nicotine doses equivalent to those obtained when smoking a cigarette.

Ding YS, Volkow ND, Logan J, Garza V, Pappas N, King P, Fowler JS.

Synapse. 2000 Mar 1;35(3):234-7. No abstract available.


Regional differential effects of chronic nicotine on brain alpha 4-containing and alpha 6-containing receptors.

Even N, Cardona A, Soudant M, Corringer PJ, Changeux JP, Cloëz-Tayarani I.

Neuroreport. 2008 Oct 8;19(15):1545-50. doi: 10.1097/WNR.0b013e3283112703.


Characterization of the nicotinic ligand 2-[18F]fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine in vivo.

Valette H, Bottlaender M, Dollé F, Guenther I, Coulon C, Hinnen F, Fuseau C, Ottaviani M, Crouzel C.

Life Sci. 1999;64(5):PL93-7.


Evaluation of 5-(11)C-methyl-A-85380 as an imaging agent for PET investigations of brain nicotinic acetylcholine receptors.

Iida Y, Ogawa M, Ueda M, Tominaga A, Kawashima H, Magata Y, Nishiyama S, Tsukada H, Mukai T, Saji H.

J Nucl Med. 2004 May;45(5):878-84.


Effect of a nicotine vaccine on nicotine binding to β2*-nicotinic acetylcholine receptors in vivo in human tobacco smokers.

Esterlis I, Hannestad JO, Perkins E, Bois F, D'Souza DC, Tyndale RF, Seibyl JP, Hatsukami DM, Cosgrove KP, O'Malley SS.

Am J Psychiatry. 2013 Apr;170(4):399-407. doi: 10.1176/appi.ajp.2012.12060793.

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