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Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice.

Yu C, Wang F, Jin C, Wu X, Chan WK, McKeehan WL.

Am J Pathol. 2002 Dec;161(6):2003-10.


Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis.

Yu C, Wang F, Jin C, Huang X, Miller DL, Basilico C, McKeehan WL.

Am J Pathol. 2003 Oct;163(4):1653-62.


The role of tumor necrosis factor-alpha in liver toxicity, inflammation, and fibrosis induced by carbon tetrachloride.

Simeonova PP, Gallucci RM, Hulderman T, Wilson R, Kommineni C, Rao M, Luster MI.

Toxicol Appl Pharmacol. 2001 Dec 1;177(2):112-20.


Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4.

Yu C, Wang F, Kan M, Jin C, Jones RB, Weinstein M, Deng CX, McKeehan WL.

J Biol Chem. 2000 May 19;275(20):15482-9.


The role of CYP2A5 in liver injury and fibrosis: chemical-specific difference.

Hong F, Si C, Gao P, Cederbaum AI, Xiong H, Lu Y.

Naunyn Schmiedebergs Arch Pharmacol. 2016 Jan;389(1):33-43. doi: 10.1007/s00210-015-1172-8. Epub 2015 Sep 12.


A contradictory role of A1 adenosine receptor in carbon tetrachloride- and bile duct ligation-induced liver fibrosis in mice.

Yang P, Han Z, Chen P, Zhu L, Wang S, Hua Z, Zhang J.

J Pharmacol Exp Ther. 2010 Mar;332(3):747-54. doi: 10.1124/jpet.109.162727. Epub 2009 Dec 10.


Striking LD50 variation associated with fluctuations of CYP2E1-positive cells in hepatic lobule during chronic CCl4 exposure in mice.

Irie H, Asano-Hoshino A, Sekino Y, Nogami M, Kitagawa T, Kanda H.

Virchows Arch. 2010 Apr;456(4):423-31. doi: 10.1007/s00428-009-0872-1. Epub 2010 Feb 13.


Date fruits inhibit hepatocyte apoptosis and modulate the expression of hepatocyte growth factor, cytochrome P450 2E1 and heme oxygenase-1 in carbon tetrachloride-induced liver fibrosis.

Al-Rasheed NM, Attia HA, Mohamad RA, Al-Rasheed NM, Al Fayez M, Al-Amin MA.

Arch Physiol Biochem. 2017 May;123(2):78-92. doi: 10.1080/13813455.2016.1251945. Epub 2016 Dec 14.


Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis.

Huang X, Yang C, Jin C, Luo Y, Wang F, McKeehan WL.

Mol Carcinog. 2009 Jun;48(6):553-62. doi: 10.1002/mc.20494.


Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2.

Ikeda H, Watanabe N, Ishii I, Shimosawa T, Kume Y, Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, Iitsuka S, Fujita R, Omata M, Chun J, Yatomi Y.

J Lipid Res. 2009 Mar;50(3):556-64. doi: 10.1194/jlr.M800496-JLR200. Epub 2008 Oct 27.


Protective effect of L-theanine on carbon tetrachloride-induced acute liver injury in mice.

Jiang W, Gao M, Sun S, Bi A, Xin Y, Han X, Wang L, Yin Z, Luo L.

Biochem Biophys Res Commun. 2012 Jun 1;422(2):344-50. doi: 10.1016/j.bbrc.2012.05.022. Epub 2012 May 11.


Protective effects of cassia seed ethanol extract against carbon tetrachloride-induced liver injury in mice.

Xie Q, Guo FF, Zhou W.

Acta Biochim Pol. 2012;59(2):265-70. Epub 2012 Jun 11.


Delayed liver injury and impaired hepatocyte proliferation after carbon tetrachloride exposure in BPOZ2-deficient mice.

Zhang F, Shu R, Wu X, Zhao X, Feng D, Wang L, Lu S, Liu Q, Xiang Y, Fei J, Huang L, Wang Z.

Toxicol Lett. 2009 Aug 10;188(3):201-7. doi: 10.1016/j.toxlet.2009.04.009. Epub 2009 Apr 23.


Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation.

Xiao J, Liong EC, Ching YP, Chang RC, So KF, Fung ML, Tipoe GL.

J Ethnopharmacol. 2012 Jan 31;139(2):462-70. doi: 10.1016/j.jep.2011.11.033. Epub 2011 Nov 26.


FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver.

Huang X, Yang C, Luo Y, Jin C, Wang F, McKeehan WL.

Diabetes. 2007 Oct;56(10):2501-10. Epub 2007 Jul 30.


Changes in the gene expression associated with carbon tetrachloride-induced liver fibrosis persist after cessation of dosing in mice.

Jiang Y, Liu J, Waalkes M, Kang YJ.

Toxicol Sci. 2004 Jun;79(2):404-10. Epub 2004 Mar 31.


Protective role of estrogen-induced miRNA-29 expression in carbon tetrachloride-induced mouse liver injury.

Zhang Y, Wu L, Wang Y, Zhang M, Li L, Zhu D, Li X, Gu H, Zhang CY, Zen K.

J Biol Chem. 2012 Apr 27;287(18):14851-62. doi: 10.1074/jbc.M111.314922. Epub 2012 Mar 5.


The Cdk inhibitor p21 is required for necrosis, but it inhibits apoptosis following toxin-induced liver injury.

Kwon YH, Jovanovic A, Serfas MS, Tyner AL.

J Biol Chem. 2003 Aug 8;278(32):30348-55. Epub 2003 May 20.

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