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Mortality and cardiovascular events in patients treated with homocysteine-lowering B vitamins after coronary angiography: a randomized controlled trial.

Ebbing M, Bleie Ø, Ueland PM, Nordrehaug JE, Nilsen DW, Vollset SE, Refsum H, Pedersen EK, Nygård O.

JAMA. 2008 Aug 20;300(7):795-804. doi: 10.1001/jama.300.7.795.


Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease: a randomized trial.

Albert CM, Cook NR, Gaziano JM, Zaharris E, MacFadyen J, Danielson E, Buring JE, Manson JE.

JAMA. 2008 May 7;299(17):2027-36. doi: 10.1001/jama.299.17.2027.


Decreased rate of coronary restenosis after lowering of plasma homocysteine levels.

Schnyder G, Roffi M, Pin R, Flammer Y, Lange H, Eberli FR, Meier B, Turi ZG, Hess OM.

N Engl J Med. 2001 Nov 29;345(22):1593-600.


Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial.

Toole JF, Malinow MR, Chambless LE, Spence JD, Pettigrew LC, Howard VJ, Sides EG, Wang CH, Stampfer M.

JAMA. 2004 Feb 4;291(5):565-75.


Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal disease: a randomized controlled trial.

Jamison RL, Hartigan P, Kaufman JS, Goldfarb DS, Warren SR, Guarino PD, Gaziano JM; Veterans Affairs Site Investigators..

JAMA. 2007 Sep 12;298(10):1163-70. Erratum in: JAMA. 2008 Jul 9;300(2):170.


Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial.

Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) Collaborative Group., Armitage JM, Bowman L, Clarke RJ, Wallendszus K, Bulbulia R, Rahimi K, Haynes R, Parish S, Sleight P, Peto R, Collins R.

JAMA. 2010 Jun 23;303(24):2486-94. doi: 10.1001/jama.2010.840.


Folate therapy and in-stent restenosis after coronary stenting.

Lange H, Suryapranata H, De Luca G, Börner C, Dille J, Kallmayer K, Pasalary MN, Scherer E, Dambrink JH.

N Engl J Med. 2004 Jun 24;350(26):2673-81.


Homocysteine lowering and cardiovascular events after acute myocardial infarction.

Bønaa KH, Njølstad I, Ueland PM, Schirmer H, Tverdal A, Steigen T, Wang H, Nordrehaug JE, Arnesen E, Rasmussen K; NORVIT Trial Investigators..

N Engl J Med. 2006 Apr 13;354(15):1578-88.


Rationale, design and baseline characteristics of a large, simple, randomized trial of combined folic acid and vitamins B6 and B12 in high-risk patients: the Heart Outcomes Prevention Evaluation (HOPE)-2 trial.

Lonn E, Held C, Arnold JM, Probstfield J, McQueen M, Micks M, Pogue J, Sheridan P, Bosch J, Genest J, Yusuf S; HOPE-2 Investigators..

Can J Cardiol. 2006 Jan;22(1):47-53.


Homocysteine lowering with folic acid and B vitamins in vascular disease.

Lonn E, Yusuf S, Arnold MJ, Sheridan P, Pogue J, Micks M, McQueen MJ, Probstfield J, Fodor G, Held C, Genest J Jr; Heart Outcomes Prevention Evaluation (HOPE) 2 Investigators..

N Engl J Med. 2006 Apr 13;354(15):1567-77. Erratum in: N Engl J Med. 2006 Aug 17;355(7):746.


The China Stroke Secondary Prevention Trial (CSSPT) protocol: a double-blinded, randomized, controlled trial of combined folic acid and B vitamins for secondary prevention of stroke.

Liu X, Shi M, Xia F, Han J, Liu Z, Wang B, Yang F, Li L, Wu S, Wang L, Liu N, Lv Y, Zhao G.

Int J Stroke. 2015 Feb;10(2):264-8. doi: 10.1111/ijs.12017.


Interventions for lowering plasma homocysteine levels in dialysis patients.

Nigwekar SU, Kang A, Zoungas S, Cass A, Gallagher MP, Kulshrestha S, Navaneethan SD, Perkovic V, Strippoli GF, Jardine MJ.

Cochrane Database Syst Rev. 2016 May 31;(5):CD004683. doi: 10.1002/14651858.CD004683.pub4. Review.


[Meta-analysis on effect of combined supplementation of folic acid, vitamin B12 and B6 on risk of cardio-cerebrovascular diseases in randomized control trials].

Lan X, Dang SN, Zhao YL, Yan H, Yan H.

Zhonghua Liu Xing Bing Xue Za Zhi. 2016 Jul;37(7):1028-34. doi: 10.3760/cma.j.issn.0254-6450.2016.07.024. Chinese.


Effect of homocysteine-lowering B vitamin treatment on angiographic progression of coronary artery disease: a Western Norway B Vitamin Intervention Trial (WENBIT) substudy.

Løland KH, Bleie O, Blix AJ, Strand E, Ueland PM, Refsum H, Ebbing M, Nordrehaug JE, Nygård O.

Am J Cardiol. 2010 Jun 1;105(11):1577-84. doi: 10.1016/j.amjcard.2010.01.019.


Effect of homocysteine-lowering therapy on vascular endothelial function and exercise performance in coronary patients with hyperhomocysteinaemia.

Dinckal MH, Aksoy N, Aksoy M, Davutoglu V, Soydinc S, Kirilmaz A, Dinckal N, Akdemir I.

Acta Cardiol. 2003 Oct;58(5):389-96.


Effect of homocysteine-lowering treatment with folic Acid and B vitamins on risk of type 2 diabetes in women: a randomized, controlled trial.

Song Y, Cook NR, Albert CM, Van Denburgh M, Manson JE.

Diabetes. 2009 Aug;58(8):1921-8. doi: 10.2337/db09-0087.


Homocysteine lowering with folic acid and B vitamins in people with chronic kidney disease--results of the renal Hope-2 study.

Mann JF, Sheridan P, McQueen MJ, Held C, Arnold JM, Fodor G, Yusuf S, Lonn EM; HOPE-2 investigators..

Nephrol Dial Transplant. 2008 Feb;23(2):645-53.


Folic acid and vitamin B12 are more effective than vitamin B6 in lowering fasting plasma homocysteine concentration in patients with coronary artery disease.

Lee BJ, Huang MC, Chung LJ, Cheng CH, Lin KL, Su KH, Huang YC.

Eur J Clin Nutr. 2004 Mar;58(3):481-7.


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