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Items: 1 to 20 of 109

1.

Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation.

Rodriguez-Puebla ML, Miliani de Marval PL, LaCava M, Moons DS, Kiyokawa H, Conti CJ.

Am J Pathol. 2002 Aug;161(2):405-11.

2.

Lack of cyclin-dependent kinase 4 inhibits c-myc tumorigenic activities in epithelial tissues.

Miliani de Marval PL, Macias E, Rounbehler R, Sicinski P, Kiyokawa H, Johnson DG, Conti CJ, Rodriguez-Puebla ML.

Mol Cell Biol. 2004 Sep;24(17):7538-47.

3.

Unexpected reduction of skin tumorigenesis on expression of cyclin-dependent kinase 6 in mouse epidermis.

Wang X, Sistrunk C, Rodriguez-Puebla ML.

Am J Pathol. 2011 Jan;178(1):345-54. doi: 10.1016/j.ajpath.2010.11.032.

5.
6.

Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis.

Macias E, Kim Y, Miliani de Marval PL, Klein-Szanto A, Rodriguez-Puebla ML.

Cancer Res. 2007 Oct 15;67(20):9713-20.

7.

Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

Lukas J, Bartkova J, Rohde M, Strauss M, Bartek J.

Mol Cell Biol. 1995 May;15(5):2600-11.

8.

Cooperation between Cdk4 and p27kip1 in tumor development: a preclinical model to evaluate cell cycle inhibitors with therapeutic activity.

Sotillo R, Renner O, Dubus P, Ruiz-Cabello J, Martín-Caballero J, Barbacid M, Carnero A, Malumbres M.

Cancer Res. 2005 May 1;65(9):3846-52.

9.

The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis.

Bartkova J, Lukas J, Guldberg P, Alsner J, Kirkin AF, Zeuthen J, Bartek J.

Cancer Res. 1996 Dec 1;56(23):5475-83.

10.
11.

Chemical transformation of mouse liver cells results in altered cyclin D-CDK protein complexes.

Gonzales AJ, Goldsworthy TL, Fox TR.

Carcinogenesis. 1998 Jun;19(6):1093-102.

12.

Enhanced malignant tumorigenesis in Cdk4 transgenic mice.

Miliani de Marval PL, Macias E, Conti CJ, Rodriguez-Puebla ML.

Oncogene. 2004 Mar 11;23(10):1863-73.

13.

CDK2 activation in mouse epidermis induces keratinocyte proliferation but does not affect skin tumor development.

Macias E, Miliani de Marval PL, De Siervi A, Conti CJ, Senderowicz AM, Rodriguez-Puebla ML.

Am J Pathol. 2008 Aug;173(2):526-35. doi: 10.2353/ajpath.2008.071124.

14.

Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis.

Tiano HF, Loftin CD, Akunda J, Lee CA, Spalding J, Sessoms A, Dunson DB, Rogan EG, Morham SG, Smart RC, Langenbach R.

Cancer Res. 2002 Jun 15;62(12):3395-401.

15.

ErbB2/Neu-induced, cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells.

Muraoka RS, Lenferink AE, Law B, Hamilton E, Brantley DM, Roebuck LR, Arteaga CL.

Mol Cell Biol. 2002 Apr;22(7):2204-19.

16.
17.

Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin.

Guo H, Miao H, Gerber L, Singh J, Denning MF, Gilliam AC, Wang B.

Cancer Res. 2006 Jul 15;66(14):7050-8.

19.

Transgenic expression of cyclin-dependent kinase 4 results in epidermal hyperplasia, hypertrophy, and severe dermal fibrosis.

Miliani de Marval PL, Gimenez-Conti IB, LaCava M, Martinez LA, Conti CJ, Rodriguez-Puebla ML.

Am J Pathol. 2001 Jul;159(1):369-79.

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