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Items: 1 to 20 of 106

1.

A small molecule ubiquitination inhibitor blocks NF-kappa B-dependent cytokine expression in cells and rats.

Swinney DC, Xu YZ, Scarafia LE, Lee I, Mak AY, Gan QF, Ramesha CS, Mulkins MA, Dunn J, So OY, Biegel T, Dinh M, Volkel P, Barnett J, Dalrymple SA, Lee S, Huber M.

J Biol Chem. 2002 Jun 28;277(26):23573-81.

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Identification of lysine residues required for signal-induced ubiquitination and degradation of I kappa B-alpha in vivo.

Rodriguez MS, Wright J, Thompson J, Thomas D, Baleux F, Virelizier JL, Hay RT, Arenzana-Seisdedos F.

Oncogene. 1996 Jun 6;12(11):2425-35.

PMID:
8649784
5.

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity.

Karin M, Ben-Neriah Y.

Annu Rev Immunol. 2000;18:621-63. Review.

PMID:
10837071
8.

NO inhibits cytokine-induced iNOS expression and NF-kappaB activation by interfering with phosphorylation and degradation of IkappaB-alpha.

Katsuyama K, Shichiri M, Marumo F, Hirata Y.

Arterioscler Thromb Vasc Biol. 1998 Nov;18(11):1796-802.

11.

Effect of proteasome inhibitors on monocytic IkappaB-alpha and -beta depletion, NF-kappaB activation, and cytokine production.

Haas M, Page S, Page M, Neumann FJ, Marx N, Adam M, Ziegler-Heitbrock HW, Neumeier D, Brand K.

J Leukoc Biol. 1998 Mar;63(3):395-404.

PMID:
9500529
12.

Interleukin-10 stabilizes inhibitory kappaB-alpha in human monocytes.

Shames BD, Selzman CH, Meldrum DR, Pulido EJ, Barton HA, Meng X, Harken AH, McIntyre RC Jr.

Shock. 1998 Dec;10(6):389-94.

PMID:
9872676
13.

Effects of acetaldehyde and TNF alpha on the inhibitory kappa B-alpha protein and nuclear factor kappa B activation in hepatic stellate cells.

Novitskiy G, Ravi R, Potter JJ, Rennie-Tankersley L, Wang L, Mezey E.

Alcohol Alcohol. 2005 Mar-Apr;40(2):96-101.

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Differential inhibitory actions by glucocorticoid and aspirin on cytokine-induced nitric oxide production in vascular smooth muscle cells.

Katsuyama K, Shichiri M, Kato H, Imai T, Marumo F, Hirata Y.

Endocrinology. 1999 May;140(5):2183-90.

PMID:
10218970
20.

A selective small molecule IkappaB Kinase beta inhibitor blocks nuclear factor kappaB-mediated inflammatory responses in human fibroblast-like synoviocytes, chondrocytes, and mast cells.

Wen D, Nong Y, Morgan JG, Gangurde P, Bielecki A, Dasilva J, Keaveney M, Cheng H, Fraser C, Schopf L, Hepperle M, Harriman G, Jaffee BD, Ocain TD, Xu Y.

J Pharmacol Exp Ther. 2006 Jun;317(3):989-1001.

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