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Items: 1 to 20 of 110

1.

Restoration of transforming growth factor Beta signaling by functional expression of smad4 induces anoikis.

Ramachandra M, Atencio I, Rahman A, Vaillancourt M, Zou A, Avanzini J, Wills K, Bookstein R, Shabram P.

Cancer Res. 2002 Nov 1;62(21):6045-51.

2.

Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.

Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ.

Clin Cancer Res. 2002 Nov;8(11):3628-38.

3.

Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells.

Chen WB, Lenschow W, Tiede K, Fischer JW, Kalthoff H, Ungefroren H.

J Biol Chem. 2002 Sep 27;277(39):36118-28.

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Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis.

Imai Y, Kurokawa M, Izutsu K, Hangaishi A, Maki K, Ogawa S, Chiba S, Mitani K, Hirai H.

Oncogene. 2001 Jan 4;20(1):88-96.

6.

Adenovirus-mediated gene transfer of dominant-negative Smad4 blocks TGF-beta signaling in pancreatic acinar cells.

Zhang L, Graziano K, Pham T, Logsdon CD, Simeone DM.

Am J Physiol Gastrointest Liver Physiol. 2001 Jun;280(6):G1247-53.

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Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: a tissue microarray study.

Xie W, Mertens JC, Reiss DJ, Rimm DL, Camp RL, Haffty BG, Reiss M.

Cancer Res. 2002 Jan 15;62(2):497-505.

10.

DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells.

de Winter JP, Roelen BA, ten Dijke P, van der Burg B, van den Eijnden-van Raaij AJ.

Oncogene. 1997 Apr 24;14(16):1891-9.

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Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle.

Chiao PJ, Hunt KK, Grau AM, Abramian A, Fleming J, Zhang W, Breslin T, Abbruzzese JL, Evans DB.

Ann N Y Acad Sci. 1999 Jun 30;880:31-7.

PMID:
10415848
15.

TGF-beta-induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines.

Fink SP, Mikkola D, Willson JK, Markowitz S.

Oncogene. 2003 Mar 6;22(9):1317-23.

PMID:
12618756
16.

Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.

Subramanian G, Schwarz RE, Higgins L, McEnroe G, Chakravarty S, Dugar S, Reiss M.

Cancer Res. 2004 Aug 1;64(15):5200-11.

17.

Overexpression of the tumor suppressor gene Smad4/DPC4 induces p21waf1 expression and growth inhibition in human carcinoma cells.

Hunt KK, Fleming JB, Abramian A, Zhang L, Evans DB, Chiao PJ.

Cancer Res. 1998 Dec 15;58(24):5656-61.

18.

The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function.

Zhang Y, Musci T, Derynck R.

Curr Biol. 1997 Apr 1;7(4):270-6.

19.

Smad4-independent regulation of p21/WAF1 by transforming growth factor-beta.

Ijichi H, Otsuka M, Tateishi K, Ikenoue T, Kawakami T, Kanai F, Arakawa Y, Seki N, Shimizu K, Miyazono K, Kawabe T, Omata M.

Oncogene. 2004 Feb 5;23(5):1043-51.

PMID:
14762439
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