Similar articles for PMID: 12036925

Year	Number of Results
1991	2
1994	1
1995	3
1997	2
1998	1
1999	5
2000	3
2001	13
2002	15
2003	23
2004	20
2005	19
2006	7
2007	6
2008	3
2009	5
2010	5
2011	5
2012	12
2013	7
2014	8
2015	14
2016	7
2017	8
2018	3
2019	7
2020	6
2021	6
2022	7
2024	0

1

Degradation of HER2 by ansamycins induces growth arrest and apoptosis in cells with HER2 overexpression via a HER3, phosphatidylinositol 3'-kinase-AKT-dependent pathway.

Münster PN, Marchion DC, Basso AD, Rosen N. Münster PN, et al. Cancer Res. 2002 Jun 1;62(11):3132-7. Cancer Res. 2002. PMID: 12036925

2

Ansamycin antibiotics inhibit Akt activation and cyclin D expression in breast cancer cells that overexpress HER2.

Basso AD, Solit DB, Munster PN, Rosen N. Basso AD, et al. Oncogene. 2002 Feb 14;21(8):1159-66. doi: 10.1038/sj.onc.1205184. Oncogene. 2002. PMID: 11850835 Free PMC article.

3

Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to Taxol.

Solit DB, Basso AD, Olshen AB, Scher HI, Rosen N. Solit DB, et al. Cancer Res. 2003 May 1;63(9):2139-44. Cancer Res. 2003. PMID: 12727831

4

HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells.

Knuefermann C, Lu Y, Liu B, Jin W, Liang K, Wu L, Schmidt M, Mills GB, Mendelsohn J, Fan Z. Knuefermann C, et al. Oncogene. 2003 May 22;22(21):3205-12. doi: 10.1038/sj.onc.1206394. Oncogene. 2003. PMID: 12761490

5

Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.

Georgakis GV, Li Y, Rassidakis GZ, Martinez-Valdez H, Medeiros LJ, Younes A. Georgakis GV, et al. Clin Cancer Res. 2006 Jan 15;12(2):584-90. doi: 10.1158/1078-0432.CCR-05-1194. Clin Cancer Res. 2006. PMID: 16428504

6

Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells.

Münster PN, Srethapakdi M, Moasser MM, Rosen N. Münster PN, et al. Cancer Res. 2001 Apr 1;61(7):2945-52. Cancer Res. 2001. PMID: 11306472

7

Cotreatment with suberanoylanilide hydroxamic acid and 17-allylamino 17-demethoxygeldanamycin synergistically induces apoptosis in Bcr-Abl+ Cells sensitive and resistant to STI571 (imatinib mesylate) in association with down-regulation of Bcr-Abl, abrogation of signal transducer and activator of transcription 5 activity, and Bax conformational change.

Rahmani M, Reese E, Dai Y, Bauer C, Kramer LB, Huang M, Jove R, Dent P, Grant S. Rahmani M, et al. Mol Pharmacol. 2005 Apr;67(4):1166-76. doi: 10.1124/mol.104.007831. Epub 2004 Dec 29. Mol Pharmacol. 2005. PMID: 15625278

8

Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity.

deGraffenried LA, Friedrichs WE, Russell DH, Donzis EJ, Middleton AK, Silva JM, Roth RA, Hidalgo M. deGraffenried LA, et al. Clin Cancer Res. 2004 Dec 1;10(23):8059-67. doi: 10.1158/1078-0432.CCR-04-0035. Clin Cancer Res. 2004. PMID: 15585641

9

17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts.

Solit DB, Zheng FF, Drobnjak M, Münster PN, Higgins B, Verbel D, Heller G, Tong W, Cordon-Cardo C, Agus DB, Scher HI, Rosen N. Solit DB, et al. Clin Cancer Res. 2002 May;8(5):986-93. Clin Cancer Res. 2002. PMID: 12006510

10

Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells.

Asanuma H, Torigoe T, Kamiguchi K, Hirohashi Y, Ohmura T, Hirata K, Sato M, Sato N. Asanuma H, et al. Cancer Res. 2005 Dec 1;65(23):11018-25. doi: 10.1158/0008-5472.CAN-05-0491. Cancer Res. 2005. PMID: 16322251

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