Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 100

1.

Identification and characterization of the interaction between tuberin and 14-3-3zeta.

Nellist M, Goedbloed MA, de Winter C, Verhaaf B, Jankie A, Reuser AJ, van den Ouweland AM, van der Sluijs P, Halley DJ.

J Biol Chem. 2002 Oct 18;277(42):39417-24. Epub 2002 Aug 9.

PMID:
12176984
2.

TSC2 missense mutations inhibit tuberin phosphorylation and prevent formation of the tuberin-hamartin complex.

Nellist M, Verhaaf B, Goedbloed MA, Reuser AJ, van den Ouweland AM, Halley DJ.

Hum Mol Genet. 2001 Dec 1;10(25):2889-98.

PMID:
11741832
3.

Pathological mutations in TSC1 and TSC2 disrupt the interaction between hamartin and tuberin.

Hodges AK, Li S, Maynard J, Parry L, Braverman R, Cheadle JP, DeClue JE, Sampson JR.

Hum Mol Genet. 2001 Dec 1;10(25):2899-905.

PMID:
11741833
4.

Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products.

van Slegtenhorst M, Nellist M, Nagelkerken B, Cheadle J, Snell R, van den Ouweland A, Reuser A, Sampson J, Halley D, van der Sluijs P.

Hum Mol Genet. 1998 Jun;7(6):1053-7.

PMID:
9580671
5.

Tuberin phosphorylation regulates its interaction with hamartin. Two proteins involved in tuberous sclerosis.

Aicher LD, Campbell JS, Yeung RS.

J Biol Chem. 2001 Jun 15;276(24):21017-21. Epub 2001 Apr 4.

PMID:
11290735
6.

Characterization of the cytosolic tuberin-hamartin complex. Tuberin is a cytosolic chaperone for hamartin.

Nellist M, van Slegtenhorst MA, Goedbloed M, van den Ouweland AM, Halley DJ, van der Sluijs P.

J Biol Chem. 1999 Dec 10;274(50):35647-52.

PMID:
10585443
7.

14-3-3beta binds to and negatively regulates the tuberous sclerosis complex 2 (TSC2) tumor suppressor gene product, tuberin.

Shumway SD, Li Y, Xiong Y.

J Biol Chem. 2003 Jan 24;278(4):2089-92. Epub 2002 Dec 4.

PMID:
12468542
8.

Regulation of tuberous sclerosis complex (TSC) function by 14-3-3 proteins.

Nellist M, Goedbloed MA, Halley DJ.

Biochem Soc Trans. 2003 Jun;31(Pt 3):587-91. Review.

PMID:
12773161
9.

Cell cycle-regulated phosphorylation of hamartin, the product of the tuberous sclerosis complex 1 gene, by cyclin-dependent kinase 1/cyclin B.

Astrinidis A, Senapedis W, Coleman TR, Henske EP.

J Biol Chem. 2003 Dec 19;278(51):51372-9. Epub 2003 Oct 9.

PMID:
14551205
10.

Tuberin binds p27 and negatively regulates its interaction with the SCF component Skp2.

Rosner M, Hengstschläger M.

J Biol Chem. 2004 Nov 19;279(47):48707-15. Epub 2004 Sep 8.

PMID:
15355997
11.
12.

The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination.

Benvenuto G, Li S, Brown SJ, Braverman R, Vass WC, Cheadle JP, Halley DJ, Sampson JR, Wienecke R, DeClue JE.

Oncogene. 2000 Dec 14;19(54):6306-16.

PMID:
11175345
13.

The TSC1 tumor suppressor hamartin interacts with neurofilament-L and possibly functions as a novel integrator of the neuronal cytoskeleton.

Haddad LA, Smith N, Bowser M, Niida Y, Murthy V, Gonzalez-Agosti C, Ramesh V.

J Biol Chem. 2002 Nov 15;277(46):44180-6. Epub 2002 Sep 10.

PMID:
12226091
14.

The tuberin-hamartin complex negatively regulates beta-catenin signaling activity.

Mak BC, Takemaru K, Kenerson HL, Moon RT, Yeung RS.

J Biol Chem. 2003 Feb 21;278(8):5947-51. Epub 2003 Jan 2.

PMID:
12511557
15.

Differential localization of hamartin and tuberin and increased S6 phosphorylation in a tuber.

Jansen FE, Notenboom RG, Nellist M, Goedbloed MA, Halley DJ, de Graan PN, van Nieuwenhuizen O.

Neurology. 2004 Oct 12;63(7):1293-5.

PMID:
15477556
16.

Distinct effects of single amino-acid changes to tuberin on the function of the tuberin-hamartin complex.

Nellist M, Sancak O, Goedbloed MA, Rohe C, van Netten D, Mayer K, Tucker-Williams A, van den Ouweland AM, Halley DJ.

Eur J Hum Genet. 2005 Jan;13(1):59-68.

PMID:
15483652
17.

Hamartin and tuberin interaction with the G2/M cyclin-dependent kinase CDK1 and its regulatory cyclins A and B.

Catania MG, Mischel PS, Vinters HV.

J Neuropathol Exp Neurol. 2001 Jul;60(7):711-23.

PMID:
11444800
18.

Analysis of TSC2 stop codon variants found in tuberous sclerosis patients.

Goedbloed MA, Nellist M, Verhaaf B, Reuser AJ, Lindhout D, Sunde L, Verhoef S, Halley DJ, van den Ouweland AM.

Eur J Hum Genet. 2001 Nov;9(11):823-8.

PMID:
11781698
19.

Tuberous sclerosis genes regulate cellular 14-3-3 protein levels.

Hengstschläger M, Rosner M, Fountoulakis M, Lubec G.

Biochem Biophys Res Commun. 2003 Dec 19;312(3):676-83.

PMID:
14680818
20.

The TSC1 gene product, hamartin, negatively regulates cell proliferation.

Miloloza A, Rosner M, Nellist M, Halley D, Bernaschek G, Hengstschläger M.

Hum Mol Genet. 2000 Jul 22;9(12):1721-7.

PMID:
10915759

Supplemental Content

Support Center