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Items: 1 to 20 of 93

1.

A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex.

Reiser JB, Grégoire C, Darnault C, Mosser T, Guimezanes A, Schmitt-Verhulst AM, Fontecilla-Camps JC, Mazza G, Malissen B, Housset D.

Immunity. 2002 Mar;16(3):345-54.

2.

CDR3 loop flexibility contributes to the degeneracy of TCR recognition.

Reiser JB, Darnault C, Grégoire C, Mosser T, Mazza G, Kearney A, van der Merwe PA, Fontecilla-Camps JC, Housset D, Malissen B.

Nat Immunol. 2003 Mar;4(3):241-7. Epub 2003 Feb 3.

PMID:
12563259
3.

Point mutations in the beta chain CDR3 can alter the T cell receptor recognition pattern on an MHC class I/peptide complex over a broad interface area.

Goyarts EC, Vegh Z, Kalergis AM, Hörig H, Papadopoulos NJ, Young AC, Thomson CT, Chang HC, Joyce S, Nathenson SG.

Mol Immunol. 1998 Jul;35(10):593-607.

PMID:
9823758
4.

The crystal structure of a T cell receptor in complex with peptide and MHC class II.

Reinherz EL, Tan K, Tang L, Kern P, Liu J, Xiong Y, Hussey RE, Smolyar A, Hare B, Zhang R, Joachimiak A, Chang HC, Wagner G, Wang J.

Science. 1999 Dec 3;286(5446):1913-21.

5.

Structure and binding kinetics of three different human CD1d-alpha-galactosylceramide-specific T cell receptors.

Gadola SD, Koch M, Marles-Wright J, Lissin NM, Shepherd D, Matulis G, Harlos K, Villiger PM, Stuart DI, Jakobsen BK, Cerundolo V, Jones EY.

J Exp Med. 2006 Mar 20;203(3):699-710. Epub 2006 Mar 6.

6.

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.

Eckle SB, Birkinshaw RW, Kostenko L, Corbett AJ, McWilliam HE, Reantragoon R, Chen Z, Gherardin NA, Beddoe T, Liu L, Patel O, Meehan B, Fairlie DP, Villadangos JA, Godfrey DI, Kjer-Nielsen L, McCluskey J, Rossjohn J.

J Exp Med. 2014 Jul 28;211(8):1585-600. doi: 10.1084/jem.20140484. Epub 2014 Jul 21.

7.

Topology of T cell receptor-peptide/class I MHC interaction defined by charge reversal complementation and functional analysis.

Chang HC, Smolyar A, Spoerl R, Witte T, Yao Y, Goyarts EC, Nathenson SG, Reinherz EL.

J Mol Biol. 1997 Aug 15;271(2):278-93.

PMID:
9268659
8.

TCR scanning of peptide/MHC through complementary matching of receptor and ligand molecular flexibility.

Hawse WF, De S, Greenwood AI, Nicholson LK, Zajicek J, Kovrigin EL, Kranz DM, Garcia KC, Baker BM.

J Immunol. 2014 Mar 15;192(6):2885-91. doi: 10.4049/jimmunol.1302953. Epub 2014 Feb 12.

9.

A new twist in TCR diversity revealed by a forbidden alphabeta TCR.

McBeth C, Seamons A, Pizarro JC, Fleishman SJ, Baker D, Kortemme T, Goverman JM, Strong RK.

J Mol Biol. 2008 Feb 1;375(5):1306-19. Epub 2007 Nov 17.

10.

On defining the rules for interactions between the T cell receptor and its ligand: a critical role for a specific amino acid residue of the T cell receptor beta chain.

Wang F, Ono T, Kalergis AM, Zhang W, DiLorenzo TP, Lim K, Nathenson SG.

Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5217-22.

11.

Structure-function studies of T-cell receptor-superantigen interactions.

Li H, Llera A, Mariuzza RA.

Immunol Rev. 1998 Jun;163:177-86. Review.

PMID:
9700510
12.

The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain.

Housset D, Mazza G, Grégoire C, Piras C, Malissen B, Fontecilla-Camps JC.

EMBO J. 1997 Jul 16;16(14):4205-16.

13.

Structural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by Vα CDR3.

Deng L, Langley RJ, Wang Q, Topalian SL, Mariuzza RA.

Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14960-5. doi: 10.1073/pnas.1207186109. Epub 2012 Aug 28.

14.

Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen.

Garcia KC, Degano M, Pease LR, Huang M, Peterson PA, Teyton L, Wilson IA.

Science. 1998 Feb 20;279(5354):1166-72.

15.

Effect of CDR3 sequences and distal V gene residues in regulating TCR-MHC contacts and ligand specificity.

Stadinski BD, Trenh P, Duke B, Huseby PG, Li G, Stern LJ, Huseby ES.

J Immunol. 2014 Jun 15;192(12):6071-82. doi: 10.4049/jimmunol.1303209. Epub 2014 May 9.

16.

The specificity of TCR/pMHC interaction.

Rudolph MG, Wilson IA.

Curr Opin Immunol. 2002 Feb;14(1):52-65. Review.

PMID:
11790533
17.

A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned.

Gras S, Burrows SR, Turner SJ, Sewell AK, McCluskey J, Rossjohn J.

Immunol Rev. 2012 Nov;250(1):61-81. doi: 10.1111/j.1600-065X.2012.01159.x. Review.

PMID:
23046123
18.

TcR recognition of the MHC-peptide dimer: structural properties of a ternary complex.

Vasmatzis G, Cornette J, Sezerman U, DeLisi C.

J Mol Biol. 1996 Aug 9;261(1):72-89.

PMID:
8760503
19.

Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor.

Rudolph MG, Huang M, Teyton L, Wilson IA.

J Mol Biol. 2001 Nov 16;314(1):1-8.

PMID:
11724527
20.

Shortening of complementarity determining region 3 of the T cell receptor α chain during thymocyte development.

Matsutani T, Ogata M, Fujii Y, Kitaura K, Nishimoto N, Suzuki R, Itoh T.

Mol Immunol. 2011 Jan;48(4):623-9. doi: 10.1016/j.molimm.2010.11.003. Epub 2010 Dec 3.

PMID:
21126768

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