Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 79

1.

5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition.

Auberson YP, Allgeier H, Bischoff S, Lingenhoehl K, Moretti R, Schmutz M.

Bioorg Med Chem Lett. 2002 Apr 8;12(7):1099-102.

PMID:
11909726
2.
3.

Structure-activity relationships of alkyl- and alkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones: potent and systemically active antagonists for the glycine site of the NMDA receptor.

Cai SX, Kher SM, Zhou ZL, Ilyin V, Espitia SA, Tran M, Hawkinson JE, Woodward RM, Weber E, Keana JF.

J Med Chem. 1997 Feb 28;40(5):730-8.

PMID:
9057859
4.

A new pyrrolyl-quinoxalinedione series of non-NMDA glutamate receptor antagonists: pharmacological characterization and comparison with NBQX and valproate in the kindling model of epilepsy.

Löscher W, Lehmann H, Behl B, Seemann D, Teschendorf HJ, Hofmann HP, Lubisch W, Höger T, Lemaire HG, Gross G.

Eur J Neurosci. 1999 Jan;11(1):250-62.

PMID:
9987029
5.

Synthesis and structure-activity relationships of substituted 1,4-dihydroquinoxaline-2,3-diones: antagonists of N-methyl-D-aspartate (NMDA) receptor glycine sites and non-NMDA glutamate receptors.

Keana JF, Kher SM, Cai SX, Dinsmore CM, Glenn AG, Guastella J, Huang JC, Ilyin V, Lü Y, Mouser PL, et al.

J Med Chem. 1995 Oct 27;38(22):4367-79.

PMID:
7473565
8.

Synthesis of N-substituted 4-(4-hydroxyphenyl)piperidines, 4-(4-hydroxybenzyl)piperidines, and (+/-)-3-(4-hydroxyphenyl)pyrrolidines: selective antagonists at the 1A/2B NMDA receptor subtype.

Guzikowski AP, Tamiz AP, Acosta-Burruel M, Hong-Bae S, Cai SX, Hawkinson JE, Keana JF, Kesten SR, Shipp CT, Tran M, Whittemore ER, Woodward RM, Wright JL, Zhou ZL.

J Med Chem. 2000 Mar 9;43(5):984-94.

PMID:
10715162
9.

5-Aminomethylquinoxaline-2,3-diones, Part III: Arylamide derivatives as highly potent and selective glycine-site NMDA receptor antagonists.

Acklin P, Allgeier H, Auberson YP, Bischoff S, Ofner S, Sauer D, Schmutz M.

Bioorg Med Chem Lett. 1998 Mar 3;8(5):493-8.

PMID:
9871605
10.

Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors.

Hess SD, Daggett LP, Crona J, Deal C, Lu CC, Urrutia A, Chavez-Noriega L, Ellis SB, Johnson EC, Veliçelebi G.

J Pharmacol Exp Ther. 1996 Aug;278(2):808-16.

PMID:
8768735
11.

5-(N-oxyaza)-7-substituted-1,4-dihydroquinoxaline-2,3-diones: novel, systemically active and broad spectrum antagonists for NMDA/glycine, AMPA, and kainate receptors.

Cai SX, Huang JC, Espitia SA, Tran M, Ilyin VI, Hawkinson JE, Woodward RM, Weber E, Keana JF.

J Med Chem. 1997 Oct 24;40(22):3679-86.

PMID:
9357535
12.
14.

Pharmacology of ACEA-1416: a potent systemically active NMDA receptor glycine site antagonist.

Ilyin VI, Whittemore ER, Tran M, Shen KZ, Cai SX, Kher SM, Keana JF, Weber E, Woodward RM.

Eur J Pharmacol. 1996 Aug 29;310(2-3):107-14.

PMID:
8884205
15.
17.

Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists.

Zhou ZL, Kher SM, Cai SX, Whittemore ER, Espitia SA, Hawkinson JE, Tran M, Woodward RM, Weber E, Keana JF.

Bioorg Med Chem. 2003 Apr 17;11(8):1769-80.

PMID:
12659763
18.

Synthesis, radiolabelling and biological characterization of (D)-7-iodo-N-(1-phosphonoethyl)-5-aminomethylquinoxaline-2,3-dione, a glycine-binding site antagonist of NMDA receptors.

Ametamey SM, Kokic M, Carrey-Rémy N, Bläuenstein P, Willmann M, Bischoff S, Schmutz M, Schubiger PA, Auberson YP.

Bioorg Med Chem Lett. 2000 Jan 3;10(1):75-8.

PMID:
10636248
19.
20.

Supplemental Content

Support Center