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PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.

Pei L, Peng Y, Yang Y, Ling XB, Van Eyndhoven WG, Nguyen KC, Rubin M, Hoey T, Powers S, Li J.

Cancer Res. 2002 Oct 1;62(19):5420-4.


TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.

Hodzic D, Kong C, Wainszelbaum MJ, Charron AJ, Su X, Stahl PD.

Genomics. 2006 Dec;88(6):731-6.


Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases.

Lanzetti L, Palamidessi A, Areces L, Scita G, Di Fiore PP.

Nature. 2004 May 20;429(6989):309-14.


A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells.

Wang L, Yang L, Luo Y, Zheng Y.

J Biol Chem. 2003 Nov 7;278(45):44617-25.


Characterization of a brain-specific Rho GTPase-activating protein, p200RhoGAP.

Moon SY, Zang H, Zheng Y.

J Biol Chem. 2003 Feb 7;278(6):4151-9.


The p44S10 locus, encoding a subunit of the proteasome regulatory particle, is amplified during progression of cutaneous malignant melanoma.

Ren S, Smith MJ, Louro ID, McKie-Bell P, Bani MR, Wagner M, Zochodne B, Redden DT, Grizzle WE, Wang Nd, Smith DI, Herbst RA, Bardenheuer W, Opalka B, Schütte J, Trent JM, Ben-David Y, Ruppert JM.

Oncogene. 2000 Mar 9;19(11):1419-27.


A novel human RasGAP-like gene that maps within the prostate cancer susceptibility locus at chromosome 1q25.

Noto S, Maeda T, Hattori S, Inazawa J, Imamura M, Asaka M, Hatakeyama M.

FEBS Lett. 1998 Dec 11;441(1):127-31.


Translational infidelity and human cancer: role of the PTI-1 oncogene.

Gopalkrishnan RV, Su ZZ, Goldstein NI, Fisher PB.

Int J Biochem Cell Biol. 1999 Jan;31(1):151-62. Review.


The primate-specific protein TBC1D3 is required for optimal macropinocytosis in a novel ARF6-dependent pathway.

Frittoli E, Palamidessi A, Pizzigoni A, Lanzetti L, Garrè M, Troglio F, Troilo A, Fukuda M, Di Fiore PP, Scita G, Confalonieri S.

Mol Biol Cell. 2008 Apr;19(4):1304-16. doi: 10.1091/mbc.E07-06-0594.


PMEPA1, an androgen-regulated NEDD4-binding protein, exhibits cell growth inhibitory function and decreased expression during prostate cancer progression.

Xu LL, Shi Y, Petrovics G, Sun C, Makarem M, Zhang W, Sesterhenn IA, McLeod DG, Sun L, Moul JW, Srivastava S.

Cancer Res. 2003 Aug 1;63(15):4299-304.


Dynamic expression of d-CdGAPr, a novel Drosophila melanogaster gene encoding a GTPase activating protein.

Sagnier T, Grienenberger A, Mariol M, Bérenger H, Pradel J, Graba Y.

Mech Dev. 2000 Jun;94(1-2):267-70.


A highly conserved protein secreted by the prostate cancer cell line PC-3 is expressed in benign and malignant prostate tissue.

Valtonen-André C, Bjartell A, Hellsten R, Lilja H, Härkönen P, Lundwall A.

Biol Chem. 2007 Mar;388(3):289-95.


Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.

Ishibashi K, Kanno E, Itoh T, Fukuda M.

Genes Cells. 2009 Jan;14(1):41-52. doi: 10.1111/j.1365-2443.2008.01251.x.


A prostate-derived cDNA that is mapped to human chromosome 19 encodes a novel protein.

Wang C, McCarty IM, Balazs L, Li Y, Steiner MS.

Biochem Biophys Res Commun. 2002 Aug 16;296(2):281-7.


Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma.

Ching YP, Wong CM, Chan SF, Leung TH, Ng DC, Jin DY, Ng IO.

J Biol Chem. 2003 Mar 21;278(12):10824-30.

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