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Items: 1 to 20 of 347

1.

A recombinant CD7-specific single-chain immunotoxin is a potent inducer of apoptosis in acute leukemic T cells.

Peipp M, Küpers H, Saul D, Schlierf B, Greil J, Zunino SJ, Gramatzki M, Fey GH.

Cancer Res. 2002 May 15;62(10):2848-55.

2.

Target cell-restricted apoptosis induction of acute leukemic T cells by a recombinant tumor necrosis factor-related apoptosis-inducing ligand fusion protein with specificity for human CD7.

Bremer E, Samplonius DF, Peipp M, van Genne L, Kroesen BJ, Fey GH, Gramatzki M, de Leij LF, Helfrich W.

Cancer Res. 2005 Apr 15;65(8):3380-8.

3.

Recombinant CD64-specific single chain immunotoxin exhibits specific cytotoxicity against acute myeloid leukemia cells.

Tur MK, Huhn M, Thepen T, Stöcker M, Krohn R, Vogel S, Jost E, Osieka R, van de Winkel JG, Fischer R, Finnern R, Barth S.

Cancer Res. 2003 Dec 1;63(23):8414-9. Erratum in: Cancer Res. 2004 May 15;;64(14):3725.

4.

A CD33-specific single-chain immunotoxin mediates potent apoptosis of cultured human myeloid leukaemia cells.

Schwemmlein M, Peipp M, Barbin K, Saul D, Stockmeyer B, Repp R, Birkmann J, Oduncu F, Emmerich B, Fey GH.

Br J Haematol. 2006 Apr;133(2):141-51.

PMID:
16611304
5.

Influence of relative binding affinity on efficacy in a panel of anti-CD3 scFv immunotoxins.

Hexham JM, Dudas D, Hugo R, Thompson J, King V, Dowling C, Neville DM Jr, Digan ME, Lake P.

Mol Immunol. 2001 Sep;38(5):397-408.

PMID:
11684296
6.

The recombinant immunotoxin anti-Tac(Fv)-Pseudomonas exotoxin 40 is cytotoxic toward peripheral blood malignant cells from patients with adult T-cell leukemia.

Kreitman RJ, Chaudhary VK, Waldmann T, Willingham MC, FitzGerald DJ, Pastan I.

Proc Natl Acad Sci U S A. 1990 Nov;87(21):8291-5.

8.

Cytotoxicity of recombinant Fab and Fv immunotoxins on adult T-cell leukemia lymph node and blood cells in the presence of soluble interleukin-2 receptor.

Saito T, Kreitman RJ, Hanada S, Makino T, Utsunomiya A, Sumizawa T, Arima T, Chang CN, Hudson D, Pastan I, et al.

Cancer Res. 1994 Feb 15;54(4):1059-64.

PMID:
8313362
9.

Activity of a single-chain immunotoxin that selectively kills lymphoma and other B-lineage cells expressing the CD40 antigen.

Francisco JA, Gilliland LK, Stebbins MR, Norris NA, Ledbetter JA, Siegall CB.

Cancer Res. 1995 Jul 15;55(14):3099-104.

10.

Target-specific cytotoxic activity of recombinant immunotoxin scFv(MUC1)-ETA on breast carcinoma cells and primary breast tumors.

Singh R, Samant U, Hyland S, Chaudhari PR, Wels WS, Bandyopadhyay D.

Mol Cancer Ther. 2007 Feb;6(2):562-9.

11.

CD7-restricted activation of Fas-mediated apoptosis: a novel therapeutic approach for acute T-cell leukemia.

Bremer E, ten Cate B, Samplonius DF, de Leij LF, Helfrich W.

Blood. 2006 Apr 1;107(7):2863-70. Epub 2005 Dec 6.

12.

Role of caspases in immunotoxin-induced apoptosis of cancer cells.

Keppler-Hafkemeyer A, Brinkmann U, Pastan I.

Biochemistry. 1998 Dec 1;37(48):16934-42.

PMID:
9836586
13.

A recombinant immunotoxin derived from a humanized epithelial cell adhesion molecule-specific single-chain antibody fragment has potent and selective antitumor activity.

Di Paolo C, Willuda J, Kubetzko S, Lauffer I, Tschudi D, Waibel R, Plückthun A, Stahel RA, Zangemeister-Wittke U.

Clin Cancer Res. 2003 Jul;9(7):2837-48. Erratum in: Clin Cancer Res. 2004 Apr 1;10(7):2579.

14.

Novel conjugates of single-chain Fv antibody fragments specific for stem cell antigen CD123 mediate potent death of acute myeloid leukaemia cells.

Stein C, Kellner C, Kügler M, Reiff N, Mentz K, Schwenkert M, Stockmeyer B, Mackensen A, Fey GH.

Br J Haematol. 2010 Mar;148(6):879-89. doi: 10.1111/j.1365-2141.2009.08033.x. Epub 2010 Jan 8.

PMID:
20064159
15.

Construction and characterization of human CD7-specific single-chain Fv immunotoxins.

Pauza ME, Doumbia SO, Pennell CA.

J Immunol. 1997 Apr 1;158(7):3259-69.

PMID:
9120282
16.

Novel anti-CD30 recombinant immunotoxins containing disulfide-stabilized Fv fragments.

Nagata S, Onda M, Numata Y, Santora K, Beers R, Kreitman RJ, Pastan I.

Clin Cancer Res. 2002 Jul;8(7):2345-55.

17.

Evaluation of cell surface antigens as potential targets for recombinant tumor toxins.

Wick B, Groner B.

Cancer Lett. 1997 Oct 14;118(2):161-72.

PMID:
9459206
18.

An anti-GD2 single chain Fv selected by phage display and fused to Pseudomonas exotoxin A develops specific cytotoxic activity against neuroblastoma derived cell lines.

Tur MK, Sasse S, Stöcker M, Djabelkhir K, Huhn M, Matthey B, Gottstein C, Pfitzner T, Engert A, Barth S.

Int J Mol Med. 2001 Nov;8(5):579-84.

PMID:
11605031
19.

Recombinant single-chain immunotoxins against T and B cell leukemias.

Kreitman RJ, Pastan I.

Leuk Lymphoma. 1994 Mar;13(1-2):1-10. Review.

PMID:
8025511

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