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Items: 1 to 20 of 259

1.

MSI in endometrial carcinoma: absence of MLH1 promoter methylation is associated with increased familial risk for cancers.

Whelan AJ, Babb S, Mutch DG, Rader J, Herzog TJ, Todd C, Ivanovich JL, Goodfellow PJ.

Int J Cancer. 2002 Jun 10;99(5):697-704.

2.

MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers.

Simpkins SB, Bocker T, Swisher EM, Mutch DG, Gersell DJ, Kovatich AJ, Palazzo JP, Fishel R, Goodfellow PJ.

Hum Mol Genet. 1999 Apr;8(4):661-6.

PMID:
10072435
3.

MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas.

Esteller M, Levine R, Baylin SB, Ellenson LH, Herman JG.

Oncogene. 1998 Nov 5;17(18):2413-7.

4.

Extended microsatellite analysis in microsatellite stable, MSH2 and MLH1 mutation-negative HNPCC patients: genetic reclassification and correlation with clinical features.

Schiemann U, Müller-Koch Y, Gross M, Daum J, Lohse P, Baretton G, Muders M, Mussack T, Kopp R, Holinski-Feder E.

Digestion. 2004;69(3):166-76. Epub 2004 Apr 28.

PMID:
15118395
5.
6.

The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers.

Lawes DA, Pearson T, Sengupta S, Boulos PB.

Br J Cancer. 2005 Aug 22;93(4):472-7.

7.

Microsatellite instability, MLH1 promoter methylation, and loss of mismatch repair in endometrial cancer and concomitant atypical hyperplasia.

Horowitz N, Pinto K, Mutch DG, Herzog TJ, Rader JS, Gibb R, Bocker-Edmonston T, Goodfellow PJ.

Gynecol Oncol. 2002 Jul;86(1):62-8.

PMID:
12079302
8.

Distinction of hereditary nonpolyposis colorectal cancer and sporadic microsatellite-unstable colorectal cancer through quantification of MLH1 methylation by real-time PCR.

Bettstetter M, Dechant S, Ruemmele P, Grabowski M, Keller G, Holinski-Feder E, Hartmann A, Hofstaedter F, Dietmaier W.

Clin Cancer Res. 2007 Jun 1;13(11):3221-8.

9.

Frequent loss of hMLH1 by promoter hypermethylation leads to microsatellite instability in adenomatous polyps of patients with a single first-degree member affected by colon cancer.

Ricciardiello L, Goel A, Mantovani V, Fiorini T, Fossi S, Chang DK, Lunedei V, Pozzato P, Zagari RM, De Luca L, Fuccio L, Martinelli GN, Roda E, Boland CR, Bazzoli F.

Cancer Res. 2003 Feb 15;63(4):787-92.

10.

Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis.

Young J, Simms LA, Biden KG, Wynter C, Whitehall V, Karamatic R, George J, Goldblatt J, Walpole I, Robin SA, Borten MM, Stitz R, Searle J, McKeone D, Fraser L, Purdie DR, Podger K, Price R, Buttenshaw R, Walsh MD, Barker M, Leggett BA, Jass JR.

Am J Pathol. 2001 Dec;159(6):2107-16.

11.

Methylation of hMLH1 in a population-based series of endometrial carcinomas.

Salvesen HB, MacDonald N, Ryan A, Iversen OE, Jacobs IJ, Akslen LA, Das S.

Clin Cancer Res. 2000 Sep;6(9):3607-13.

12.

Genetic and epigenetic modification of MLH1 accounts for a major share of microsatellite-unstable colorectal cancers.

Kuismanen SA, Holmberg MT, Salovaara R, de la Chapelle A, Peltomäki P.

Am J Pathol. 2000 May;156(5):1773-9.

13.

[The first molecular analysis of a Hungarian HNPCC family: a novel MSH2 germline mutation].

Czakó L, Tiszlavicz L, Takács R, Baradnay G, Lonovics J, Cserni G, Závodná K, Bartosova Z.

Orv Hetil. 2005 May 15;146(20):1009-16. Hungarian.

PMID:
15945244
14.

Mismatch repair gene defects contribute to the genetic basis of double primary cancers of the colorectum and endometrium.

Millar AL, Pal T, Madlensky L, Sherman C, Temple L, Mitri A, Cheng H, Marcus V, Gallinger S, Redston M, Bapat B, Narod S.

Hum Mol Genet. 1999 May;8(5):823-9.

PMID:
10196371
15.

Toward new strategies to select young endometrial cancer patients for mismatch repair gene mutation analysis.

Berends MJ, Wu Y, Sijmons RH, van der Sluis T, Ek WB, Ligtenberg MJ, Arts NJ, ten Hoor KA, Kleibeuker JH, de Vries EG, Mourits MJ, Hollema H, Buys CH, Hofstra RM, van der Zee AG.

J Clin Oncol. 2003 Dec 1;21(23):4364-70.

PMID:
14645426
16.

Microsatellite instability and expression of mismatch repair genes in sporadic endometrial cancer coexisting with colorectal or breast cancer.

Takano K, Ichikawa Y, Ueno E, Ohwada M, Suzuki M, Tsunoda H, Miwa M, Uchida K, Yoshikawa H.

Oncol Rep. 2005 Jan;13(1):11-6.

PMID:
15583795
17.

Microsatellite instability and hMLH1/hMSH2 expression in young endometrial carcinoma patients: associations with family history and histopathology.

Parc YR, Halling KC, Burgart LJ, McDonnell SK, Schaid DJ, Thibodeau SN, Halling AC.

Int J Cancer. 2000 Apr 1;86(1):60-6.

18.

Microsatellite instability and expression of MLH1 and MSH2 in normal and malignant endometrial and ovarian epithelium in hereditary nonpolyposis colorectal cancer family members.

Ichikawa Y, Lemon SJ, Wang S, Franklin B, Watson P, Knezetic JA, Bewtra C, Lynch HT.

Cancer Genet Cytogenet. 1999 Jul 1;112(1):2-8.

PMID:
10432927
19.

BRAF mutations in colorectal carcinoma suggest two entities of microsatellite-unstable tumors.

Lubomierski N, Plotz G, Wormek M, Engels K, Kriener S, Trojan J, Jungling B, Zeuzem S, Raedle J.

Cancer. 2005 Sep 1;104(5):952-61.

20.

MLH1 and MSH2 protein expression as a pre-screening marker in hereditary and non-hereditary endometrial hyperplasia and cancer.

Berends MJ, Hollema H, Wu Y, van Der Sluis T, Mensink RG, ten Hoor KA, Sijmons RH, de Vries EG, Pras E, Mourits MJ, Hofstra RM, Buys CH, Kleibeuker JH, van Der Zee AG.

Int J Cancer. 2001 May 1;92(3):398-403.

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