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Human immunodeficiency virus (HIV)-specific effector CD8 T cell activity in patients with primary HIV infection.

Alter G, Merchant A, Tsoukas CM, Rouleau D, LeBlanc RP, Côté P, Baril JG, Thomas R, Nguyen VK, Sékaly RP, Routy JP, Bernard NF.

J Infect Dis. 2002 Mar 15;185(6):755-65.


Comparison of HIV-specific CD8 T-cell responses among uninfected individuals exposed to HIV parenterally and mucosally.

Makedonas G, Bruneau J, Alary M, Tsoukas CM, Lowndes CM, Lamothe F, Bernard NF.

AIDS. 2005 Feb 18;19(3):251-9.


HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity.

Lichterfeld M, Yu XG, Cohen D, Addo MM, Malenfant J, Perkins B, Pae E, Johnston MN, Strick D, Allen TM, Rosenberg ES, Korber B, Walker BD, Altfeld M.

AIDS. 2004 Jul 2;18(10):1383-92.


CD8 T-cell responses in early HIV-1 infection are skewed towards high entropy peptides.

Bansal A, Gough E, Sabbaj S, Ritter D, Yusim K, Sfakianos G, Aldrovandi G, Kaslow RA, Wilson CM, Mulligan MJ, Kilby JM, Goepfert PA.

AIDS. 2005 Feb 18;19(3):241-50.


Association between Nef-specific CD8 T-cell responses and disease progression in HIV-1 subtype B infection.

Jiao Y, Li TS, Xie J, Han Y, Qiu ZF, Zuo LY, Mourez T, Wang AX.

Chin Med J (Engl). 2006 Oct 5;119(19):1609-15.


Longitudinal assessment of changes in HIV-specific effector activity in HIV-infected patients starting highly active antiretroviral therapy in primary infection.

Alter G, Hatzakis G, Tsoukas CM, Pelley K, Rouleau D, LeBlanc R, Baril JG, Dion H, Lefebvre E, Thomas R, Côté P, Lapointe N, Routy JP, Sékaly RP, Conway B, Bernard NF.

J Immunol. 2003 Jul 1;171(1):477-88.


CD8+ T cell responses to human immunodeficiency viruses type 2 (HIV-2) and type 1 (HIV-1) gag proteins are distinguishable by magnitude and breadth but not cellular phenotype.

Gillespie GM, Pinheiro S, Sayeid-Al-Jamee M, Alabi A, Kaye S, Sabally S, Sarge-Njie R, Njai H, Joof K, Jaye A, Whittle H, Rowland-Jones S, Dorrell L.

Eur J Immunol. 2005 May;35(5):1445-53.


Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load.

Masemola A, Mashishi T, Khoury G, Mohube P, Mokgotho P, Vardas E, Colvin M, Zijenah L, Katzenstein D, Musonda R, Allen S, Kumwenda N, Taha T, Gray G, McIntyre J, Karim SA, Sheppard HW, Gray CM; HIVNET 028 Study Team..

J Virol. 2004 Apr;78(7):3233-43.


Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.

Ramduth D, Day CL, Thobakgale CF, Mkhwanazi NP, de Pierres C, Reddy S, van der Stok M, Mncube Z, Nair K, Moodley ES, Kaufmann DE, Streeck H, Coovadia HM, Kiepiela P, Goulder PJ, Walker BD.

PLoS One. 2009;4(4):e5013. doi: 10.1371/journal.pone.0005013.


Relative dominance of Env-gp41-specific cytotoxic T lymphocytes responses in HIV-1 advanced infection.

Zhuang Y, Sun Y, Zhai S, Huang D, Zhao S, Wang S, Kang W, Li X, Walker BD, Altfeld M, Yu XG.

Curr HIV Res. 2008 May;6(3):239-45.


Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses.

Draenert R, Altfeld M, Brander C, Basgoz N, Corcoran C, Wurcel AG, Stone DR, Kalams SA, Trocha A, Addo MM, Goulder PJ, Walker BD.

J Immunol Methods. 2003 Apr 1;275(1-2):19-29.


Cytolytic T lymphocytes (CTLs) from HIV-1 subtype C-infected Indian patients recognize CTL epitopes from a conserved immunodominant region of HIV-1 Gag and Nef.

Thakar MR, Bhonge LS, Lakhashe SK, Shankarkumar U, Sane SS, Kulkarni SS, Mahajan BA, Paranjape RS.

J Infect Dis. 2005 Sep 1;192(5):749-59.


Human immunodeficiency virus-specific gamma interferon enzyme-linked immunospot assay responses targeting specific regions of the proteome during primary subtype C infection are poor predictors of the course of viremia and set point.

Gray CM, Mlotshwa M, Riou C, Mathebula T, de Assis Rosa D, Mashishi T, Seoighe C, Ngandu N, van Loggerenberg F, Morris L, Mlisana K, Williamson C, Karim SA; CAPRISA 002 Acute Infection Study Team..

J Virol. 2009 Jan;83(1):470-8. doi: 10.1128/JVI.01678-08.


De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection.

Allen TM, Yu XG, Kalife ET, Reyor LL, Lichterfeld M, John M, Cheng M, Allgaier RL, Mui S, Frahm N, Alter G, Brown NV, Johnston MN, Rosenberg ES, Mallal SA, Brander C, Walker BD, Altfeld M.

J Virol. 2005 Oct;79(20):12952-60.


HIV-1 Subtype C gag-specific T-cell responses in relation to human leukocyte antigens in a diverse population of HIV-infected Ethiopians.

Tsegaye A, Ran L, Wolday D, Petros B, Dorigo W, Piriou E, Messele T, Sanders E, Tilahun T, Eshetu D, Schuitemaker H, Coutinho RA, Miedema F, Borghans J, van Baarle D.

J Acquir Immune Defic Syndr. 2007 Aug 1;45(4):389-400.


A systematic comparison of methods to measure HIV-1 specific CD8 T cells.

Sun Y, Iglesias E, Samri A, Kamkamidze G, Decoville T, Carcelain G, Autran B.

J Immunol Methods. 2003 Jan 15;272(1-2):23-34.


Limited magnitude and breadth in the HLA-A2-restricted CD8 T-Cell response to Nef in children with vertically acquired HIV-1 infection.

Chandwani R, Jordan KA, Shacklett BL, Papasavvas E, Montaner LJ, Rosenberg MG, Nixon DF, Sandberg JK.

Scand J Immunol. 2004 Jan;59(1):109-14.


Correlation between gag-specific CD8 T-cell responses, viral load, and CD4 count in HIV-1 infection is dependent on disease status.

Jiao Y, Xie J, Li T, Han Y, Qiu Z, Zuo L, Wang A.

J Acquir Immune Defic Syndr. 2006 Jul;42(3):263-8.

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