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Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype.

Goudreau G, Petrou P, Reneker LW, Graw J, Löster J, Gruss P.

Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8719-24. Epub 2002 Jun 18.


Pax6-dependence of Six3, Eya1 and Dach1 expression during lens and nasal placode induction.

Purcell P, Oliver G, Mardon G, Donner AL, Maas RL.

Gene Expr Patterns. 2005 Dec;6(1):110-8. Epub 2005 Jul 18.


Six3 activation of Pax6 expression is essential for mammalian lens induction and specification.

Liu W, Lagutin OV, Mende M, Streit A, Oliver G.

EMBO J. 2006 Nov 15;25(22):5383-95. Epub 2006 Oct 26.


Pax6- and Six3-mediated induction of lens cell fate in mouse and human ES cells.

Anchan RM, Lachke SA, Gerami-Naini B, Lindsey J, Ng N, Naber C, Nickerson M, Cavallesco R, Rowan S, Eaton JL, Xi Q, Maas RL.

PLoS One. 2014 Dec 17;9(12):e115106. doi: 10.1371/journal.pone.0115106. eCollection 2014.


Dosage requirement and allelic expression of PAX6 during lens placode formation.

van Raamsdonk CD, Tilghman SM.

Development. 2000 Dec;127(24):5439-48.


Six3 promotes the formation of ectopic optic vesicle-like structures in mouse embryos.

Lagutin O, Zhu CC, Furuta Y, Rowitch DH, McMahon AP, Oliver G.

Dev Dyn. 2001 Jul;221(3):342-9.


Identification of genes downstream of Pax6 in the mouse lens using cDNA microarrays.

Chauhan BK, Reed NA, Zhang W, Duncan MK, Kilimann MW, Cvekl A.

J Biol Chem. 2002 Mar 29;277(13):11539-48. Epub 2002 Jan 14.


Retinal expression of zebrafish six3.1 and its regulation by Pax6.

Wargelius A, Seo HC, Austbø L, Fjose A.

Biochem Biophys Res Commun. 2003 Sep 19;309(2):475-81.


Distinct roles of SOX2, Pax6 and Maf transcription factors in the regulation of lens-specific delta1-crystallin enhancer.

Muta M, Kamachi Y, Yoshimoto A, Higashi Y, Kondoh H.

Genes Cells. 2002 Aug;7(8):791-805.


Regulation of gene expression by Pax6 in ocular cells: a case of tissue-preferred expression of crystallins in lens.

Cvekl A, Yang Y, Chauhan BK, Cveklova K.

Int J Dev Biol. 2004;48(8-9):829-44. Review.


Identification of differentially expressed genes in mouse Pax6 heterozygous lenses.

Chauhan BK, Zhang W, Cveklova K, Kantorow M, Cvekl A.

Invest Ophthalmol Vis Sci. 2002 Jun;43(6):1884-90.


Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis.

Zhang X, Friedman A, Heaney S, Purcell P, Maas RL.

Genes Dev. 2002 Aug 15;16(16):2097-107.


Ectopic lens induction in fish in response to the murine homeobox gene Six3.

Oliver G, Loosli F, Köster R, Wittbrodt J, Gruss P.

Mech Dev. 1996 Dec;60(2):233-9.


Identification of pax6-dependent gene regulatory networks in the mouse lens.

Wolf LV, Yang Y, Wang J, Xie Q, Braunger B, Tamm ER, Zavadil J, Cvekl A.

PLoS One. 2009;4(1):e4159. doi: 10.1371/journal.pone.0004159. Epub 2009 Jan 9. Erratum in: PLoS ONE. 2009;4(3). doi: 10.1371/annotation/71d78295-dc0f-4e78-9c99-45b730952d9b.


Ectopic Pax6 expression disturbs lens fiber cell differentiation.

Duncan MK, Xie L, David LL, Robinson ML, Taube JR, Cui W, Reneker LW.

Invest Ophthalmol Vis Sci. 2004 Oct;45(10):3589-98.


L-Maf, a downstream target of Pax6, is essential for chick lens development.

Reza HM, Ogino H, Yasuda K.

Mech Dev. 2002 Aug;116(1-2):61-73.


Penetrance of eye defects in mice heterozygous for mutation of Gli3 is enhanced by heterozygous mutation of Pax6.

Zaki PA, Collinson JM, Toraiwa J, Simpson TI, Price DJ, Quinn JC.

BMC Dev Biol. 2006 Oct 9;6:46.

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