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Items: 1 to 20 of 134

1.

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer.

DiTullio RA Jr, Mochan TA, Venere M, Bartkova J, Sehested M, Bartek J, Halazonetis TD.

Nat Cell Biol. 2002 Dec;4(12):998-1002. Erratum in: Nat Cell Biol. 2003 Jan;5(1):84..

PMID:
12447382
2.

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks.

Schultz LB, Chehab NH, Malikzay A, Halazonetis TD.

J Cell Biol. 2000 Dec 25;151(7):1381-90.

3.
4.

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways.

Rappold I, Iwabuchi K, Date T, Chen J.

J Cell Biol. 2001 Apr 30;153(3):613-20. Erratum in: J Cell Biol 2001 Jul 23;154(2):469.

5.

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.

Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A.

J Cell Sci. 2005 Apr 15;118(Pt 8):1629-39. Retraction in: J Cell Sci. 2015 Mar 1;128(5):1064.

6.

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.

Fernandez-Capetillo O, Chen HT, Celeste A, Ward I, Romanienko PJ, Morales JC, Naka K, Xia Z, Camerini-Otero RD, Motoyama N, Carpenter PB, Bonner WM, Chen J, Nussenzweig A.

Nat Cell Biol. 2002 Dec;4(12):993-7.

PMID:
12447390
7.

Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage.

Anderson L, Henderson C, Adachi Y.

Mol Cell Biol. 2001 Mar;21(5):1719-29.

8.

53BP1, an activator of ATM in response to DNA damage.

Mochan TA, Venere M, DiTullio RA Jr, Halazonetis TD.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):945-52.

PMID:
15279780
9.

53BP1, a mediator of the DNA damage checkpoint.

Wang B, Matsuoka S, Carpenter PB, Elledge SJ.

Science. 2002 Nov 15;298(5597):1435-8.

10.
11.

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice.

Ward IM, Minn K, van Deursen J, Chen J.

Mol Cell Biol. 2003 Apr;23(7):2556-63.

12.

Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage.

Sanz-GarcĂ­a M, Monsalve DM, Sevilla A, Lazo PA.

J Biol Chem. 2012 Jul 6;287(28):23757-68. doi: 10.1074/jbc.M112.353102.

13.

Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint.

Silverman J, Takai H, Buonomo SB, Eisenhaber F, de Lange T.

Genes Dev. 2004 Sep 1;18(17):2108-19.

14.

Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.

Brew CT, Aronchik I, Hsu JC, Sheen JH, Dickson RB, Bjeldanes LF, Firestone GL.

Int J Cancer. 2006 Feb 15;118(4):857-68.

15.

Growth of persistent foci of DNA damage checkpoint factors is essential for amplification of G1 checkpoint signaling.

Yamauchi M, Oka Y, Yamamoto M, Niimura K, Uchida M, Kodama S, Watanabe M, Sekine I, Yamashita S, Suzuki K.

DNA Repair (Amst). 2008 Mar 1;7(3):405-17. doi: 10.1016/j.dnarep.2007.11.011.

PMID:
18248856
16.
17.

PTIP regulates 53BP1 and SMC1 at the DNA damage sites.

Wu J, Prindle MJ, Dressler GR, Yu X.

J Biol Chem. 2009 Jul 3;284(27):18078-84. doi: 10.1074/jbc.M109.002527.

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19.

ATM signaling and 53BP1.

Zgheib O, Huyen Y, DiTullio RA Jr, Snyder A, Venere M, Stavridi ES, Halazonetis TD.

Radiother Oncol. 2005 Aug;76(2):119-22. Review.

PMID:
16024119
20.

Protein-protein interactions occur between p53 phosphoforms and ATM and 53BP1 at sites of exogenous DNA damage.

Al Rashid ST, Harding SM, Law C, Coackley C, Bristow RG.

Radiat Res. 2011 May;175(5):588-98. doi: 10.1667/RR2084.1.

PMID:
21361779
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