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Folate intake, serum homocysteine and methylenetetrahydrofolate reductase (MTHFR) C677T genotype are not associated with oral cancer risk in Puerto Rico.

Weinstein SJ, Gridley G, Harty LC, Diehl SR, Brown LM, Winn DM, Bravo-Otero E, Hayes RB.

J Nutr. 2002 Apr;132(4):762-7.


A common mutation in the methylenetetrahydrofolate reductase gene and risk of coronary heart disease: results among U.S. men.

Verhoef P, Rimm EB, Hunter DJ, Chen J, Willett WC, Kelsey K, Stampfer MJ.

J Am Coll Cardiol. 1998 Aug;32(2):353-9.


Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.

Ma J, Stampfer MJ, Giovannucci E, Artigas C, Hunter DJ, Fuchs C, Willett WC, Selhub J, Hennekens CH, Rozen R.

Cancer Res. 1997 Mar 15;57(6):1098-102.


Methylenetetrahydrofolate reductase, diet, and risk of colon cancer.

Slattery ML, Potter JD, Samowitz W, Schaffer D, Leppert M.

Cancer Epidemiol Biomarkers Prev. 1999 Jun;8(6):513-8.


Association of methylenetetrahydrofolate reductase polymorphism C677T and dietary folate with the risk of cervical dysplasia.

Goodman MT, McDuffie K, Hernandez B, Wilkens LR, Bertram CC, Killeen J, Le Marchand L, Selhub J, Murphy S, Donlon TA.

Cancer Epidemiol Biomarkers Prev. 2001 Dec;10(12):1275-80.


Optimization of dietary folate or low-dose folic acid supplements lower homocysteine but do not enhance endothelial function in healthy adults, irrespective of the methylenetetrahydrofolate reductase (C677T) genotype.

Pullin CH, Ashfield-Watt PA, Burr ML, Clark ZE, Lewis MJ, Moat SJ, Newcombe RG, Powers HJ, Whiting JM, McDowell IF.

J Am Coll Cardiol. 2001 Dec;38(7):1799-805.


Polymorphisms of methylene-tetrahydrofolate reductase and risk of lung cancer: a case-control study.

Shen H, Spitz MR, Wang LE, Hong WK, Wei Q.

Cancer Epidemiol Biomarkers Prev. 2001 Apr;10(4):397-401.


Low dietary riboflavin but not folate predicts increased fracture risk in postmenopausal women homozygous for the MTHFR 677 T allele.

Yazdanpanah N, Uitterlinden AG, Zillikens MC, Jhamai M, Rivadeneira F, Hofman A, de Jonge R, Lindemans J, Pols HA, van Meurs JB.

J Bone Miner Res. 2008 Jan;23(1):86-94.


The relation between erythrocyte volume and folate levels is influenced by a common mutation in the methylenetetrahydrofolate reductase (MTHFR) gene (C677T).

Lalouschek W, Aull S, Serles W, Wolfsberger M, Deecke L, Pabinger-Fasching I, Mannhalter C.

J Investig Med. 2000 Jan;48(1):14-20.


Determinants of fasting and post-methionine homocysteine levels in families predisposed to hyperhomocysteinemia and premature vascular disease.

de Jong SC, Stehouwer CD, van den Berg M, Kostense PJ, Alders D, Jakobs C, Pals G, Rauwerda JA.

Arterioscler Thromb Vasc Biol. 1999 May;19(5):1316-24.


Nutritional advice to increase soluble fibre intake does not change plasma folate or homocysteine in men with angina: a randomised controlled trial.

Ashfield-Watt PA, Clark ZE, Breay P, Zotos PC, Cale SB, Burr ML, McDowell IF.

Public Health Nutr. 2002 Feb;5(1):47-53.


Polymorphisms of folate metabolic genes and susceptibility to bladder cancer: a case-control study.

Lin J, Spitz MR, Wang Y, Schabath MB, Gorlov IP, Hernandez LM, Pillow PC, Grossman HB, Wu X.

Carcinogenesis. 2004 Sep;25(9):1639-47. Epub 2004 Apr 29.


Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians.

Ma J, Stampfer MJ, Hennekens CH, Frosst P, Selhub J, Horsford J, Malinow MR, Willett WC, Rozen R.

Circulation. 1996 Nov 15;94(10):2410-6.


Homocysteine, folate, methylene tetrahydrofolate reductase genotype and vascular morbidity in diabetic subjects.

Kaye JM, Stanton KG, McCann VJ, Vasikaran SD, Burke V, Taylor RR, van Bockxmeer FM.

Clin Sci (Lond). 2002 Jun;102(6):631-7.


Risk of colorectal cancer associated with the C677T polymorphism in 5,10-methylenetetrahydrofolate reductase in Portuguese patients depends on the intake of methyl-donor nutrients.

Guerreiro CS, Carmona B, Gonçalves S, Carolino E, Fidalgo P, Brito M, Leitão CN, Cravo M.

Am J Clin Nutr. 2008 Nov;88(5):1413-8.


Smoking, folate and methylenetetrahydrofolate reductase status as interactive determinants of adenomatous and hyperplastic polyps of colorectum.

Ulvik A, Evensen ET, Lien EA, Hoff G, Vollset SE, Majak BM, Ueland PM.

Am J Med Genet. 2001 Jul 1;101(3):246-54.


Folate intake, MTHFR C677T polymorphism, alcohol consumption, and risk for sporadic colorectal adenoma (United States).

Boyapati SM, Bostick RM, McGlynn KA, Fina MF, Roufail WM, Geisinger KR, Hebert JR, Coker A, Wargovich M.

Cancer Causes Control. 2004 Jun;15(5):493-501.


Does the interaction between maternal folate intake and the methylenetetrahydrofolate reductase polymorphisms affect the risk of cleft lip with or without cleft palate?

van Rooij IA, Vermeij-Keers C, Kluijtmans LA, Ocké MC, Zielhuis GA, Goorhuis-Brouwer SM, van der Biezen JJ, Kuijpers-Jagtman AM, Steegers-Theunissen RP.

Am J Epidemiol. 2003 Apr 1;157(7):583-91.


Diets, polymorphisms of methylenetetrahydrofolate reductase, and the susceptibility of colon cancer and rectal cancer.

Jiang Q, Chen K, Ma X, Li Q, Yu W, Shu G, Yao K.

Cancer Detect Prev. 2005;29(2):146-54.


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