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c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.

Iijima Y, Laser M, Shiraishi H, Willey CD, Sundaravadivel B, Xu L, McDermott PJ, Kuppuswamy D.

J Biol Chem. 2002 Jun 21;277(25):23065-75. Epub 2002 Apr 8.


Cross-talk between the ERK and p70 S6 kinase (S6K) signaling pathways. MEK-dependent activation of S6K2 in cardiomyocytes.

Wang L, Gout I, Proud CG.

J Biol Chem. 2001 Aug 31;276(35):32670-7. Epub 2001 Jun 28.


Thrombin-stimulated cell proliferation mediated through activation of Ras/Raf/MEK/MAPK pathway in canine cultured tracheal smooth muscle cells.

Lin CC, Shyr MH, Chien CS, Wang CC, Chiu CT, Hsiao LD, Yang CM.

Cell Signal. 2002 Mar;14(3):265-75.


Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.

Ehses JA, Pelech SL, Pederson RA, McIntosh CH.

J Biol Chem. 2002 Oct 4;277(40):37088-97. Epub 2002 Jul 22.


Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway.

Subramaniam S, Shahani N, Strelau J, Laliberté C, Brandt R, Kaplan D, Unsicker K.

J Neurosci. 2005 Mar 16;25(11):2838-52.


Protein kinase A and protein kinase C synergistically activate the Raf-1 kinase/mitogen-activated protein kinase cascade in neonatal rat cardiomyocytes.

Yamazaki T, Komuro I, Zou Y, Kudoh S, Mizuno T, Hiroi Y, Shiojima I, Takano H, Kinugawa Ki, Kohmoto O, Takahashi T, Yazaki Y.

J Mol Cell Cardiol. 1997 Sep;29(9):2491-501.


The PI3K/Akt and mTOR/P70S6K signaling pathways in human uveal melanoma cells: interaction with B-Raf/ERK.

Babchia N, Calipel A, Mouriaux F, Faussat AM, Mascarelli F.

Invest Ophthalmol Vis Sci. 2010 Jan;51(1):421-9. doi: 10.1167/iovs.09-3974. Epub 2009 Aug 6.


Role of ras-dependent ERK activation in phorbol ester-induced endothelial cell barrier dysfunction.

Verin AD, Liu F, Bogatcheva N, Borbiev T, Hershenson MB, Wang P, Garcia JG.

Am J Physiol Lung Cell Mol Physiol. 2000 Aug;279(2):L360-70.


Neurotensin stimulates protein kinase C-dependent mitogenic signaling in human pancreatic carcinoma cell line PANC-1.

Guha S, Lunn JA, Santiskulvong C, Rozengurt E.

Cancer Res. 2003 May 15;63(10):2379-87.


Constitutively active Galpha16 stimulates STAT3 via a c-Src/JAK- and ERK-dependent mechanism.

Lo RK, Cheung H, Wong YH.

J Biol Chem. 2003 Dec 26;278(52):52154-65. Epub 2003 Oct 9.


Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site.

Saitoh M, Pullen N, Brennan P, Cantrell D, Dennis PB, Thomas G.

J Biol Chem. 2002 May 31;277(22):20104-12. Epub 2002 Mar 25.


Stimulation of the Raf/MEK/ERK cascade is necessary and sufficient for activation and Thr-160 phosphorylation of a nuclear-targeted CDK2.

Lents NH, Keenan SM, Bellone C, Baldassare JJ.

J Biol Chem. 2002 Dec 6;277(49):47469-75. Epub 2002 Sep 30.

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