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Items: 1 to 20 of 1198

1.

Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved.

Pandini G, Frasca F, Mineo R, Sciacca L, Vigneri R, Belfiore A.

J Biol Chem. 2002 Oct 18;277(42):39684-95. Epub 2002 Jul 22.

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Differences in signaling properties of the cytoplasmic domains of the insulin receptor and insulin-like growth factor receptor in 3T3-L1 adipocytes.

Ursø B, Cope DL, Kalloo-Hosein HE, Hayward AC, Whitehead JP, O'Rahilly S, Siddle K.

J Biol Chem. 1999 Oct 22;274(43):30864-73.

4.

Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.

Denley A, Carroll JM, Brierley GV, Cosgrove L, Wallace J, Forbes B, Roberts CT Jr.

Mol Cell Biol. 2007 May;27(10):3569-77. Epub 2007 Feb 26. Erratum in: Mol Cell Biol. 2007 Sep;27(17):6264.

5.

Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.

Lingohr MK, Dickson LM, McCuaig JF, Hugl SR, Twardzik DR, Rhodes CJ.

Diabetes. 2002 Apr;51(4):966-76.

7.

Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: evidence for a second mechanism of IGF-I signaling.

Pandini G, Vigneri R, Costantino A, Frasca F, Ippolito A, Fujita-Yamaguchi Y, Siddle K, Goldfine ID, Belfiore A.

Clin Cancer Res. 1999 Jul;5(7):1935-44.

8.

Characterisation of receptors for IGF-I and insulin; evidence for hybrid insulin/IGF-I receptor in human coronary artery endothelial cells.

Chisalita SI, Nitert MD, Arnqvist HJ.

Growth Horm IGF Res. 2006 Aug;16(4):258-66. Epub 2006 Aug 17.

PMID:
16914341
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Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant.

Slaaby R, Schäffer L, Lautrup-Larsen I, Andersen AS, Shaw AC, Mathiasen IS, Brandt J.

J Biol Chem. 2006 Sep 8;281(36):25869-74. Epub 2006 Jul 10.

12.

IRS-1 tyrosine phosphorylation reflects insulin-induced metabolic and mitogenic responses in 3T3-L1 pre-adipocytes.

Telting D, van der Zon GC, Dorrestijn J, Maassen JA.

Arch Physiol Biochem. 2001 Feb;109(1):52-62.

PMID:
11471071
13.

Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

Frasca F, Pandini G, Scalia P, Sciacca L, Mineo R, Costantino A, Goldfine ID, Belfiore A, Vigneri R.

Mol Cell Biol. 1999 May;19(5):3278-88.

14.

A PDZ domain protein interacts with the C-terminal tail of the insulin-like growth factor-1 receptor but not with the insulin receptor.

Ligensa T, Krauss S, Demuth D, Schumacher R, Camonis J, Jaques G, Weidner KM.

J Biol Chem. 2001 Sep 7;276(36):33419-27. Epub 2001 Jul 9.

15.

Differential expression of IGF-I and insulin receptor isoforms in HPV positive and negative human cervical cancer cell lines.

Serrano ML, Sánchez-Gómez M, Bravo MM, Yakar S, LeRoith D.

Horm Metab Res. 2008 Oct;40(10):661-7. doi: 10.1055/s-0028-1082080. Epub 2008 Aug 18.

PMID:
18711691
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Differential gene expression induced by insulin and insulin-like growth factor-II through the insulin receptor isoform A.

Pandini G, Medico E, Conte E, Sciacca L, Vigneri R, Belfiore A.

J Biol Chem. 2003 Oct 24;278(43):42178-89. Epub 2003 Jul 24.

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Differential signaling activation by insulin and insulin-like growth factors I and II upon binding to insulin receptor isoform A.

Sacco A, Morcavallo A, Pandini G, Vigneri R, Belfiore A.

Endocrinology. 2009 Aug;150(8):3594-602. doi: 10.1210/en.2009-0377. Epub 2009 May 14.

PMID:
19443570

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