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Items: 1 to 20 of 113

1.

Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy.

Wu Y, Temple J, Zhang R, Dzhura I, Zhang W, Trimble R, Roden DM, Passier R, Olson EN, Colbran RJ, Anderson ME.

Circulation. 2002 Sep 3;106(10):1288-93.

2.

Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy.

Khoo MS, Li J, Singh MV, Yang Y, Kannankeril P, Wu Y, Grueter CE, Guan X, Oddis CV, Zhang R, Mendes L, Ni G, Madu EC, Yang J, Bass M, Gomez RJ, Wadzinski BE, Olson EN, Colbran RJ, Anderson ME.

Circulation. 2006 Sep 26;114(13):1352-9. Epub 2006 Sep 18.

3.

Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure.

Sag CM, Wadsack DP, Khabbazzadeh S, Abesser M, Grefe C, Neumann K, Opiela MK, Backs J, Olson EN, Brown JH, Neef S, Maier SK, Maier LS.

Circ Heart Fail. 2009 Nov;2(6):664-75. doi: 10.1161/CIRCHEARTFAILURE.109.865279. Epub 2009 Jul 31.

4.

Transgenic CaMKIIdeltaC overexpression uniquely alters cardiac myocyte Ca2+ handling: reduced SR Ca2+ load and activated SR Ca2+ release.

Maier LS, Zhang T, Chen L, DeSantiago J, Brown JH, Bers DM.

Circ Res. 2003 May 2;92(8):904-11. Epub 2003 Apr 3.

5.

CaMKII inhibition reduces isoproterenol-induced ischemia and arrhythmias in hypertrophic mice.

Feng Y, Cheng J, Wei B, Wang Y.

Oncotarget. 2017 Mar 14;8(11):17504-17509. doi: 10.18632/oncotarget.15099.

6.

Calmodulin kinase and L-type calcium channels; a recipe for arrhythmias?

Anderson ME.

Trends Cardiovasc Med. 2004 May;14(4):152-61. Review.

PMID:
15177266
7.

Calcium-calmodulin kinase II mediates digitalis-induced arrhythmias.

Gonano LA, Sepúlveda M, Rico Y, Kaetzel M, Valverde CA, Dedman J, Mattiazzi A, Vila Petroff M.

Circ Arrhythm Electrophysiol. 2011 Dec;4(6):947-57. doi: 10.1161/CIRCEP.111.964908. Epub 2011 Oct 18.

8.

Calmodulin kinase II inhibition shortens action potential duration by upregulation of K+ currents.

Li J, Marionneau C, Zhang R, Shah V, Hell JW, Nerbonne JM, Anderson ME.

Circ Res. 2006 Nov 10;99(10):1092-9. Epub 2006 Oct 12.

9.

Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase.

Curran J, Hinton MJ, Ríos E, Bers DM, Shannon TR.

Circ Res. 2007 Feb 16;100(3):391-8. Epub 2007 Jan 18.

10.

Calcium-calmodulin dependent protein kinase II (CaMKII): a main signal responsible for early reperfusion arrhythmias.

Said M, Becerra R, Valverde CA, Kaetzel MA, Dedman JR, Mundiña-Weilenmann C, Wehrens XH, Vittone L, Mattiazzi A.

J Mol Cell Cardiol. 2011 Dec;51(6):936-44. doi: 10.1016/j.yjmcc.2011.08.010. Epub 2011 Aug 19.

11.

Nonequilibrium reactivation of Na+ current drives early afterdepolarizations in mouse ventricle.

Edwards AG, Grandi E, Hake JE, Patel S, Li P, Miyamoto S, Omens JH, Heller Brown J, Bers DM, McCulloch AD.

Circ Arrhythm Electrophysiol. 2014 Dec;7(6):1205-13. doi: 10.1161/CIRCEP.113.001666. Epub 2014 Sep 18.

12.

Stretch current-induced abnormal impulses in CaMKIIδ knockout mouse ventricular myocytes.

Lai D, Xu L, Cheng J, Guilbert AB, Lim HJ, Fu G, Wang Y.

J Cardiovasc Electrophysiol. 2013 Apr;24(4):457-63. doi: 10.1111/jce.12060. Epub 2012 Dec 21.

13.

Effects of calmodulin-dependent protein kinase II inhibitor, KN-93, on electrophysiological features of rabbit hypertrophic cardiac myocytes.

Ke J, Chen F, Zhang C, Xiao X, Tu J, Dai M, Wang X, Chen B, Chen M.

J Huazhong Univ Sci Technolog Med Sci. 2012 Aug;32(4):485-9. doi: 10.1007/s11596-012-0084-9. Epub 2012 Aug 11.

PMID:
22886958
14.

Calmodulin kinase II inhibition prevents arrhythmic activity induced by alpha and beta adrenergic agonists in rabbit pulmonary veins.

Lo LW, Chen YC, Chen YJ, Wongcharoen W, Lin CI, Chen SA.

Eur J Pharmacol. 2007 Oct 1;571(2-3):197-208. Epub 2007 Jun 13.

PMID:
17612522
15.

miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2.

Terentyev D, Belevych AE, Terentyeva R, Martin MM, Malana GE, Kuhn DE, Abdellatif M, Feldman DS, Elton TS, Györke S.

Circ Res. 2009 Feb 27;104(4):514-21. doi: 10.1161/CIRCRESAHA.108.181651. Epub 2009 Jan 8.

16.

KN-93, A CaMKII inhibitor, suppresses ventricular arrhythmia induced by LQT2 without decreasing TDR.

Wang WL, Zhang SS, Deng J, Zhao JY, Zhao CQ, Lin L, Zhang CT, Lv JG.

J Huazhong Univ Sci Technolog Med Sci. 2013 Oct;33(5):636-9. doi: 10.1007/s11596-013-1172-1. Epub 2013 Oct 20.

PMID:
24142712
17.

Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels.

Wagner S, Dybkova N, Rasenack EC, Jacobshagen C, Fabritz L, Kirchhof P, Maier SK, Zhang T, Hasenfuss G, Brown JH, Bers DM, Maier LS.

J Clin Invest. 2006 Dec;116(12):3127-38. Epub 2006 Nov 22.

18.

Ventricular arrhythmias, increased cardiac calmodulin kinase II expression, and altered repolarization kinetics in ANP receptor deficient mice.

Kirchhof P, Fabritz L, Kilić A, Begrow F, Breithardt G, Kuhn M.

J Mol Cell Cardiol. 2004 May;36(5):691-700.

PMID:
15135664
19.

Calmodulin kinases II and IV and calcineurin are involved in leukemia inhibitory factor-induced cardiac hypertrophy in rats.

Kato T, Sano M, Miyoshi S, Sato T, Hakuno D, Ishida H, Kinoshita-Nakazawa H, Fukuda K, Ogawa S.

Circ Res. 2000 Nov 10;87(10):937-45.

20.

Increased intracellular Ca2+ and SR Ca2+ load contribute to arrhythmias after acidosis in rat heart. Role of Ca2+/calmodulin-dependent protein kinase II.

Said M, Becerra R, Palomeque J, Rinaldi G, Kaetzel MA, Diaz-Sylvester PL, Copello JA, Dedman JR, Mundiña-Weilenmann C, Vittone L, Mattiazzi A.

Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1669-83. doi: 10.1152/ajpheart.00010.2008. Epub 2008 Aug 22.

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